-
1
-
-
33744987414
-
Generation of C5a in the absence of C3: A new complement activation pathway
-
DOI 10.1038/nm1419, PII N1419
-
Huber-Lang, M., J. V. Sarma, F. S. Zetoune, D. Rittirsch, T. A. Neff, S. R. McGuire, J. D. Lambris, R. L. Warner, M. A. Flierl, L. M. Hoesel, et al. 2006. Generation of C5a in the absence of C3: a new complement activation pathway. Nat. Med. 12: 682-687. (Pubitemid 43865238)
-
(2006)
Nature Medicine
, vol.12
, Issue.6
, pp. 682-687
-
-
Huber-Lang, M.1
Sarma, J.V.2
Zetoune, F.S.3
Rittirsch, D.4
Neff, T.A.5
McGuire, S.R.6
Lambris, J.D.7
Warner, R.L.8
Flierl, M.A.9
Hoesel, L.M.10
Gebhard, F.11
Younger, J.G.12
Drouin, S.M.13
Wetsel, R.A.14
Ward, P.A.15
-
2
-
-
33646367451
-
Complement decay accelerating factor (DAF)/CD55 in cancer
-
DOI 10.1007/s00262-006-0136-8
-
Spendlove, I., J. M. Ramage, R. Bradley, C. Harris, and L. G. Durrant. 2006. Complement decay accelerating factor (DAF)/CD55 in cancer. Cancer Immunol. Immunother. 55: 987-995. (Pubitemid 43673590)
-
(2006)
Cancer Immunology, Immunotherapy
, vol.55
, Issue.8
, pp. 987-995
-
-
Spendlove, I.1
Ramage, J.M.2
Bradley, R.3
Harris, C.4
Durrant, L.G.5
-
3
-
-
58149357133
-
The role of membrane complement regulatory proteins in cancer immunotherapy
-
Yan, J., D. J. Allendorf, B. Li, R. Yan, R. Hansen, and R. Donev. 2008. The role of membrane complement regulatory proteins in cancer immunotherapy. Adv. Exp. Med. Biol. 632: 159-174.
-
(2008)
Adv. Exp. Med. Biol.
, vol.632
, pp. 159-174
-
-
Yan, J.1
Allendorf, D.J.2
Li, B.3
Yan, R.4
Hansen, R.5
Donev, R.6
-
4
-
-
17644388462
-
Role of C5a in inflammatory responses
-
Guo, R. F., and P. A. Ward. 2005. Role of C5a in inflammatory responses. Annu. Rev. Immunol. 23: 821-852.
-
(2005)
Annu. Rev. Immunol.
, vol.23
, pp. 821-852
-
-
Guo, R.F.1
Ward, P.A.2
-
5
-
-
79952835560
-
New insights of an old defense system: Structure, function, and clinical relevance of the complement system
-
Ehrnthaller, C., A. Ignatius, F. Gebhard, and M. Huber-Lang. 2011. New insights of an old defense system: structure, function, and clinical relevance of the complement system. Mol. Med. 17: 317-329.
-
(2011)
Mol. Med.
, vol.17
, pp. 317-329
-
-
Ehrnthaller, C.1
Ignatius, A.2
Gebhard, F.3
Huber-Lang, M.4
-
6
-
-
67349174213
-
Combined yeast-derived beta-glucan with anti-tumor monoclonal antibody for cancer immunotherapy
-
Liu, J., L. Gunn, R. Hansen, and J. Yan. 2009. Combined yeast-derived beta-glucan with anti-tumor monoclonal antibody for cancer immunotherapy. Exp. Mol. Pathol. 86: 208-214.
-
(2009)
Exp. Mol. Pathol.
, vol.86
, pp. 208-214
-
-
Liu, J.1
Gunn, L.2
Hansen, R.3
Yan, J.4
-
7
-
-
18944394199
-
4-amplified neutrophil chemotaxis is essential in tumor immunotherapy facilitated by anti-tumor monoclonal antibody and β-glucan
-
Allendorf, D. J., J. Yan, G. D. Ross, R. D. Hansen, J. T. Baran, K. Subbarao, L. Wang, and B. Haribabu. 2005. C5a-mediated leukotriene B4-amplified neutrophil chemotaxis is essential in tumor immunotherapy facilitated by anti-tumor monoclonal antibody and beta-glucan. J. Immunol. 174: 7050-7056. (Pubitemid 40705670)
-
(2005)
Journal of Immunology
, vol.174
, Issue.11
, pp. 7050-7056
-
-
Allendorf, D.J.1
Yan, J.2
Ross, G.D.3
Hansen, R.D.4
Baran, J.T.5
Subbarao, K.6
Wang, L.7
Haribabu, B.8
-
8
-
-
34547619005
-
Combined yeast β-glucan and antitumor monoclonal antibody therapy requires C5a-mediated neutrophil chemotaxis via regulation of decay-accelerating factor CD55
-
DOI 10.1158/0008-5472.CAN-07-1465
-
Li, B., D. J. Allendorf, R. Hansen, J. Marroquin, D. E. Cramer, C. L. Harris, and J. Yan. 2007. Combined yeast β-glucan and antitumor monoclonal antibody therapy requires C5a-mediated neutrophil chemotaxis via regulation of decay-accelerating factor CD55. Cancer Res. 67: 7421-7430. (Pubitemid 47206572)
-
(2007)
Cancer Research
, vol.67
, Issue.15
, pp. 7421-7430
-
-
Li, B.1
Allendorf, D.J.2
Hansen, R.3
Marroquin, J.4
Cramer, D.E.5
Harris, C.L.6
Yan, J.7
-
9
-
-
77955493452
-
Decreased survival of human breast cancer cells expressing HER2/neu on in vitro incubation with an anti-HER2/neu antibody fused to C5a or C5a desArg
-
Fuenmayor, J., K. Perez-Vazquez, D. Perez-Witzke, M. L. Penichet, and R. F. Montano. 2010. Decreased survival of human breast cancer cells expressing HER2/neu on in vitro incubation with an anti-HER2/neu antibody fused to C5a or C5a desArg. Mol. Cancer Ther. 9: 2175-2185.
-
(2010)
Mol. Cancer Ther.
, vol.9
, pp. 2175-2185
-
-
Fuenmayor, J.1
Perez-Vazquez, K.2
Perez-Witzke, D.3
Penichet, M.L.4
Montano, R.F.5
-
10
-
-
23944525048
-
Expression of complement protein C5a in a murine mammary cancer model: Tumor regression by interference with the cell cycle
-
Kim, D. Y., C. B. Martin, S. N. Lee, and B. K. Martin. 2005. Expression of complement protein C5a in a murine mammary cancer model: tumor regression by interference with the cell cycle. Cancer Immunol. Immunother. 54: 1026-1037.
-
(2005)
Cancer Immunol. Immunother.
, vol.54
, pp. 1026-1037
-
-
Kim, D.Y.1
Martin, C.B.2
Lee, S.N.3
Martin, B.K.4
-
11
-
-
54549109936
-
Modulation of the antitumor immune response by complement
-
Markiewski, M. M., R. A. DeAngelis, F. Benencia, S. K. Ricklin-Lichtsteiner, A. Koutoulaki, C. Gerard, G. Coukos, and J. D. Lambris. 2008. Modulation of the antitumor immune response by complement. Nat. Immunol. 9: 1225-1235.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 1225-1235
-
-
Markiewski, M.M.1
DeAngelis, R.A.2
Benencia, F.3
Ricklin-Lichtsteiner, S.K.4
Koutoulaki, A.5
Gerard, C.6
Coukos, G.7
Lambris, J.D.8
-
13
-
-
66549124166
-
Is complement good or bad for cancer patients? A new perspective on an old dilemma
-
Markiewski, M. M., and J. D. Lambris. 2009. Is complement good or bad for cancer patients? A new perspective on an old dilemma. Trends Immunol. 30: 286-292.
-
(2009)
Trends Immunol.
, vol.30
, pp. 286-292
-
-
Markiewski, M.M.1
Lambris, J.D.2
-
15
-
-
33746190826
-
Yeast β-glucan amplifies phagocyte killing of iC3b-opsonized tumor cells via complement receptor 3-Syk-phosphatidylinositol 3-Kinase pathway
-
Li, B., D. J. Allendorf, R. Hansen, J. Marroquin, C. Ding, D. E. Cramer, and J. Yan. 2006. Yeast beta-glucan amplifies phagocyte killing of iC3b-opsonized tumor cells via complement receptor 3-Syk-phosphatidylinositol 3-kinase pathway. J. Immunol. 177: 1661-1669. (Pubitemid 44092502)
-
(2006)
Journal of Immunology
, vol.177
, Issue.3
, pp. 1661-1669
-
-
Li, B.1
Allendorf, D.J.2
Hansen, R.3
Marroquin, J.4
Ding, C.5
Cramer, D.E.6
Yan, J.7
-
16
-
-
33646727378
-
Transferable anticancer innate immunity in spontaneous regression/complete resistance mice
-
Hicks, A. M., G. Riedlinger, M. C. Willingham, M. A. Alexander-Miller, C. Von Kap-Herr, M. J. Pettenati, A. M. Sanders, H. M. Weir, W. Du, J. Kim, et al. 2006. Transferable anticancer innate immunity in spontaneous regression/complete resistance mice. Proc. Natl. Acad. Sci. USA 103: 7753-7758.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 7753-7758
-
-
Hicks, A.M.1
Riedlinger, G.2
Willingham, M.C.3
Alexander-Miller, M.A.4
Von Kap-Herr, C.5
Pettenati, M.J.6
Sanders, A.M.7
Weir, H.M.8
Du, W.9
Kim, J.10
-
17
-
-
53549124398
-
NKG2D ligands in tumor immunity
-
Nausch, N., and A. Cerwenka. 2008. NKG2D ligands in tumor immunity. Oncogene 27: 5944-5958.
-
(2008)
Oncogene
, vol.27
, pp. 5944-5958
-
-
Nausch, N.1
Cerwenka, A.2
-
19
-
-
79960411324
-
CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis
-
Qian, B. Z., J. Li, H. Zhang, T. Kitamura, J. Zhang, L. R. Campion, E. A. Kaiser, L. A. Snyder, and J. W. Pollard. 2011. CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis. Nature 475: 222-225.
-
(2011)
Nature
, vol.475
, pp. 222-225
-
-
Qian, B.Z.1
Li, J.2
Zhang, H.3
Kitamura, T.4
Zhang, J.5
Campion, L.R.6
Kaiser, E.A.7
Snyder, L.A.8
Pollard, J.W.9
-
20
-
-
77953497686
-
Complement drives Th17 cell differentiation and triggers autoimmune arthritis
-
Hashimoto, M., K. Hirota, H. Yoshitomi, S. Maeda, S. Teradaira, S. Akizuki, P. Prieto-Martin, T. Nomura, N. Sakaguchi, J. Köhl, et al. 2010. Complement drives Th17 cell differentiation and triggers autoimmune arthritis. J. Exp. Med. 207: 1135-1143.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 1135-1143
-
-
Hashimoto, M.1
Hirota, K.2
Yoshitomi, H.3
Maeda, S.4
Teradaira, S.5
Akizuki, S.6
Prieto-Martin, P.7
Nomura, T.8
Sakaguchi, N.9
Köhl, J.10
-
21
-
-
70349260730
-
Complement promotes the development of inflammatory T-helper 17 cells through synergistic interaction with Toll-like receptor signaling and interleukin-6 production
-
Fang, C., X. Zhang, T. Miwa, and W. C. Song. 2009. Complement promotes the development of inflammatory T-helper 17 cells through synergistic interaction with Toll-like receptor signaling and interleukin-6 production. Blood 114: 1005-1015.
-
(2009)
Blood
, vol.114
, pp. 1005-1015
-
-
Fang, C.1
Zhang, X.2
Miwa, T.3
Song, W.C.4
-
22
-
-
82755190055
-
C5a regulates NKT and NK cell functions in sepsis
-
Fusakio, M. E., J. P. Mohammed, Y. Laumonnier, K. Hoebe, J. Köhl, and J. Mattner. 2011. C5a regulates NKT and NK cell functions in sepsis. J. Immunol. 187: 5805-5812.
-
(2011)
J. Immunol.
, vol.187
, pp. 5805-5812
-
-
Fusakio, M.E.1
Mohammed, J.P.2
Laumonnier, Y.3
Hoebe, K.4
Köhl, J.5
Mattner, J.6
-
23
-
-
58149334990
-
Can NK cells be a therapeutic target in human cancer?
-
Chan, C. J., D. M. Andrews, and M. J. Smyth. 2008. Can NK cells be a therapeutic target in human cancer? Eur. J. Immunol. 38: 2964-2968.
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 2964-2968
-
-
Chan, C.J.1
Andrews, D.M.2
Smyth, M.J.3
-
24
-
-
0036831613
-
New aspects of natural-killer-cell surveillance and therapy of cancer
-
DOI 10.1038/nrc928
-
Smyth, M. J., Y. Hayakawa, K. Takeda, and H. Yagita. 2002. New aspects of natural-killer-cell surveillance and therapy of cancer. Nat. Rev. Cancer 2: 850-861. (Pubitemid 37328903)
-
(2002)
Nature Reviews Cancer
, vol.2
, Issue.11
, pp. 850-861
-
-
Smyth, M.J.1
Hayakawa, Y.2
Takeda, K.3
Yagita, H.4
-
25
-
-
77950950894
-
Macrophage diversity enhances tumor progression and metastasis
-
Qian, B. Z., and J. W. Pollard. 2010. Macrophage diversity enhances tumor progression and metastasis. Cell 141: 39-51.
-
(2010)
Cell
, vol.141
, pp. 39-51
-
-
Qian, B.Z.1
Pollard, J.W.2
-
26
-
-
77952937103
-
The M1 form of tumor-associated macrophages in non-small cell lung cancer is positively associated with survival time
-
Ma, J., L. Liu, G. Che, N. Yu, F. Dai, and Z. You. 2010. The M1 form of tumor-associated macrophages in non-small cell lung cancer is positively associated with survival time. BMC Cancer 10: 112.
-
(2010)
BMC Cancer
, vol.10
, pp. 112
-
-
Ma, J.1
Liu, L.2
Che, G.3
Yu, N.4
Dai, F.5
You, Z.6
-
27
-
-
77956212940
-
Tumor-conditioned macrophages secrete migration-stimulating factor: A new marker for M2-polarization, influencing tumor cell motility
-
Solinas, G., S. Schiarea, M. Liguori, M. Fabbri, S. Pesce, L. Zammataro, F. Pasqualini, M. Nebuloni, C. Chiabrando, A. Mantovani, and P. Allavena. 2010. Tumor-conditioned macrophages secrete migration-stimulating factor: a new marker for M2-polarization, influencing tumor cell motility. J. Immunol. 185: 642-652.
-
(2010)
J. Immunol.
, vol.185
, pp. 642-652
-
-
Solinas, G.1
Schiarea, S.2
Liguori, M.3
Fabbri, M.4
Pesce, S.5
Zammataro, L.6
Pasqualini, F.7
Nebuloni, M.8
Chiabrando, C.9
Mantovani, A.10
Allavena, P.11
-
28
-
-
61349100687
-
Myeloid-derived suppressor cells as regulators of the immune system
-
Gabrilovich, D. I., and S. Nagaraj. 2009. Myeloid-derived suppressor cells as regulators of the immune system. Nat. Rev. Immunol. 9: 162-174.
-
(2009)
Nat. Rev. Immunol.
, vol.9
, pp. 162-174
-
-
Gabrilovich, D.I.1
Nagaraj, S.2
-
29
-
-
78149330949
-
HIF-1a regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment
-
Corzo, C. A., T. Condamine, L. Lu, M. J. Cotter, J. I. Youn, P. Cheng, H. I. Cho, E. Celis, D. G. Quiceno, T. Padhya, et al. 2010. HIF-1a regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment. J. Exp. Med. 207: 2439-2453.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 2439-2453
-
-
Corzo, C.A.1
Condamine, T.2
Lu, L.3
Cotter, M.J.4
Youn, J.I.5
Cheng, P.6
Cho, H.I.7
Celis, E.8
Quiceno, D.G.9
Padhya, T.10
-
30
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan, D., and R. A. Weinberg. 2000. The hallmarks of cancer. Cell 100: 57-70. (Pubitemid 30046295)
-
(2000)
Cell
, vol.100
, Issue.1
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
31
-
-
79959333446
-
Canonical hedgehog signaling augments tumor angiogenesis by induction of VEGF-A in stromal perivascular cells
-
Chen, W., T. Tang, J. Eastham-Anderson, D. Dunlap, B. Alicke, M. Nannini, S. Gould, R. Yauch, Z. Modrusan, K. J. DuPree, et al. 2011. Canonical hedgehog signaling augments tumor angiogenesis by induction of VEGF-A in stromal perivascular cells. Proc. Natl. Acad. Sci. USA 108: 9589-9594.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 9589-9594
-
-
Chen, W.1
Tang, T.2
Eastham-Anderson, J.3
Dunlap, D.4
Alicke, B.5
Nannini, M.6
Gould, S.7
Yauch, R.8
Modrusan, Z.9
DuPree, K.J.10
-
32
-
-
79960130552
-
Effects of inflammatory factors on mesenchymal stem cells and their role in the promotion of tumor angiogenesis in colon cancer
-
Liu, Y., Z. P. Han, S. S. Zhang, Y. Y. Jing, X. X. Bu, C. Y. Wang, K. Sun, G. C. Jiang, X. Zhao, R. Li, et al. 2011. Effects of inflammatory factors on mesenchymal stem cells and their role in the promotion of tumor angiogenesis in colon cancer. J. Biol. Chem. 286: 25007-25015.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 25007-25015
-
-
Liu, Y.1
Han, Z.P.2
Zhang, S.S.3
Jing, Y.Y.4
Bu, X.X.5
Wang, C.Y.6
Sun, K.7
Jiang, G.C.8
Zhao, X.9
Li, R.10
-
33
-
-
78649482676
-
Complement-mediated inhibition of neovascularization reveals a point of convergence between innate immunity and angiogenesis
-
Langer, H. F., K. J. Chung, V. V. Orlova, E. Y. Choi, S. Kaul, M. J. Kruhlak, M. Alatsatianos, R. A. Deangelis, P. A. Roche, P. Magotti, et al. 2010. Complement-mediated inhibition of neovascularization reveals a point of convergence between innate immunity and angiogenesis. Blood 116: 4395-4403.
-
(2010)
Blood
, vol.116
, pp. 4395-4403
-
-
Langer, H.F.1
Chung, K.J.2
Orlova, V.V.3
Choi, E.Y.4
Kaul, S.5
Kruhlak, M.J.6
Alatsatianos, M.7
Deangelis, R.A.8
Roche, P.A.9
Magotti, P.10
-
34
-
-
70249140303
-
Myeloid-derived suppressor cells down-regulate L-selectin expression on CD4+ and CD8+ T cells
-
Hanson, E. M., V. K. Clements, P. Sinha, D. Ilkovitch, and S. Ostrand-Rosenberg. 2009. Myeloid-derived suppressor cells down-regulate L-selectin expression on CD4+ and CD8+ T cells. J. Immunol. 183: 937-944.
-
(2009)
J. Immunol.
, vol.183
, pp. 937-944
-
-
Hanson, E.M.1
Clements, V.K.2
Sinha, P.3
Ilkovitch, D.4
Ostrand-Rosenberg, S.5
-
35
-
-
77955549860
-
Myeloid-derived suppressor cells: More mechanisms for inhibiting antitumor immunity
-
Ostrand-Rosenberg, S. 2010. Myeloid-derived suppressor cells: more mechanisms for inhibiting antitumor immunity. Cancer Immunol. Immunother. 59: 1593-1600.
-
(2010)
Cancer Immunol. Immunother.
, vol.59
, pp. 1593-1600
-
-
Ostrand-Rosenberg, S.1
-
36
-
-
5444259851
-
The complement system in regulation of adaptive immunity
-
DOI 10.1038/ni1113
-
Carroll, M. C. 2004. The complement system in regulation of adaptive immunity. Nat. Immunol. 5: 981-986. (Pubitemid 41057714)
-
(2004)
Nature Immunology
, vol.5
, Issue.10
, pp. 981-986
-
-
Carroll, M.C.1
-
37
-
-
33644845646
-
Dendritic cell synthesis of C3 is required for full T cell activation and development of a Th1 phenotype
-
Peng, Q., K. Li, H. Patel, S. H. Sacks, and W. Zhou. 2006. Dendritic cell synthesis of C3 is required for full T cell activation and development of a Th1 phenotype. J. Immunol. 176: 3330-3341. (Pubitemid 43363979)
-
(2006)
Journal of Immunology
, vol.176
, Issue.6
, pp. 3330-3341
-
-
Peng, Q.1
Li, K.2
Patel, H.3
Sacks, S.H.4
Zhou, W.5
-
38
-
-
40249116606
-
Locally produced complement fragments C5a and C3a provide both costimulatory and survival signals to naive CD4+ T cells
-
Strainic, M. G., J. Liu, D. Huang, F. An, P. N. Lalli, N. Muqim, V. S. Shapiro, G. R. Dubyak, P. S. Heeger, and M. E. Medof. 2008. Locally produced complement fragments C5a and C3a provide both costimulatory and survival signals to naive CD4+ T cells. Immunity 28: 425-435.
-
(2008)
Immunity
, vol.28
, pp. 425-435
-
-
Strainic, M.G.1
Liu, J.2
Huang, D.3
An, F.4
Lalli, P.N.5
Muqim, N.6
Shapiro, V.S.7
Dubyak, G.R.8
Heeger, P.S.9
Medof, M.E.10
-
39
-
-
52649176344
-
Locally produced C5a binds to T cell-expressed C5aR to enhance effector T-cell expansion by limiting antigen-induced apoptosis
-
Lalli, P. N., M. G. Strainic, M. Yang, F. Lin, M. E. Medof, and P. S. Heeger. 2008. Locally produced C5a binds to T cell-expressed C5aR to enhance effector T-cell expansion by limiting antigen-induced apoptosis. Blood 112: 1759-1766.
-
(2008)
Blood
, vol.112
, pp. 1759-1766
-
-
Lalli, P.N.1
Strainic, M.G.2
Yang, M.3
Lin, F.4
Medof, M.E.5
Heeger, P.S.6
-
40
-
-
77749285675
-
C5a receptor-deficient dendritic cells promote induction of Treg and Th17 cells
-
Weaver, D. J., Jr., E. S. Reis, M. K. Pandey, G. Köhl, N. Harris, C. Gerard, and J. Köhl. 2010. C5a receptor-deficient dendritic cells promote induction of Treg and Th17 cells. Eur. J. Immunol. 40: 710-721.
-
(2010)
Eur. J. Immunol.
, vol.40
, pp. 710-721
-
-
Weaver Jr., D.J.1
Reis, E.S.2
Pandey, M.K.3
Köhl, G.4
Harris, N.5
Gerard, C.6
Köhl, J.7
-
41
-
-
49749103028
-
+ T cell immunity to lymphocytic choriomeningitis virus infection in decay-accelerating factor-deficient mice
-
+ T cell immunity to lymphocytic choriomeningitis virus infection in decay-accelerating factor-deficient mice. J. Immunol. 179: 3178-3186.
-
(2007)
J. Immunol.
, vol.179
, pp. 3178-3186
-
-
Fang, C.1
Miwa, T.2
Shen, H.3
Song, W.C.4
-
43
-
-
1142310879
-
The dark side of C5a in sepsis
-
Ward, P. A. 2004. The dark side of C5a in sepsis. Nat. Rev. Immunol. 4: 133-142. (Pubitemid 38209207)
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(2004)
Nature Reviews Immunology
, vol.4
, Issue.2
, pp. 133-142
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Ward, P.A.1
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