Host Defense and Tolerance: Unique Challenges in the Placenta

PLoS Pathogens

Volumn 8, Issue 8, 2012, Pages

  Zeldovich, Varvara B ^a,b   Bakardjiev, Anna I ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD PLACENTA BARRIER; BLOODBORNE BACTERIUM; CELL FUNCTION; HOST RESISTANCE; HUMAN; IMMUNE DEFICIENCY; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; INFECTION PREVENTION; INNATE IMMUNITY; NONHUMAN; PLACENTA; PLACENTA FUNCTION; PREGNANCY; PREGNANCY COMPLICATION; REVIEW; SYNCYTIUM; TROPHOBLAST;

ANIMALS; FEMALE; IMMUNE TOLERANCE; PLACENTA; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS;

EID: 84866146546     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002804     Document Type: Review

References (32)

1. Medawar PB, (1953) Some immunological and endocrinological problems raised by the evolution of viviparity in vertebrates. Symp Soc Exp Biol pp. 320-338.
2. Mor G, Cardenas I, Abrahams V, Guller S, (2011) Inflammation and pregnancy: the role of the immune system at the implantation site. Ann N Y Acad of Sci 1221: 80-87.
3. Romero R, Espinoza J, Goncalves LF, Kusanovic JP, Friel L, et al. (2007) The role of inflammation and infection in preterm birth. Semina Reprod Med 25: 21-39.
4. Matzinger P, (2002) The danger model: a renewed sense of self. Science 296: 301-305.
5. Fisher S, Genbacev O, Maidji E, Pereira L, (2000) Human cytomegalovirus infection of placental cytotrophoblasts in vitro and in utero: implications for transmission and pathogenesis. J Virol 74: 6808-6820.
6. Robbins JR, Skrzypczynska KM, Zeldovich VB, Kapidzic M, Bakardjiev AI, (2010) Placental syncytiotrophoblast constitutes a major barrier to vertical transmission of Listeria monocytogenes. PLoS Pathog 6: e1000732 doi:10.1371/journal.ppat.1000732.
7. Robbins JR, Zeldovich VB, Poukchanski A, Boothroyd JC, Bakardjiev AI, (2012) Tissue barriers of the human placenta to infection with Toxoplasma gondii. Infect Immun 80: 418-428.
8. Leiser R, Kaufmann P, (1994) Placental structure: in a comparative aspect. Exp Clin Endocrinol 102: 122-134.
9. Delorme-Axford E, Coyne CB, (2011) The actin cytoskeleton as a barrier to virus infection of polarized epithelial cells. Viruses 3: 2462-2477.
10. Lecuit M, Vandormael-Pournin S, Lefort J, Huerre M, Gounon P, et al. (2001) A transgenic model for listeriosis: role of internalin in crossing the intestinal barrier. Science 292: 1722-1725.
11. Pentecost M, Otto G, Theriot JA, Amieva MR, (2006) Listeria monocytogenes invades the epithelial junctions at sites of cell extrusion. PLoS Pathog 2: e3 doi:10.1371/journal.ppat.0020003.
12. Lecuit M, Nelson DM, Smith SD, Khun H, Huerre M, et al. (2004) Targeting and crossing of the human maternofetal barrier by Listeria monocytogenes: role of internalin interaction with trophoblast E-cadherin. Proc Natl Acad Sci U S A 101: 6152-6157.
13. Koi H, Zhang J, Makrigiannakis A, Getsios S, MacCalman CD, et al. (2002) Syncytiotrophoblast is a barrier to maternal-fetal transmission of herpes simplex virus. Biol Reprod 67: 1572-1579.
14. Ley K, Laudanna C, Cybulsky MI, Nourshargh S, (2007) Getting to the site of inflammation: the leukocyte adhesion cascade updated. Nat Rev Immunol 7: 678-689.
15. Nelson WJ, (2009) Remodeling epithelial cell organization: transitions between front-rear and apical-basal polarity. Cold Spring Harb Perspect Biol 1: a000513.
16. Stavru F, Bouillaud F, Sartori A, Ricquier D, Cossart P, (2011) Listeria monocytogenes transiently alters mitochondrial dynamics during infection. Proc Natl Acad Sci U S A 108: 3612-3617.
17. Wasilewski M, Semenzato M, Rafelski SM, Robbins J, Bakardjiev AI, et al. (2012) Optic atrophy 1-dependent mitochondrial remodeling controls steroidogenesis in trophoblasts. Curr Biol 22: 1228-1234.
18. Diaz-Lujan C, Triquell MF, Schijman A, Paglini P, Fretes RE, (2012) Differential susceptibility of isolated human trophoblasts to infection by Trypanosoma cruzi. Placenta 33: 264-270.
19. Tagliani E, Shi C, Nancy P, Tay CS, Pamer EG, et al. (2011) Coordinate regulation of tissue macrophage and dendritic cell population dynamics by CSF-1. J Exp Med 208: 1901-1916.
20. Robbins JR, Bakardjiev AI, (2012) Pathogens and the placental fortress. Curr Opin Microbiol 15: 36-43.
21. Redline RW, Lu CY, (1987) Role of local immunosuppression in murine fetoplacental listeriosis. J Clin Invest 79: 1234-1241.
22. Ferro EA, Silva DA, Bevilacqua E, Mineo JR, (2002) Effect of Toxoplasma gondii infection kinetics on trophoblast cell population in Calomys callosus, a model of congenital toxoplasmosis. Infect Immun 70: 7089-7094.
23. Zeldovich VB, Robbins JR, Kapidzic M, Lauer P, Bakardjiev AI, (2011) Invasive extravillous trophoblasts restrict intracellular growth and spread of Listeria monocytogenes. PLoS Pathog 7: e1002005 doi:10.1371/journal.ppat.1002005.
24. Ross AL, Cannou C, Barre-Sinoussi F, Menu E, (2009) Proteasome-independent degradation of HIV-1 in naturally non-permissive human placental trophoblast cells. Retrovirology 6: 46.
25. Vidricaire G, Tremblay MJ, (2005) Rab5 and Rab7, but not ARF6, govern the early events of HIV-1 infection in polarized human placental cells. J Immunol 175: 6517-6530.
26. King AE, Paltoo A, Kelly RW, Sallenave JM, Bocking AD, et al. (2007) Expression of natural antimicrobials by human placenta and fetal membranes. Placenta 28: 161-169.
27. Onderdonk AB, Hecht JL, McElrath TF, Delaney ML, Allred EN, et al. (2008) Colonization of second-trimester placenta parenchyma. Am Journal Obstet Gynecol 199: 52 e51-52.e10.
28. Pereira L, Maidji E, McDonagh S, Genbacev O, Fisher S, (2003) Human cytomegalovirus transmission from the uterus to the placenta correlates with the presence of pathogenic bacteria and maternal immunity. J Virol 77: 13301-13314.
29. Cardenas I, Means RE, Aldo P, Koga K, Lang SM, et al. (2010) Viral infection of the placenta leads to fetal inflammation and sensitization to bacterial products predisposing to preterm labor. J Immunol 185: 1248-1257.
30. Fried M, Duffy PE, (1996) Adherence of Plasmodium falciparum to chondroitin sulfate A in the human placenta. Science 272: 1502-1504.
31. Crocker IP, Tanner OM, Myers JE, Bulmer JN, Walraven G, et al. (2004) Syncytiotrophoblast degradation and the pathophysiology of the malaria-infected placenta. Placenta 25: 273-282.
32. Bulterys PL, Chao A, Dalai SC, Zink MC, Dushimimana A, et al. (2011) Placental malaria and mother-to-child transmission of human immunodeficiency virus-1 in rural Rwanda. Am J Trop Med Hyg 85: 202-206.