Synthesis, evaluation of 6,8-dibromo-2-aryl-2,3-dihydroquinolin-4(1H)-ones in MCF-7 (breast cancer) cell lines and their docking studies

Medicinal Chemistry Research

Volumn 21, Issue 8, 2012, Pages 1741-1750

  Bheemanapalli, Lakshmi Narayana ^a   Kaur, Amandeep ^a   Arora, Ramandish ^a   Sangeeta, ^a   Akkinepally, Raghuram Rao ^a   Javali, Narashima Murthy ^b  

^a PANJAB UNIVERSITY   (India)

^b UNIVERSITY OF THE PACIFIC   (United States)

Author keywords

Dihydroquinolin 4(1H) ones; Docking studies; MCF 7 cell line; Nonsteroidal aromatase inhibitors

Indexed keywords

1 (2 AMINO 3,5 DIBROMOPHENYL) 3 (4 BROMOPHENYL) PROP 2 EN 1 ONE; 1 (2 AMINO 3,5 DIBROMOPHENYL) 3 (4 CHLOROPHENYL) PROP 2 EN 1 ONE; 1 (2 AMINO 3,5 DIBROMOPHENYL) 3 (4 FLUOROPHENYL) PROP 2 EN 1 ONE; 1 (2 AMINO 3,5 DIBROMOPHENYL) 3 (4 HYDROXYPHENYL) PROP 2 EN 1 ONE; 1 (2 AMINO 3,5 DIBROMOPHENYL) 3 (4 NITROPHENYL) PROP 2 EN 1 ONE; 1 (2 AMINO 3,5 DIBROMOPHENYL) 3 (4HYDROXYPHENYL) PROP 2 EN 1 ONE; 1 (2 AMINO 3,5 DIBROMOPHENYL) 3 (4METHOXYPHENYL) PROP 2 EN 1 ONE; 1 (2 AMINO 3,5 DIBROMOPHENYL) 3 (DIMETHYLAMINO) PHENYL) PROP 2 EN 1 ONE; 1 (2 AMINO 3,5 DIBROMOPHENYL) 3 (TRIMETHOXYPHENYL) PROP 2 EN 1 ONE; 1 (2 AMINO 3,5 DIBROMOPHENYL) ETHANONE; 4 (6,8 DIBROMO 4 OXO 1,2,3,4 TETRAHYDROQUINOLIN 2 YL) BENZONITRILE; 6,8 DIBROMO 2 (3 HYDROXYPHENYL) 2,3 DIHYDROQUINOLIN 4 (1H) ONE; 6,8 DIBROMO 2 (3,4,5 TRIMETHOXYPHENYL) 2,3 DIHYDROQUINOLIN 4 (1H) ONE; 6,8 DIBROMO 2 (4 BROMOPHENYL) 2,3 DIHYDROQUINOLIN 4(1H) ONE; 6,8 DIBROMO 2 (4 CHLOROPHENYL) 2,3 DIHYDROQUINOLIN 4(1H) ONE; 6,8 DIBROMO 2 (4 FLUOROPHENYL) 2,3 DIHYDROQUINOLIN 4(1H) ONE; 6,8 DIBROMO 2 (4 HYDROXYPHENYL) 2,3 DIHYDROQUINOLIN 4 (1H) ONE; 6,8 DIBROMO 2 (4 METHOXYPHENYL) 2,3 DIHYDROQUINOLIN 4 (1H) ONE; 6,8 DIBROMO 2 (4 NITROPHENYL) 2,3 DIHYDROQUINOLIN 4(1H) ONE; 6,8 DIBROMO 2 ARYL 2,3 DIHYDROQUINOLIN 4 (1H) ONE; 6,8 DIBROMO 2 ARYL 2,3 DIHYDROQUINOLIN 4 (1H) ONE DERIVATIVE; ANTINEOPLASTIC AGENT; LEVO PROLINE CATALYZED CYCLIZATION OF 1 (2 AMINO 3,5 DIBROMOPHENYL) ETHANOL; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL STRAIN MCF 7; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY;

EID: 84866134730     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-011-9688-z     Document Type: Article

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