Systematic review of intravenous methylene blue in parathyroid surgery

British Journal of Surgery

Volumn 99, Issue 10, 2012, Pages 1345-1351

  Patel, H P ^a   Chadwick, D R ^b   Harrison, B J ^c   Balasubramanian, S P ^a,c  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b CHESTERFIELD ROYAL HOSPITAL NHS FOUNDATION TRUST   (United Kingdom)

^c SHEFFIELD TEACHING HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COLORING AGENT; DIAGNOSTIC AGENT; METHYLENE BLUE;

HUMAN; INTRAVENOUS DRUG ADMINISTRATION; LABORATORY DIAGNOSIS; METHODOLOGY; OPERATION DURATION; PARATHYROID DISEASE; PARATHYROIDECTOMY; REVIEW; TREATMENT OUTCOME;

COLORING AGENTS; FALSE POSITIVE REACTIONS; HUMANS; INFUSIONS, INTRAVENOUS; METHYLENE BLUE; OPERATIVE TIME; PARATHYROID DISEASES; PARATHYROIDECTOMY; TREATMENT OUTCOME;

EID: 84866111134     PISSN: 00071323     EISSN: 13652168     Source Type: Journal    
DOI: 10.1002/bjs.8814     Document Type: Review

References (48)

1. Dudley NE,. Methylene blue for rapid identification of the parathyroids. Br Med J 1971; 3: 680-681.
2. Bambach CP, Reeve TS,. Parathyroid identification by methylene blue infusion. Aust N Z J Surg 1978; 48: 314-317.
3. Derom AF, Wallaert PC, Janzing HM, Derom FE,. Intraoperative identification of parathyroid glands with methylene blue infusion. Am J Surg 1993; 165: 380-382.
4. Gavilán J, Gavilán C, Tomás MD,. Methylene blue infusion for intraoperative identification of the parathyroid glands. Laryngoscope 1986; 96: 1389-1390.
5. Gordon DL, Airan MC, Thomas W, Seidman LH,. Parathyroid identification by methylene blue infusion. Br J Surg 1975; 62: 747-749.
6. Orloff LA,. Methylene blue and sestamibi: complementary tools for localizing parathyroids. Laryngoscope 2001; 111: 1901-1904.
7. Harrison BJ, Triponez F,. Intraoperative adjuncts in surgery for primary hyperparathyroidism. Langenbecks Arch Surg 2009; 394: 799-809.
8. Gillman PK,. Methylene blue implicated in potentially fatal serotonin toxicity. Anaesthesia 2006; 61: 1013-1014.
9. Patel AS, Singh-Ranger D, Lowery KA, Crinnion JN,. Adverse neurologic effect of methylene blue used during parathyroidectomy. Head Neck 2006; 28: 567-568.
10. Khavandi A, Whitaker J, Gonna H,. Serotonin toxicity precipitated by concomitant use of citalopram and methylene blue. Med J Aust 2008; 189: 534-535.
11. Rowley M, Riutort K, Shapiro D, Casler J, Festic E, Freeman WD,. Methylene blue-associated serotonin syndrome: a 'green' encephalopathy after parathyroidectomy. Neurocrit Care 2009; 11: 88-93.
12. Pollack G, Pollack A, Delfiner J, Fernandez J,. Parathyroid surgery and methylene blue: a review with guidelines for safe intraoperative use. Laryngoscope 2009; 119: 1941-1946.
13. Baloch MN, Aslam T, Maher M,. Surgical management of hyperparathyroidism. J Coll Physicians Surg Pak 2007; 17: 683-685.
14. Han N, Bumpous JM, Goldstein RE, Fleming MM, Flynn MB,. Intra-operative parathyroid identification using methylene blue in parathyroid surgery. Am Surg 2007; 73: 820-823.
15. 99mTc-MIBI scintigram. Endocr J 2007; 54: 437-440.
16. Khan MA, North AP, Chadwick DR,. Prolonged postoperative altered mental status after methylene blue infusion during parathyroidectomy: a case report and review of the literature. Ann R Coll Surg Engl 2007; 89: W9-W11.
17. Sweet G, Standiford SB,. Methylene-blue-associated encephalopathy. J Am Coll Surg 2007; 204: 454-458.
18. Ng BK, Cameron AJ, Liang R, Rahman H,. [Serotonin syndrome following methylene blue infusion during parathyroidectomy: a case report and literature review.] Can J Anesth 2008; 55: 36-41.
19. Mihai R, Gleeson F, Buley ID, Roskell DE, Sadler GP,. Negative imaging studies for primary hyperparathyroidism are unavoidable: correlation of sestamibi and high-resolution ultrasound scanning with histological analysis in 150 patients. World J Surg 2006; 30: 697-704.
20. Mathew S, Linhartova L, Raghuraman G,. Hyperpyrexia and prolonged postoperative disorientation following methylene blue infusion during parathyroidectomy. Anaesthesia 2006; 61: 580-583.
21. Alexander TH, Beros AD, Orloff LA,. Twice-recurrent primary hyperparathyroidism due to parathyroid hyperplasia in an ectopic supernumerary gland. Endocr Pract 2006; 12: 165-169.
22. Majithia A, Stearns MP,. Methylene blue toxicity following infusion to localize parathyroid adenoma. J Laryngol Otol 2006; 120: 138-140.
23. Kuriloff DB, Sanborn KV,. Rapid intraoperative localization of parathyroid glands utilizing methylene blue infusion. Otolaryngol Head Neck Surg 2004; 131: 616-622.
24. Soomro MS, Moizuddin,. Role of methylene blue infusion in per-operative localization of parathyroid glands. J Pak Med Assoc 2004; 54: 199-202.
25. Bach KK, Lindsay FW, Berg LS, Howard RS,. Prolonged postoperative disorientation after methylene blue infusion during parathyroidectomy. Anesth Analg 2004; 99: 1573-1574.
26. Chandran M, Deftos LJ, Stuenkel CA, Haghighi P, Orloff LA,. Thymic parathyroid carcinoma and postoperative hungry bone syndrome. Endocr Pract 2003; 9: 152-156.
27. Schell SR, Dudley NE,. Clinical outcomes and fiscal consequences of bilateral neck exploration for primary idiopathic hyperparathyroidism without preoperative radionuclide imaging or minimally invasive techniques. Surgery 2003; 133: 32-39.
28. Flynn MB, Bumpous JM, Schill K, McMasters KM,. Minimally invasive radioguided parathyroidectomy. J Am Coll Surg 2000; 191: 24-31.
29. Martin RC II, Greenwell D, Flynn MB,. Initial neck exploration for untreated hyperparathyroidism. Am Surg 2000; 66: 269-272.
30. Takei H, Iino Y, Endo K, Horiguchi J, Maemura M, Koibuchi Y, et al., The efficacy of technetium-99m-MIBI scan and intraoperative methylene blue staining for the localization of abnormal parathyroid glands. Surg Today 1999; 29: 307-312.
31. Stanford BJ, Stanford SC,. Postoperative delirium indicating an adverse drug interaction involving the selective serotonin reuptake inhibitor, paroxetine? J Psychopharmacol 1999; 13: 313-317.
32. Horii Y, Iino Y, Maemura M, Takei H, Horiguchi J, Koibuchi Y, et al., Usefulness of technetium-99m-methoxyisobutylisonitrile imaging and intraoperative staining technique using methylene blue for localization: two cases of hyperfunctioning parathyroid lesions. Kitakanto Medical Journal 1998; 48: 367-371.
33. Müslümanoǧlu M, Terzioǧlu T, Ozarmaǧan S, Tezelman S, Güloǧlu R,. Comparison of preoperative imaging techniques (thallium technetium scan and ultrasonography) and intraoperative staining (with methylene blue) in localizing the parathyroid glands. Radiol Med 1995; 90: 444-447.
34. O'Leary DP, White HJ,. Parathyroidectomy for hyperparathyroidism associated with renal disease. Ann R Coll Surg Engl 1995; 77: 97-101.
35. Kobayashi S, Miyakawa M, Sugenoya A, Senga O, Kaneko G, Yokozawa T, et al., An evaluation of the intraoperative staining technique using methylene blue for the detection of hyperplastic parathyroid glands. Jpn J Surg 1988; 18: 729-731.
36. Bland KI, Tidwell S, von Fraunhofer JA, Morris RR, McCoy MT, Wathen RL,. Intraoperative localization of parathyroid glands using methylthionine chloride/tetramethylthionine chloride in secondary hyperparathyroidism. Surg Gynecol Obstet 1985; 160: 42-48.
37. Botha JR, Diamond TH, Meyers AM, Myburgh JA,. Parathyroid disease. Part I. The management of primary hyperparathyroidism. S Afr J Surg 1985; 23: 43-46.
38. Sherlock DJ, Holl-Allen RT,. Intravital methylene blue staining of parathyroid glands and tumours. Ann R Coll Surg Engl 1984; 66: 396-398.
39. Devine RM, van Heerden JA, Grant CS, Muir JJ,. The role of methylene blue infusion in the management of persistent or recurrent hyperparathyroidism. Surgery 1983; 94: 916-918.
40. Wheeler MH, Wade JS,. Intraoperative identification of parathyroid glands: appraisal of methylene blue staining. Am J Surg 1982; 143: 713-716.
41. Lavelle MA,. Parathyroid adenoma stained with methylene blue. J R Soc Med 1980; 73: 462-463.
42. Cox RJ, Moore DB, Wolfman EF Jr,. Localization of the parathyroid glands by intraoperative methylene blue staining. Surg Gynecol Obstet 1979; 148: 769-770.
43. Drews M, Paszkowski J, Stawny B, Banasiewicz T, Hermann J, MeczyÅski M, et al., Comparison of parathyroid gland localization techniques in patients treated due to gland hyperfunction. Polski Przeglad Chirurgiczny 2003; 75: 821-828.
44. Martindale SJ, Stedeford JC,. Neurological sequelae following methylene blue injection for parathyroidectomy. Anaesthesia 2003; 58: 1041-1042.
45. Ramsay RR, Dunford C, Gillman PK,. Methylene blue and serotonin toxicity: inhibition of monoamine oxidase A (MAO A) confirms a theoretical prediction. Br J Pharmacol 2007; 152: 946-951.
46. Bodner RA, Lynch T, Lewis L, Khan D,. Serotonin syndrome. Neurology 1995; 45: 219-223.
47. Ng BKW, Cameron AJ,. The role of methylene blue in serotonin syndrome: a systematic review. Psychosomatics 2010; 51: 194-200.
48. Medicines and Healthcare products Regulatory Agency. Methythioninium chloride (methylene blue): CNS toxicity with serotonergic drugs. Drug Safety Update 2008; 1: 5.