SLC2A2 mutations can cause neonatal diabetes, suggesting GLUT2 may have a role in human insulin secretion

Diabetologia

Volumn 55, Issue 9, 2012, Pages 2381-2385

  Sansbury, F H ^a,b   Flanagan, S E ^a   Houghton, J A L ^a,b   Shuixian Shen, F L ^c   Al Senani, A M S ^d   Habeb, A M ^e   Abdullah, M ^f   Kariminejad, A ^g   Ellard, S ^a,b   Hattersley, A T ^a,b  

^a UNIVERSITY OF EXETER   (United Kingdom)

^b ROYAL DEVON AND EXETER NHS FOUNDATION TRUST   (United Kingdom)

^c FUDAN UNIVERSITY   (China)

^d ROYAL HOSPITAL   (Oman)

^e Maternity and Children Hospital   (Saudi Arabia)

^f UNIVERSITY OF KHARTOUM   (Sudan)

^g Kariminejad Najmabadi Pathology and Genetics Center   (Iran)

Author keywords

Fanconi Bickel syndrome; FBS; GLUT2; Neonatal diabetes mellitus; Permanent neonatal diabetes mellitus; PNDM; SLC2A2; TNDM; Transient neonatal diabetes mellitus

Indexed keywords

GLIBENCLAMIDE; GLUCOSE TRANSPORTER 2; INSULIN; PRIMER DNA; SLC2A2 PROTEIN, HUMAN;

ARTICLE; CLINICAL FEATURE; COHORT ANALYSIS; DIABETES MELLITUS; DIABETOGENESIS; DISORDERS OF CARBOHYDRATE METABOLISM; FANCONI BICKEL SYNDROME; FEMALE; GENE; GENE MAPPING; GENE MUTATION; GENETIC ASSOCIATION; HOMOZYGOSITY; HUMAN; INSULIN RELEASE; MAJOR CLINICAL STUDY; MALE; MOLECULAR PATHOLOGY; NEWBORN; NEWBORN DISEASE; NUCLEOTIDE SEQUENCE; PANCREAS ISLET BETA CELL; PERMANENT NEONATAL DIABETES MELLITUS; PRIORITY JOURNAL; PROTEIN FUNCTION; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; SLC2A2 GENE; TRANSIENT NEONATAL DIABETES MELLITUS; FANCONI SYNDROME; GENETICS; MUTATION; SECRETION (PROCESS);

BASE SEQUENCE; CARBOHYDRATE METABOLISM, INBORN ERRORS; DIABETES MELLITUS; DNA PRIMERS; FANCONI SYNDROME; FEMALE; GLUCOSE TRANSPORTER TYPE 2; HUMANS; INFANT, NEWBORN; INSULIN; MALE; MUTATION;

EID: 84866085184     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-012-2595-0     Document Type: Article

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