Human herpesvirus 6 and 7 in febrile status epilepticus: The FEBSTAT study

Epilepsia

Volumn 53, Issue 9, 2012, Pages 1481-1488

  Epstein, Leon G ^a   Shinnar, Shlomo ^b   Hesdorffer, Dale C ^c   Nordli, Douglas R ^a   Hamidullah, Aaliyah ^d   Benn, Emma K T ^c   Pellock, John M ^e   Frank, L Matthew ^f   Lewis, Darrell V ^g   Moshe, Solomon L ^b   Shinnar, Ruth C ^h   Sun, Shumei ^e  

^a NORTHWESTERN UNIVERSITY   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c Vagelos College of Physicians and Surgeons   (United States)

^d CHILDREN S MEMORIAL RESEARCH CENTER   (United States)

^e VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^f EASTERN VIRGINIA MEDICAL SCHOOL   (United States)

^g DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^h MONTEFIORE MEDICAL CENTER   (United States)

Author keywords

Febrile seizures; Human herpesvirus; Mesial temporal sclerosis; Status epilepticus

Indexed keywords

ANTIBODY TITER; CHILD; CONTROLLED STUDY; DISEASE ASSOCIATION; EEG ABNORMALITY; EPILEPTIC STATE; FEBRILE CONVULSION; FEMALE; HERPES VIRUS INFECTION; HIPPOCAMPUS; HUMAN; HUMAN HERPESVIRUS 6; HUMAN HERPESVIRUS 7; INFANT; MAJOR CLINICAL STUDY; MALE; MIXED INFECTION; MULTICENTER STUDY; PHENOMENOLOGY; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; PRIMARY INFECTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUANTITATIVE ASSAY; REVIEW; RISK; TEMPORAL LOBE EPILEPSY; VIRUS REACTIVATION;

CHILD, PRESCHOOL; FEMALE; HERPESVIRUS 6, HUMAN; HERPESVIRUS 7, HUMAN; HUMANS; INFANT; INFANT, NEWBORN; MALE; PROSPECTIVE STUDIES; ROSEOLOVIRUS INFECTIONS; SEIZURES, FEBRILE; STATUS EPILEPTICUS;

EID: 84866076485     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2012.03542.x     Document Type: Review

References (46)

1. Aicardi J, Chevrie JJ,. (1970) Convulsive status epilepticus in infants and children. A study of 239 cases. Epilepsia 11: 187-197.
2. Berg AT, Shinnar S, Shapiro ED, Salomon ME, Crain EF, Hauser WA,. (1995) Risk factors for a first febrile seizure: a matched case-control study. Epilepsia 36: 334-341.
3. Boutolleau D, Bonduelle O, Sabard A, Devers L, Agut H, Gautheret-Dejean A,. (2005) Detection of human herpesvirus 7 DNA in peripheral blood reflects mainly CD4+ cell count in patients infected with HIV. J Med Virol 76: 223-228.
4. Boutolleau D, Duros C, Bonnafous P, Caiola D, Karras A, Castro ND, Ouachee M, Narcy P, Gueudin M, Agut H, Gautheret-Dejean A,. (2006) Identification of human herpesvirus 6 variants A and B by primer-specific real-time PCR may help to revisit their respective role in pathology. J Clin Virol 35: 257-263.
5. Caserta MT, Hall CB, Schnabel K, Long CE, D'Heron N,. (1998) Primary human herpesvirus 7 infection: a comparison of human herpesvirus 7 and human herpesvirus 6 infections in children. J Pediatr 133: 386-389.
6. Caserta MT, McDermott MP, Dewhurst S, Schnabel K, Carnahan JA, Gilbert L, Lathan G, Lofthus GK, Hall CB,. (2004) Human herpesvirus 6 (HHV6) DNA persistence and reactivation in healthy children. J Pediatr 145: 478-484.
7. Caserta MT, Hall CB, Schnabel K, Lofthus G, Marino A, Shelley L, Yoo C, Carnahan J, Anderson L, Wang H,. (2010) Diagnostic assays for active infection with human herpesvirus 6 (HHV-6). J Clin Virol 48: 55-57.
8. Cermelli C, Fabio G, Montorsi M, Sabbatini AM, Portolani M,. (1996) Prevalence of antibodies to human herpesviruses 6 and 7 in early infancy and age at primary infection. New Microbiol 19: 1-8.
9. Chin RF, Neville BG, Peckham C, Bedford H, Wade A, Scott RC,. (2006) Incidence, cause, and short-term outcome of convulsive status epilepticus in childhood: prospective population-based study. Lancet 368: 222-229.
10. Clark DA, Freeland ML, Mackie LK, Jarrett RF, Onions DE,. (1993) Prevalence of antibody to human herpesvirus 7 by age. J Infect Dis 168: 251-252.
11. Commission on Epidemiology and Prognosis, International League Against Epilepsy. (1993) Guidelines for Epidemiologic Studies on Epilepsy. Epilepsia 34: 592-596.
12. Dewhurst S, McIntyre K, Schnabel K, Hall CB,. (1993) Human herpesvirus 6 (HHV-6) variant B accounts for the majority of symptomatic primary HHV-6 infections in a population of U.S. infants. J Clin Microbiol 31: 416-418.
13. Dodson WE, DeLorenzo RJ, Pedley TA, Shinnar S, Treiman DM, Wannamaker BB,. (1993) The treatment of convulsive status epilepticus: Recommendations of the Epilepsy Foundation of America's working group on status epilepticus. JAMA 270: 854-859.
14. Donati D, Akhyani N, Fogdell-Hahn A, Cermelli C, Cassiani-Ingoni R, Vortmeyer A, Heiss JD, Cogen P, Gaillard WD, Sato S, Theodore WH, Jacobson S,. (2003) Detection of human herpesvirus-6 in mesial temporal lobe epilepsy surgical brain resections. Neurology 61: 1405-1411.
15. Donati D, Martinelli E, Cassiani-Ingoni R, Ahlqvist J, Hou J, Major EO, Jacobson S,. (2005) Variant-specific tropism of human herpesvirus 6 in human astrocytes. J Virol 79: 9439-9448.
16. Ellenberg JH, Nelson KB,. (1980) Sample selection and the natural history of disease. Studies of febrile seizures. JAMA 243: 1337-1340.
17. Fotheringham J, Donati D, Akhyani N, Fogdell-Hahn A, Vortmeyer A, Heiss JD, Williams E, Weinstein S, Bruce DA, Gaillard WD, Sato S, Theodore WH, Jacobson S,. (2007) Association of human herpesvirus-6B with mesial temporal lobe epilepsy. PLoS Med 4: e180.
18. French JA, Williamson PD, Thadani VM, Darcey TM, Mattson RH, Spencer SS, Spencer DD,. (1993) Characteristics of medial temporal lobe epilepsy: I. Results of history and physical examination. Ann Neurol 34: 774-780.
19. Fujiwara T, Ishida S, Miyakoshi M, Sakuma N, Moriyama S, Morikawa T, Seino M, Wada T,. (1979) Status epilepticus in childhood: a retrospective study of initial convulsive status and subsequent epilepsies. Folia Psychiatr Neurol Jpn 33: 337-344.
20. Hall CB, Long CE, Schnabel KC, Caserta MT, McIntyre KM, Costanzo MA, Knott A, Dewhurst S, Insel RA, Epstein LG,. (1994) Human herpesvirus-6 infection in children. A prospective study of complications and reactivation. N Engl J Med 331: 432-438.
21. Hall CB, Caserta MT, Schnabel KC, McDermott MP, Lofthus GK, Carnahan JA, Gilbert LM, Dewhurst S,. (2006) Characteristics and acquisition of human herpesvirus (HHV) 7 infections in relation to infection with HHV-6. J Infect Dis 193: 1063-1069.
22. Hesdorffer DC, Logroscino G, Cascino G, Annegers JF, Hauser WA,. (1998) Incidence of status epilepticus in Rochester, Minnesota, 1965-1984. Neurology 50: 735-741.
23. Hesdorffer DC, Benn EK, Bagiella E, Nordli D, Pellock J, Hinton V, Shinnar S,. (2011) Distribution of febrile seizure duration and associations with development. Ann Neurol 70: 93-100.
24. Ichiyama T, Suenaga N, Kajimoto M, Tohyama J, Isumi H, Kubota M, Mori M, Furukawa S,. (2008) Serum and CSF levels of cytokines in acute encephalopathy following prolonged febrile seizures. Brain Dev 30: 47-52.
25. Ichiyama T, Ito Y, Kubota M, Yamazaki T, Nakamura K, Furukawa S,. (2009) Serum and cerebrospinal fluid levels of cytokines in acute encephalopathy associated with human herpesvirus-6 infection. Brain Dev 31: 731-738.
26. Lewis DV, Barboriak DP, MacFall JR, Provenzale JM, Mitchell TV, VanLandingham KE,. (2002) Do prolonged febrile seizures produce medial temporal sclerosis? Hypotheses, MRI evidence and unanswered questions. Prog Brain Res 135: 263-278.
27. Mannonen L, Herrgard E, Valmari P, Rautiainen P, Uotila K, Aine MR, Karttunen-Lewandowski P, Sankala J, Wallden T, Koskiniemi M,. (2007) Primary human herpesvirus-6 infection in the central nervous system can cause severe disease. Pediatr Neurol 37: 186-191.
28. Mathern GW, Pretorius JK, Babb TL,. (1995) Influence of the type of initial precipitating injury and at what age it occurs on course and outcome in patients with temporal lobe seizures. J Neurosurg 82: 220-227.
29. McClelland S, Dube CM, Yang J, Baram TZ,. (2011) Epileptogenesis after prolonged febrile seizures: mechanisms, biomarkers and therapeutic opportunities. Neurosci Lett 497: 155-162.
30. National Institutes of Health. (1980) Febrile seizures: consensus development conference summary. Vol 3, No. 2. National Institutes of Health, Bethesda, MD.
31. Nishiyama I, Ohtsuka Y, Tsuda T, Inoue H, Kunitomi T, Shiraga H, Kimura T, Fujimoto K,. (2007) An epidemiological study of children with status epilepticus in Okayama, Japan. Epilepsia 48: 1133-1137.
32. Norton RA, Caserta MT, Hall CB, Schnabel K, Hocknell P, Dewhurst S,. (1999) Detection of human herpesvirus 6 by reverse transcription-PCR. J Clin Microbiol 37: 3672-3675.
33. Provenzale JM, Barboriak DP, VanLandingham K, MacFall J, Delong D, Lewis DV,. (2008) Hippocampal MRI signal hyperintensity after febrile status epilepticus is predictive of subsequent mesial temporal sclerosis. AJR Am J Roentgenol 190: 976-983.
34. Sadarangani M, Seaton C, Scott JA, Ogutu B, Edwards T, Prins A, Gatakaa H, Idro R, Berkley JA, Peshu N, Neville BG, Newton CR,. (2008) Incidence and outcome of convulsive status epilepticus in Kenyan children: a cohort study. Lancet Neurol 7: 145-150.
35. Scott RC, Gadian DG, King MD, Chong WK, Cox TC, Neville BG, Connelly A,. (2002) Magnetic resonance imaging findings within 5 days of status epilepticus in childhood. Brain 125: 1951-1959.
36. Scott RC, King MD, Gadian DG, Neville BG, Connelly A,. (2003) Hippocampal abnormalities after prolonged febrile convulsion: a longitudinal MRI study. Brain 126: 2551-2557.
37. Shinnar S,. (2003) Febrile seizures and mesial temporal sclerosis. Epilepsy Curr 3: 115-118.
38. Shinnar S, Pellock JM, Moshe SL, Maytal J, O'Dell C, Driscoll SM, Alemany M, Newstein D, DeLorenzo RJ,. (1997) In whom does status epilepticus occur: age-related differences in children. Epilepsia 38: 907-914.
39. Shinnar S, Hesdorffer DC, Nordli DR Jr, Pellock JM, O'Dell C, Lewis DV, Frank LM, Moshe SL, Epstein LG, Marmarou A, Bagiella E,. (2008) Phenomenology of prolonged febrile seizures: results of the FEBSTAT study. Neurology 71: 170-176.
40. VanLandingham KE, Heinz ER, Cavazos JE, Lewis DV,. (1998) Magnetic resonance imaging evidence of hippocampal injury after prolonged focal febrile convulsions. Ann Neurol 43: 413-426.
41. Wainwright MS, Martin PL, Morse RP, Lacaze M, Provenzale JM, Coleman RE, Morgan MA, Hulette C, Kurtzberg J, Bushnell C, Epstein L, Lewis DV,. (2001) Human herpesvirus 6 limbic encephalitis after stem cell transplantation. Ann Neurol 50: 612-619.
42. Ward KN, Andrews NJ, Verity CM, Miller E, Ross EM,. (2005) Human herpesviruses-6 and -7 each cause significant neurological morbidity in Britain and Ireland. Arch Dis Child 90: 619-623.
43. Waterhouse EJ, Garnett LK, Towne AR, Morton LD, Barnes T, Ko D, DeLorenzo RJ,. (1999) Prospective population-based study of intermittent and continuous convulsive status epilepticus in Richmond, Virginia. Epilepsia 40: 752-758.
44. Yamanishi K, Okuno T, Shiraki K, Takahashi M, Kondo T, Asano Y, Kurata T,. (1988) Identification of human herpesvirus-6 as a causal agent for exanthem subitum. Lancet 1: 1065-1067.
45. Zerr DM, Huang ML, Corey L, Erickson M, Parker HL, Frenkel LM,. (2000) Sensitive method for detection of human herpesviruses 6 and 7 in saliva collected in field studies. J Clin Microbiol 38: 1981-1983.
46. Zerr DM, Gupta D, Huang ML, Carter R, Corey L,. (2002) Effect of antivirals on human herpesvirus 6 replication in hematopoietic stem cell transplant recipients. Clin Infect Dis 34: 309-317.