Mapping of the CD23 binding site on immunoglobulin e (IgE) and allosteric control of the IgE-FcεRI interaction

Journal of Biological Chemistry

Volumn 287, Issue 37, 2012, Pages 31457-31461

  Borthakur, Susmita ^a,c   Hibbert, Richard G ^b,d   Pang, Marie O Y ^a   Yahya, Norhakim ^a   Bax, Heather J ^a   Kao, Michael W ^a   Cooper, Alison M ^a   Beavil, Andrew J ^a   Sutton, Brian J ^a   Gould, Hannah J ^a   McDonnell, James M ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGIC RESPONSE; ALLOSTERIC CONTROL; ALLOSTERIC MECHANISMS; B CELLS; CELLULAR RECEPTORS; DEGREE OF AUTONOMY; EXPRESSION LEVELS; FC REGION; IMMUNOGLOBULIN E; INTERACTION SITE; MAST CELLS; NMR CHEMICAL SHIFTS; PROTEIN NETWORK; RECEPTOR BINDING; SITE DIRECTED MUTAGENESIS;

BIOCHEMISTRY; BIOLOGY;

BINDING SITES;

CD23 ANTIGEN; FC EPSILON RECEPTOR I; FC RECEPTOR; IMMUNOGLOBULIN E; UNCLASSIFIED DRUG;

ALLOSTERISM; ANTIBODY COMBINING SITE; ANTIGEN ANTIBODY REACTION; ANTIGEN EXPRESSION; ARTICLE; B LYMPHOCYTE; BASOPHIL; CELL ACTIVATION; CONTROLLED STUDY; CROSS LINKING; HUMAN; HUMAN CELL; MAST CELL; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FUNCTION; SITE DIRECTED MUTAGENESIS;

ALLOSTERIC REGULATION; BASOPHILS; CELL LINE; HUMANS; IMMUNOGLOBULIN E; MAST CELLS; MUTAGENESIS, SITE-DIRECTED; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDE MAPPING; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, IGE;

EID: 84866072439     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.C112.397059     Document Type: Article

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