Biodegradable polymersomes with an ionizable membrane: Facile preparation, superior protein loading, and endosomal pH-responsive protein release

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 82, Issue 1, 2012, Pages 103-111

  Li, Shaoke ^a   Meng, Fenghua ^a   Wang, Zhongjuan ^a   Zhong, Yinan ^a   Zheng, Meng ^a   Liu, Haiyan ^a   Zhong, Zhiyuan ^a  

^a SOOCHOW UNIVERSITY   (China)

Author keywords

Biodegradable; Cancer therapy; Ionizable membrane; pH sensitive; Polymersomes; Protein delivery

Indexed keywords

BOVINE SERUM ALBUMIN; COPOLYMER; CYTOCHROME C; MEMBRANE IONIZABLE BIODEGRADABLE POLYMERSOME; NANOCARRIER; POLY(ETHYLENE GLYCOL) B POLY(TRIMETHYLENE CARBONATE); UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL PH; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; ELECTRON TRANSPORT; ENDOSOME; ENZYME ACTIVITY; FLOW CYTOMETRY; IN VITRO STUDY; INTRACELLULAR SPACE; PARTICLE SIZE; PH; PROTEIN SECRETION; ROOM TEMPERATURE; SYNTHESIS;

APOPTOSIS; CYTOCHROMES C; DIOXANES; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; ENDOSOMES; FLOW CYTOMETRY; FLUORESCEIN-5-ISOTHIOCYANATE; HELA CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; MCF-7 CELLS; MICROSCOPY, CONFOCAL; NANOPARTICLES; POLYETHYLENE GLYCOLS; POLYMERS; SERUM ALBUMIN, BOVINE; TEMPERATURE; TIME FACTORS;

EID: 84866024104     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2012.05.009     Document Type: Article

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