An interleukin-10 gene promoter polymorphism (2592A/C) associated with type 2 diabetes: A North Indian study

Biochemical Genetics

Volumn 50, Issue 7-8, 2012, Pages 549-559

  Saxena, Madhukar ^a   Agrawal, C G ^b   Bid, Hemant Kumar ^c   Banerjee, Monisha ^a  

^a UNIVERSITY OF LUCKNOW   (India)

^b KING GEORGE'S MEDICAL UNIVERSITY   (India)

^c THE RESEARCH INSTITUTE AT NATIONWIDE CHILDREN S HOSPITAL   (United States)

Author keywords

ELISA; Interleukin 10; North Indian population; PCR RFLP; SNP; Type 2 diabetes mellitus

Indexed keywords

ADENOSINE; CYTIDINE; GLUCOSE; INTERLEUKIN 10;

ADULT; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE; GENE FREQUENCY; GENETIC ASSOCIATION; GENOTYPE; GLUCOSE BLOOD LEVEL; HETEROZYGOTE; HUMAN; INDIAN; INTERLEUKIN 10 GENE; MAJOR CLINICAL STUDY; NON INSULIN DEPENDENT DIABETES MELLITUS; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; BASE SEQUENCE; CASE-CONTROL STUDIES; DIABETES MELLITUS, TYPE 2; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENOTYPE; HUMANS; INDIA; INTERLEUKIN-10; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC;

EID: 84866004134     PISSN: 00062928     EISSN: 15734927     Source Type: Journal    
DOI: 10.1007/s10528-012-9499-z     Document Type: Article

References (26)

1. American Diabetes Association (2010) Screening for type 2 diabetes. Diabetes Care 33:S1
2. Chang YH, Huang CN, Wu CY, Shiau MY (2005) Association of interleukin-10 A-592C and T-819C polymorphisms with type 2 diabetes mellitus. Hum Immunol 66:1258-1263
3. D'Alfonso S, Rampi M, Bocchio D, Colombo G, Scorza-Smeraldi R, Momigliano-Richardi P (2000) Systemic lupus erythematosus candidate genes in the Italian population: evidence for a significant association with interleukin-10. Arthritis Rheum 43:120-128
4. Edwards-Smith CJ, Jonsson JR, Purdie DM, Bansal A, Shorthouse C, Powell EE (1999) Interleukin-10 promoter polymorphism predicts initial response of chronic hepatitis C to interferon a. Hepatology 30:526-530
5. Eskdale J, Gallagher G, Verweij CL, Keijsers V, Westendrotp RG, Huizinga TW (1998) Interleukin 10 secretion in relation to human IL-10 locus haplotypes. Proc Natl Acad Sci USA 95:9465-9470
6. Forte GI, Pilato G, Vaccarino L, Sanacore M, Candore G, Romano GC, Testa R, Franceschi C, Capri M, Marra M, Bonfigli AR, Caruso C, Scola L, Lio D (2010) Risk profile in type 2 diabetes (metabolic syndrome): integration of IL-10 polymorphisms and laboratory parameters to identify vascular damage related complications. Curr Pharm Des 16:898-903
7. Hong EG, Ko HJ, Cho YR, Kim HJ, Ma Z, Yu TY, Friedline RH, Kurt-Jones E, Finberg R, Fischer MA, Granger EL, Norbury CC, Hauschka SD, Philbrick WM, Lee CG, Elias JA, Kim JK (2009) Interleukin-10 prevents diet-induced insulin resistance by attenuating macrophage and cytokine response in skeletal muscle. Diabetes 58:2525-2535
8. Ide A, Kawasaki E, Abiru N, Sun F, Takahashi R, Kuwahara H, Fujita N, Kita A, Oshima K, Sakamaki H, Uotani S, Yamasaki H, Yamaguchi Y, Eguchi K (2002) Genetic association between interleukin-10 gene promoter region polymorphisms and type 1 diabetes age-at-onset. Hum Immunol 63:690-695
9. Kung WJ, Lin CC, Liu SH, Chaung HC (2010) Association of interleukin-10 polymorphism with cytokines in type 2 diabetes nephropathy. Diabetes Technol Ther 12:809-813
10. Lu MY, Lakkakula BVKS, Liao YC, Tsai PC, Yang YH, Juo SHH (2011) Lack of association between the IL-10 gene polymorphisms and features of the metabolic syndrome. J Invest Med 59:27-267
11. Malecka-Tendera E, Erhardt E, Molnar D (2005) Type 2 diabetes mellitus in European children and adolescents. Acta Paediatr 94:534-546
12. Miller SA, Dykes DD, Polesky HF (1988) A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16:1215
13. Mohan V, Sandeep S, Deepa R, Shah B, Varghese C (2007) Epidemiology of type 2 diabetes: Indian scenario. Indian J Med Res 125:217-230
14. Mohebbatikaljahi H, Menevse S, Yetkin I, Demirci H (2009) Study of interleukin-10 promoter region polymorphisms (-1082A/G, -819T/C and -592A/C) in type 1 diabetes mellitus in Turkish population. J Genet 88:245-248
15. Moritani M, Yoshimoto K, Tashiro F, Hashimoto C, Miyazaki J, Ii S, Kudo E, Iwahana H, Hayashi Y, Sano T, Itakura M (1994) Transgenic expression of IL-10 in pancreatic islet A cells accelerates autoimmune insulitis and diabetes in non-obese diabetic mice. Int Immunol 6:1927-1936
16. Mosmann TR (1994) Properties and functions of interleukin-10. Adv Immunol 56:1-26
17. Opal SM, DePalo VA (2000) Anti-inflammatory cytokines. Chest 117:1162-1172
18. Pakala SV, Kurrer MO, Katz JD (1997) T helper 2 (Th2) cells induce acute pancreatitis and diabetes in immune-compromised non-obese diabetic (NOD) mice. J Exp Med 186:299-306
19. Pennline KJ, Roque-Gaffney E, Monahan M (1994) Recombinant human IL-10 prevents the onset of diabetes in the non-obese diabetic mouse. Clin Immunol Immunopathol 71:169-175
20. Saxena M, Banerjee M (2008) Diabetes: history, prevalence, insulin action and associated genes. J Appl Biosci 34:139-151
21. Scarpelli D, Cardellini M, Andreozzi F, Laratta E, Hribal ML, Marini MA, Tassi V, Lauro R, Perticone F, Sesti G (2006) Variants of the interleukin-10 promoter gene are associated with obesity and insulin resistance but not type 2 diabetes in Caucasian Italian subjects. Diabetes 55:1529-1533
22. Slobedman B, Barry PA, Spencer JV, Avdic S, Abendroth A (2009) Virus-encoded homologs of cellular interleukin-10 and their control of host immune function. J Virol 83:9618-9629
23. Tan KCB, Chow WS, Tam S, Bucala R, Betteridge J (2004) Association between acute-hase reactants and advanced glycation end products in type 2 diabetes. Diabetes Care 27:223-228
24. Tfayli H, Arslanian S (2009) Pathophysiology of type 2 diabetes mellitus in youth: the evolving chameleon. Arq Bras Endocrinol Metab 53:165-174
25. Turner DM, Williams DM, Sankaran D, Lazarus M, Sinnott PJ, Hutchinson IV (1997) An investigation of polymorphism in the interleukin-10 gene promoter. Eur J Immunogenet 24:1-8
26. van Exel E, Gussekloo J, de Craen ALM, Bootsma-van der Wiel A, Frölich M, Westendorp GJ (2002) Inflammation and stroke: the Leiden 85-lus study. Stroke 33:1135-1338