Evidence for cholesterol hyperabsorbers and hyperproducers based on comparative low-density lipoprotein reductions achieved by ezetimibe versus statins
ATORVASTATIN;
EZETIMIBE;
HIGH DENSITY LIPOPROTEIN;
HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR;
LOW DENSITY LIPOPROTEIN;
PRAVASTATIN;
ROSUVASTATIN;
SIMVASTATIN;
ACUTE CORONARY SYNDROME;
ADD ON THERAPY;
ADULT;
ARTICLE;
BODY MASS;
CHOLESTEROL BLOOD LEVEL;
COMPARATIVE STUDY;
CORONARY ARTERY BYPASS GRAFT;
CORONARY ARTERY DISEASE;
DIABETIC PATIENT;
DRUG DOSE TITRATION;
DRUG MEGADOSE;
FAMILY HISTORY;
FEMALE;
HEART REHABILITATION;
HUMAN;
MAJOR CLINICAL STUDY;
MALE;
MONOTHERAPY;
PRIORITY JOURNAL;
PROSPECTIVE STUDY;
TRANSLUMINAL CORONARY ANGIOPLASTY;
Assessment of modes of action and efficacy of plasma cholesterol-lowering drugs: Measurement of cholesterol absorption, cholesterol synthesis and bile acid synthesis and turnover using novel stable isotope techniques
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Physiological and therapeutic factors affecting cholesterol metabolism: Does a reciprocal relationship between cholesterol absorption and synthesis really exist?
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Initial low-density lipoprotein response to statin therapy predicts subsequent low-density lipoprotein response to the addition of ezetimibe
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Rationale and design of IMPROVE-IT (IM proved reduction of outcomes: Vytorin efficacy international trial): Comparison of ezetimibe/ simvastatin versus simvastatin monotherapy on cardiovascular outcomes in patients with acute coronary syndromes
Cannon CP, Giugliano RP, Blazing MA, et al. Rationale and design of IMPROVE-IT (IMProved Reduction of Outcomes: Vytorin Efficacy International Trial): comparison of ezetimibe/ simvastatin versus simvastatin monotherapy on cardiovascular outcomes in patients with acute coronary syndromes. Am Heart J. 2008;156:826-832.
Implications of recent clinical trials for the national cholesterol education program adult treatment panel III guidelines
Grundy SM, Cleeman JI, Merz CN, et al. Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines. Circulation. 2004;110:227-239.