Cell-permeable gomesin peptide promotes cell death by intracellular Ca 2+ overload

Molecular Pharmaceutics

Volumn 9, Issue 9, 2012, Pages 2686-2697

  Paredes Gamero, Edgar J ^a   Casaes Rodrigues, Rafael L ^a   Moura, Gioconda E D D ^a   Domingues, Tatiana M ^a   Buri, Marcus V ^a   Ferreira, Victor H C ^b   Trindade, Edvaldo S ^b   Moreno Ortega, Ana J ^c   Cano Abad, María F ^c   Nader, Helena B ^a   Ferreira, Alice T ^a   Miranda, Antonio ^a   Justo, Giselle Z ^a   Tersariol, Ivarne L S ^a,d  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^c INSTITUTO TEÓFILO HERNANDO   (Spain)

^d UNIVERSIDADE DE MOGI DAS CRUZES   (Brazil)

Author keywords

antimicrobial peptide; calcium; endoplasmic reticulum; gomesin; membrane permeabilization; mitochondria

Indexed keywords

CALCIUM ION; GOMESIN; POLYPEPTIDE ANTIBIOTIC AGENT; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM SIGNALING; CELL DEATH; CELL MEMBRANE PERMEABILITY; CELL ORGANELLE; CELL PERMEABILIZATION; CHO CELL; CONTROLLED STUDY; CYTOPLASM; CYTOSOL; CYTOTOXICITY; ENDOPLASMIC RETICULUM; EXTRACELLULAR MATRIX; FEMALE; GENETIC TRANSFECTION; MITOCHONDRIAL MEMBRANE POTENTIAL; MOLECULAR DYNAMICS; NONHUMAN; OSCILLATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BINDING;

ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; CALCIUM; CELL DEATH; CELL LINE; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CHO CELLS; CRICETINAE; CYTOPLASM; ENDOPLASMIC RETICULUM; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84865959221     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp300251j     Document Type: Article

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