Profibrogenic chemokines and viral evolution predict rapid progression of hepatitis C to cirrhosis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 36, 2012, Pages 14562-14567

  Farci, Patrizia ^a   Wollenberg, Kurt ^a   Diaz, Giacomo ^b   Engle, Ronald E ^a   Lai, Maria Eliana ^b   Klenerman, Paul ^c   Purcell, Robert H ^a   Pybus, Oliver G ^d   Alter, Harvey J ^e  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b UNIVERSITY OF CAGLIARI   (Italy)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Hepatitis C virus; Liver fibrosis; Rapid progressors; Slow progressors

Indexed keywords

ALANINE AMINOTRANSFERASE; CHEMOKINE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; VIRUS RNA;

ADAPTIVE IMMUNITY; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; CLINICAL ARTICLE; DISEASE COURSE; DISEASE SEVERITY; HEPATITIS C; HUMAN; LIVER CIRRHOSIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEROCONVERSION;

ALANINE TRANSAMINASE; BASE SEQUENCE; CHEMOKINE CCL4; CHEMOKINES; CLONING, MOLECULAR; DISEASE PROGRESSION; EVOLUTION, MOLECULAR; HEPACIVIRUS; HEPATITIS C; INTERFERON-GAMMA; LIVER CIRRHOSIS; MOLECULAR SEQUENCE DATA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, VIRAL; SEQUENCE ANALYSIS, DNA; STATISTICS, NONPARAMETRIC;

HEPATITIS C VIRUS;

EID: 84865955571     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1210592109     Document Type: Article

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