Improved method for the solid-phase synthesis of oligoribonucleotide 5′-triphosphates

Chemical and Pharmaceutical Bulletin

Volumn 60, Issue 9, 2012, Pages 1212-1215

  Nagat, Seigo ^a   Takagaki, Kazuchika ^a   Wada, Takeshi ^b  

^a NIPPON SHINYAKU CO LTD   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

5 triphosphate; Oligoribonucleotide; RNA; Solid phase; Triphosphorylation

Indexed keywords

OLIGOMER; OLIGORIBONUCLEOTIDE; RNA 5' TRIPHOSPHATE; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; CHEMICAL STRUCTURE; CONCENTRATION (PARAMETERS); HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NUCLEOPHILICITY; OXIDATION; PHOSPHORYLATION; REPRODUCIBILITY; RNA SYNTHESIS; SOLID PHASE SYNTHESIS; SUBSTITUTION REACTION;

OLIGORIBONUCLEOTIDES; ORGANOPHOSPHORUS COMPOUNDS; PHOSPHORYLATION; POLYPHOSPHATES; SOLID-PHASE SYNTHESIS TECHNIQUES;

EID: 84865955524     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.c12-00363     Document Type: Article

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