Synthesis and bioactivity of a novel series of 3,6-disubstituted 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles

Chinese Chemical Letters

Volumn 21, Issue 3, 2010, Pages 293-296

  Li, Ying Jun ^a   Liu, Li Jun ^a   Jin, Kun ^b   Xu, Yong Ting ^a   Sun, Su Qin ^a  

^a LIAONING NORMAL UNIVERSITY   (China)

^b DALIAN UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

Bioactivity; Synthesis; Triazolo thiadiazoles

Indexed keywords

EID: 84865861881     PISSN: 10018417     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cclet.2009.11.008     Document Type: Article

References (18)

1. M. Amir, H. Kumar, S.A. Javed, Eur. J. Med. Chem. 43 (2008) 2056.
2. S.S.P. Garoufalias, E. Tani, O. Todoulou, et al. J. Pharm. Pharmacol. 50 (1998) 117.
3. X.P. Hui, C.H. Zang, Q. Wang, et al. Indian J. Chem. 41B (2002) 2176.
4. B. Berk, E. Aktay, E. Yesilada, et al. Pharmazie 56 (2001) 613.
5. B.S. Holla, K.N. Poojary, B.S. Rao, et al. Eur. J. Med. Chem. 37 (2002) 511.
6. S.N. Swamy, B.S. Basappa, Priya, et al. Eur. J. Med. Chem. 41 (2006) 531.
7. N. Tiwari, B. Chaturvedi, Nizamuddin, Agric. Biol. Chem. 52 (1988) 1229.
8. A.R. Prasad, T. Ramlingam, A. Bhaskar Rao, et al. Indian J. Chem. 25B (1986) 566.
9. V. Srivastava, S. Sen, R. Shekar, Indian J. Chem. 33B (1994) 344.
10. M. Imtiaz Hussain, V. Kumar, Indian J. Chem. 31B (1992) 673.
11. Z.Y. Zhang, X.W. Sun, C.H. Chu, et al. J. Chin. Chem. Soc. 44 (1997) 535.
12. W.A. Denny, G.W. Rewcastle, B.C. Baguley, J. Med. Chem. 33 (1990) 814.
13. T. Fonseca, B. Gigante, T.L. Gilchrist, Tetrahedron 57 (2001) 1793.
14. H.M. Elokdah, S.Y. Chai, T.L. Sulkowski, U.S. Pat. 5,763,473 (1998).
15. S. Iyenger, M.A. Nuhlhauser, K.B. Thor, U.S. Pat.13,129 (1996).;
16. S. Iyenger, M.A. Nuhlhauser, K.B. Thor, International PCT Pat. 33,873 (1997).
17. C. Stevenson, R. Davies, H. Jeremy, Chem. Res. Toxicol. 12 (1999) 38.
18. 2S: C 59.70, H 3.81, N 16.71; Found: C 59.96, H 4.03, N 16.44. 7g. yield: 55.5%; m.p. 227.8-229.6°C