Short-term prednisolone therapy has minimal impact on calcium metabolism in dogs with atopic dermatitis

Veterinary Journal

Volumn 193, Issue 2, 2012, Pages 439-442

  Kovalik, M ^a   Thoday, K L ^a   Evans, H ^b   Berry, J ^c   van den Broek, A H M ^a   Mellanby, R J ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b Cambridge Specialist Laboratory Services   (United Kingdom)

^c MANCHESTER ROYAL INFIRMARY   (United Kingdom)

Author keywords

1,25 Dihydroxyvitamin D3; Calcium; Dog; Glucocorticoids; Parathyroid hormone

Indexed keywords

CALCITRIOL; CALCIUM; CALCIUM ION; PARATHYROID HORMONE; PHOSPHATE; PREDNISOLONE;

ADVERSE OUTCOME; ANIMAL TISSUE; ARTICLE; ATOPIC DERMATITIS; BULIMIA; CALCIUM BLOOD LEVEL; CALCIUM METABOLISM; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; DOG; DRUG DOSE TITRATION; DRUG EFFECT; FEMALE; MALE; NONHUMAN; OUTCOME ASSESSMENT; PARATHYROID HORMONE BLOOD LEVEL; PHOSPHATE BLOOD LEVEL; POLYDIPSIA; POLYURIA; PRURITUS; SCORING SYSTEM; SHORT COURSE THERAPY; URINARY EXCRETION; VITAMIN METABOLISM;

ANIMALS; BLOOD CHEMICAL ANALYSIS; CALCIUM PHOSPHATES; DERMATITIS, ATOPIC; DOG DISEASES; DOGS; DRUG ADMINISTRATION SCHEDULE; FEMALE; GLUCOCORTICOIDS; MALE; PREDNISOLONE; SCOTLAND; SERUM ALBUMIN; TIME FACTORS; VITAMIN D;

CANIS FAMILIARIS;

EID: 84865861739     PISSN: 10900233     EISSN: 15322971     Source Type: Journal    
DOI: 10.1016/j.tvjl.2011.12.003     Document Type: Article

References (42)

1. Berry, J.L., Martin, J., Mawer, E.B., 2000. 25-Hydroxyvitamin D assay kits: Speed at the cost of accuracy? In: Norman, A.W., Bouillion, R., Thomasset, M. (Eds.), Vitamin D Endocrine System: Structural, Biological, Genetic and Clinical Aspects. University of California, Riverside, CA, USA, pp. 797-800.
2. Bischoff-Ferrari H.A., Dawson-Hughes B., Willett W.C., Staehelin H.B., Bazemore M.G., Zee R.Y., Wong J.B. Effect of vitamin D on falls: A meta-analysis. Journal of the American Medical Association 2004, 291:1999-2006.
3. Colombo S., Hill P.B., Shaw D.J., Thoday K.L. Effectiveness of low dose immunotherapy in the treatment of canine atopic dermatitis: A prospective, double-blinded, clinical study. Veterinary Dermatology 2005, 16:162-170.
4. De Vries F., Bracke M., Leufkens H.G., Lammers J.W., Cooper C., Van Staa T.P. Fracture risk with intermittent high-dose oral glucocorticoid therapy. Arthritis and Rheumatism 2007, 56:208-214.
5. DeBoer D.J., Hillier A. The ACVD task force on canine atopic dermatitis (XV): Fundamental concepts in clinical diagnosis. Veterinary Immunology and Immunopathology 2001, 81:271-276.
6. Ekenstam E., Stalenheim G., Hallgren R. The acute effect of high-dose corticosteroid treatment on serum osteocalcin. Metabolism-Clinical and Experimental 1988, 37:141-144.
7. Cohn, L.A., 2010. Glucocorticoid therapy. In: Ettinger, J.S., Feldman, E.C. (Eds.), Textbook of Veterinary Internal Medicine, Seventh Ed. Saunders Elsevier, St. Louis, MO, USA, pp. 602-608.
8. Fucik R.F., Kukreja S.C., Hargis G.K., Bowser E.N., Henderson W.J.M., Williams G.A. Effect of glucocorticoids on function of parathyroid glands in man. Journal of Clinical Endocrinology and Metabolism 1975, 40:152-155.
9. Garrett E.R., Johnston R.L., Collins E.J. Quantification of normal and adrenal steroid affected calcium metabolism in the young dog. Journal of Pharmacology and Experimental Therapeutics 1964, 145:357-366.
10. Gennari C., Imbimbo B., Montagnani M., Bernini M., Nardi P., Avioli L.V. Effects of prednisone and deflazacort on mineral metabolism and parathyroid hormone activity in humans. Calcified Tissue International 1984, 36:245-252.
11. Geyer N., Bartges J.W., Kirk C.A., Cox S., Hezel A., Moyers T., Hayes J. Influence of prednisolone on urinary calcium oxalate and struvite relative supersaturation in healthy young adult female domestic shorthaired cats. Veterinary Therapeutics: Research in Applied Veterinary Medicine 2007, 8:239-246.
12. Gourlay M., Franceschini N., Sheyn Y. Prevention and treatment strategies for glucocorticoid-induced osteoporotic fractures. Clinical Rheumatology 2007, 26:144-153.
13. Gow A.G., Gow D.J., Bell R., Simpson J.W., Chandler M.L., Evans H., Berry J.L., Herrtage M.E., Mellanby R.J. Calcium metabolism in eight dogs with hypoadrenocorticism. Journal of Small Animal Practice 2009, 50:426-430.
14. Hahn, T.J., Baran, D.T., Halstead, L.R., 1979. Alterations in mineral and vitamin D metabolism produced by subacute prednisone administration in man. In: Proceedings of the 61st Annual Meeting of the Endocrine Society Abstract, pp. 195.
15. Hahn T.J., Halstead L.R., Baran D.T. Effects of short-term glucocorticoid administration on intestinal calcium absorption and circulating vitamin D metabolite concentrations in man. Journal of Clinical Endocrinology and Metabolism 1981, 52:111-115.
16. Halliwell R. Revised nomenclature for veterinary allergy. Veterinary Immunology and Immunopathology 2006, 114:207-208.
17. Hattersley A.T., Meeran K., Burrin J., Hill P., Shiner R., Ibbertson H.K. The effect of long- and short-term corticosteroids on plasma calcitonin and parathyroid hormone levels. Calcified Tissue International 1994, 54:198-202.
18. Kovalik M., Thoday K.L., Berry J., van den Broek A.H., Mellanby R.J. Prednisolone therapy for atopic dermatitis is less effective in dogs with lower pretreatment serum 25-hydroxyvitamin D concentrations. Veterinary Dermatology 2011, 10.1111/j.1365-3164.2011.01022.x.
19. Lips P. Vitamin D deficiency and secondary hyperparathyroidism in the elderly: Consequences for bone loss and fractures and therapeutic implications. Endocrine Reviews 2001, 22:477-501.
20. Mawer E.B., Berry J.L., Cundall J.P., Still P.E., White A. A sensitive radioimmunoassay using a monoclonal antibody that is equipotent for ergocalcitriol and calcitriol (1,25-dihydroxy vitamin D2 and D3). Clinica Chimica Acta 1990, 190:199-209.
21. Mawer E.B., Hann J.T., Berry J.L., Davies M. Vitamin D metabolism in patients intoxicated with ergocalciferol. Clinical Science (London) 1985, 68:135-141.
22. Mazziotti G., Angeli A., Bilezikian J.P., Canalis E., Giustina A. Glucocorticoid-induced osteoporosis: An update. Trends in Endocrinology Metabolism 2006, 17:144-149.
23. McLaughlin F., Mackintosh J., Hayes B.P., McLaren A., Uings I.J., Salmon P., Humphreys J., Meldrum E., Farrow S.N. Glucocorticoid-induced osteopenia in the mouse as assessed by histomorphometry, microcomputed tomography, and biochemical markers. Bone 2002, 30:924-930.
24. Olivry T., DeBoer D.J., Favrot C., Jackson H.A., Mueller R.S., Nuttall T., Prelaud P. Treatment of canine atopic dermatitis: 2010 Clinical Practice Guidelines from the International Task Force on Canine Atopic Dermatitis. Veterinary Dermatology 2010, 21:233-248.
25. Olivry T., Foster A.P., Mueller R.S., McEwan N.A., Chesney C., Williams H.C. Interventions for atopic dermatitis in dogs: A systematic review of randomized controlled trials. Veterinary Dermatology 2010, 21:4-22.
26. Olivry T., Marsella R., Iwasaki T., Mueller R. Validation of CADESI-03, a severity scale for clinical trials enrolling dogs with atopic dermatitis. Veterinary Dermatology 2007, 18:78-86.
27. Olivry T., Sousa C.A. The ACVD task force on canine atopic dermatitis (XX): Glucocorticoid pharmacotherapy. Veterinary Immunology and Immunopathology 2001, 81:317-322.
28. Pasco J.A., Henry M.J., Kotowicz M.A., Sanders K.M., Seeman E., Pasco J.R., Schneider H.G., Nicholson G.C. Seasonal periodicity of serum vitamin D and parathyroid hormone, bone resorption, and fractures: The Geelong Osteoporosis Study. Journal of Bone and Mineral Research 2004, 19:752-758.
29. Paz-Pacheco E., Fuleihan G.E., LeBoff M.S. Intact parathyroid hormone levels are not elevated in glucocorticoid-treated subjects. Journal of Bone and Mineral Research 1995, 10:1713-1718.
30. Peterson M.E., Kintzer P.P., Kass P.H. Pretreatment clinical and laboratory findings in dogs with hypoadrenocorticism: 225 Cases (1979-1993). Journal of the American Veterinary Medical Association 1996, 208:85-91.
31. Prummel A.M., Wiersinga W.M., Lips P., Sanders G.T.B., Sauerwein H.P. The course of biochemical parameters of bone turnover during treatment with corticosteroids. Journal of Clinical Endocrinology and Metabolism 1991, 72:382-386.
32. Quarles L.D. Prednisone-induced osteopenia in Beagles: Variable effects mediated by differential suppression of bone formation. American Journal of Physiology 1992, 263:E136-141.
33. Ramsey I.K., Tebb A., Harris E., Evans H., Herrtage M.E. Hyperparathyroidism in dogs with hyperadrenocorticism. Journal of Small Animal Practice 2005, 46:531-536.
34. Reid I.R., Evans M.C., Stapleton J. Lateral spine densitometry is a more sensitive indicator of glucocorticoid-induced bone loss. Journal of Bone and Mineral Research 1992, 7:1221-1225.
35. Rubin M.R., Bilezikian J.P. Clinical review 151: The role of parathyroid hormone in the pathogenesis of glucocorticoid-induced osteoporosis: A re-examination of the evidence. Journal of Clinical Endocrinology and Metabolism 2002, 87:4033-4041.
36. Sambrook P.N., Chen J.S., March L.M., Cameron I.D., Cumming R.G., Lord S.R., Zochling J., Sitoh Y.Y., Lau T.C., Schwarz J., Seibel M.J. Serum parathyroid hormone predicts time to fall independent of vitamin D status in a frail elderly population. Journal of Clinical Endocrinology and Metabolism 2004, 89:1572-1576.
37. Scott, D.W., Miller, W.H., Griffin, C.E., 2001. Skin immune system and allergic skin diseases. In: Muller and Kirk's Small Animal Dermatology, Sixth Ed. W.B. Saunders, Philadelphia, pp. 543-666.
38. Seeman E., Kumar R., Hunder G.G., Heath H., Riggs B.L. Production, degradation, and circulating levels of 1,25-dihydroxyvitamin D in chronic glucocorticoid excess. Calcified Tissue International 1980, 31. 83-83.
39. Silverberg S.J., Shane E., de la Cruz L., Dempster D.W., Feldman F., Seldin D., Jacobs T.P., Siris E.S., Cafferty M., Parisien M.V., et al. Skeletal disease in primary hyperparathyroidism. Journal of Bone and Mineral Research 1989, 4:283-291.
40. Weinstein R.S. Glucocorticoid-induced osteoporosis. Reviews in Endocrine and Metabolic Disorders 2001, 2:65-73.
41. Weinstein R.S. Glucocorticoids, osteocytes, and skeletal fragility: The role of bone vascularity. Bone 2010, 46:564-570.
42. Yonemura K., Hishida A., Kimura M., Watanabe T., Kumagai H. Prednisolone induces an increase in serum calcium concentration: possible involvement of the kidney, the bone, and the intestine. Calcified Tissue International 1999, 65(4):267-271.