Platelet dysfunction associated with ponatinib, a new pan BCR-ABL inhibitor with efficacy for chronic myeloid leukemia resistant to multiple tyrosine kinase inhibitor therapy

Haematologica

Volumn 97, Issue 9, 2012, Pages 1444-

  Neelakantan, Pratap ^a   Marin, David ^a   Laffan, Mike ^a   Goldman, John ^a   Apperley, Jane ^a   Milojkovic, Dragana ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

BCR ABL; Chronic myeloid leukemia; Panatinib; Platelet function; Tyrosine kinase inhibitor

Indexed keywords

ADENOSINE DIPHOSPHATE; ADRENALIN; BCR ABL PROTEIN; BOSUTINIB; COLLAGEN; DASATINIB; IMATINIB; NILOTINIB; PONATINIB; IMIDAZOLE DERIVATIVE; PROTEIN KINASE INHIBITOR; PYRIDAZINE DERIVATIVE;

BLEEDING; BLOOD CLOTTING DISORDER; BLOOD CLOTTING PARAMETERS; CHRONIC MYELOID LEUKEMIA; HUMAN; LETTER; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOCYTE COUNT; THROMBOCYTE DYSFUNCTION; THROMBOCYTOPENIA; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; DRUG RESISTANCE; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; PATHOLOGY; PROGNOSIS; THROMBOCYTE;

BLOOD PLATELETS; DRUG RESISTANCE, NEOPLASM; FUSION PROTEINS, BCR-ABL; HUMANS; IMIDAZOLES; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; PROGNOSIS; PROTEIN KINASE INHIBITORS; PYRIDAZINES;

EID: 84865852312     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2012.064618     Document Type: Letter

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