Molecular characterization of identical, novel MLL-EPS15 translocation and individual genomic copy number alterations in monozygotic infant twins with acute lymphoblastic leukemia

Haematologica

Volumn 97, Issue 9, 2012, Pages 1445-1447

  Kotecha, Rishi S ^a,b,c   Ford, Jette ^b   Beesley, Alex H ^b   Anderson, Denise ^b   Cole, Catherine H ^a,c   Kees, Ursula R ^b  

^a PRINCESS MARGARET HOSPITAL FOR CHILDREN   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Beta thalassemia; Globin promoter; Hemoglobin A2; Indian; Mutation

Indexed keywords

CD19 ANTIGEN; CD24 ANTIGEN; COMMON ACUTE LYMPHOBLASTIC LEUKEMIA ANTIGEN; EPIDERMAL GROWTH FACTOR RECEPTOR PATHWAY SUBSTRATE 15; MIXED LINEAGE LEUKEMIA PROTEIN; EPS15 PROTEIN, HUMAN; MLL PROTEIN, HUMAN; ONCOPROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ACUTE LYMPHOBLASTIC LEUKEMIA; CHROMOSOME 11Q; CHROMOSOME ANALYSIS; CHROMOSOME BREAKAGE; CHROMOSOME TRANSLOCATION; COPY NUMBER VARIATION; DNA END JOINING REPAIR; EXON; FLUORESCENCE IN SITU HYBRIDIZATION; FUSION GENE; GENE EXPRESSION PROFILING; GENE REARRANGEMENT; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; IMMUNOPHENOTYPING; INFANT; KARYOTYPE; LETTER; MONOZYGOTIC TWINS; PRE B LYMPHOCYTE; SEQUENCE ANALYSIS; CHROMOSOME 11; CHROMOSOME 4; GENE TRANSLOCATION; GENETICS; PROGNOSIS; TWINS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CHROMOSOMES, HUMAN, PAIR 11; CHROMOSOMES, HUMAN, PAIR 4; DNA COPY NUMBER VARIATIONS; GENE REARRANGEMENT; HUMANS; INFANT; MYELOID-LYMPHOID LEUKEMIA PROTEIN; ONCOGENE PROTEINS, FUSION; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROGNOSIS; TRANSLOCATION, GENETIC; TWINS, MONOZYGOTIC;

EID: 84865844550     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2012.062299     Document Type: Letter

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