The efficacy and safety of a high dose of vitamin d in mothers with gestational diabetes mellitus: A randomized controlled clinical trial

Iranian Journal of Medical Sciences

Volumn 37, Issue 3, 2012, Pages 159-165

  Hosseinzadeh Shamsi Anar, Mahdieh ^a   Mozaffari Khosravi, Hassan ^a   Salami, Maryam Alsadat ^a   Hadinedoushan, Hossein ^a   Mozayan, Mohammad Reza ^a  

^a SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Cholecalciferol; Gestational diabetes mellitus; Vitamin D

Indexed keywords

CALCIUM; HEMOGLOBIN A1C; PARATHYROID HORMONE; PHOSPHORUS; VITAMIN D;

ADULT; ARTICLE; CALCIUM BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG EFFICACY; DRUG MEGADOSE; DRUG RESPONSE; DRUG SAFETY; FEMALE; FOLLOW UP; HEMOGLOBIN BLOOD LEVEL; HUMAN; OUTCOME ASSESSMENT; PARATHYROID HORMONE BLOOD LEVEL; PHOSPHATE BLOOD LEVEL; PREGNANCY DIABETES MELLITUS; RANDOMIZED CONTROLLED TRIAL; SINGLE DRUG DOSE; VITAMIN BLOOD LEVEL; VITAMIN D DEFICIENCY;

EID: 84865809568     PISSN: 02530716     EISSN: 17353688     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Zhang C, Qiu C, Hu FB, David RM, van Dam RM, Bralley A, et al. Maternal plasma 25-hydroxyvitamin D concentrations and the risk for gestational diabetes mellitus. PLoS One. 2008;3:e3753. doi: 10.1371/journal.pone.0003753. PubMed PMID: 19015731;PubMed Central PMCID: PMC2582131.
2. Dawodu A, Wagner CL. Mother-child vitamin D deficiency: an international perspective. Arch Dis Child. 2007;92:737-740. doi: 10.1136/adc.2007.122689. PubMed PMID: 17715433;PubMed Central PMCID: PMC2084036.
3. Sachan A, Gupta R, Das V, Agarwal A, Awasthi PK, Bhatia V. High prevalence of vitamin D deficiency among pregnant women and their newborns in northern India. Am J Clin Nutr. 2005;81:1060-1064. PubMed PMID: 15883429.
4. Bassir M, Laborie S, Lapillonne A, Claris O, Chappuis MC, Salle BL. Vitamin D deficiency in Iranian mothers and their neonates: a pilot study. Acta Paediatr. 2001;90:577-579. doi:10.1080/08035250119986. PubMed PMID:11430721.
5. Gannagé-Yared MH, Chemali R, Yaacoub N, Halaby G. Hypovitaminosis D in a sunny country: relation to lifestyle and bone markers. J Bone Miner Res. 2000;15:1856-1862. doi:10.1359/jbmr.2000.15.9.1856. PubMed PMID:10977006.
6. Hollis BW, Wagner CL. Vitamin D requirements during lactation: high-dose maternal supplementation as therapy to prevent hypovitaminosis D for both the mother and the nursing infant. Am J Clin Nutr. 2004;80:1752S-1758S. PubMed PMID: 15585800.
7. Chiu KC, Chuang LM, Yoon C. The vitamin D receptor polymorphism in the translation initiation codon is a risk factor for insulin resistance in glucose tolerant Caucasians. BMC Med Genet. 2001;2:2. PubMed PMID: 1123188; PubMed Central PMCID:PMC29095.
8. Mattila C, Knekt P, Männistö S, Rissanen H, Laaksonen MA, Montonen J, et al. Serum 25-hydroxyvitamin D concentration and subsequent risk of type 2 diabetes. Diabetes Care. 2007;30:2569-2570. doi: 10.2337/dc07-0292. PubMed PMID: 17626891.
9. Norman AW, Frankel JB, Heldt AM, Grodsky GM. Vitamin D deficiency inhibits pancreatic secretion of insulin. Science. 1980;209:823-825. doi: 10.1126/science.6250216. PubMedPMID: 6250216.
10. Palomer X, González-Clemente JM, Blanco-Vaca F, Mauricio D. Role of vitamin D in the pathogenesis of type 2 diabetes mellitus. Diabetes Obes Metab. 2008;10:185-197. doi:10.1111/j.1463-1326.2007.00710.x. PubMedPMID: 18269634.
11. Chiu KC, Chu A, Go VL, Saad MF. Hypovitaminosis D is associated with insulin resistance and beta cell dysfunction. Am J Clin Nutr. 2004;79:820-825. PubMed PMID:15113720.
12. Maghbooli Z, Hossein-Nezhad A, Karimi F, Shafaei AR, Larijani B. Correlation between vitamin D3 deficiency and insulin resistance in pregnancy. Diabetes Metab Res Rev. 2008;24:27-32. doi: 10.1002/dmrr.737.PubMed PMID: 17607661.
13. Hashemipour S, Larijani B, Adibi H, Javadi E, Sedaghat M, Pajouhi M, et al. Vitamin D deficiency and causative factors in the population of Tehran. BMC Public Health. 2004;4:38. PubMed PMID: 15327695; PubMed Central PMCID: PMC517720.
14. Wagner CL, Taylor SN, Hollis BW. Does vitamin D make the world go 'round'?. Breastfeed Med. 2008;3:239-250. doi: 10.1089/bfm.2008.9984. PubMed PMID: 19086827; PubMed Central PMCID: PMC2981372.
15. Diamond TH, Ho KW, Rohl PG, Meerkin M. Annual intramuscular injection of a megadose of cholecalciferol for treatment of vitamin D deficiency: efficacy and safety data. Med J Aust. 2005;183:10-12. PubMed PMID:15992330.
16. Ebeling PR. Megadose therapy for vitamin D deficiency. Med J Aust. 2005;183:4-5. PubMed PMID: 15992326.
17. Einarsdóttir K, Preen DB, Clay TD, Kiely L, Holman CD, Cohen LD. Effect of a single 'megadose' intramuscular vitamin D (600,000 IU) injection on vitamin D concentrations and bone mineral density following biliopancreatic diversion surgery. Obes Surg. 2010;20:732-737. doi: 10.1007/s11695-009-0024-3. PubMedPMID: 19949888.
18. Mallet E, Philippe F, Castanet M, Basuyau JP. [Administration of a single Winter oral dose of 200,000 IU of vitamin D3 in adolescents in Normandy: evaluation of the safety and vitamin D status obtained]. Arch Pediatr. 2010;17:1042-1046. PubMed PMID: 20542672.
19. Markestad T, Hesse V, Siebenhuner M, Jahreis G, Aksnes L, Plenert W, et al. Intermittent highdose vitamin D prophylaxis during infancy: effect on vitamin D metabolites, calcium, and phosphorus. Am J Clin Nutr. 1987;46:652-658. PubMed PMID: 3499065.
20. Sanders KM, Stuart AL, Williamson EJ, Simpson JA, Kotowicz MA, Young D, et al. Annual high-dose oral vitamin D and falls and fractures in older women: a randomized controlled trial. JAMA. 2010;303:1815-1822. doi: 10.1001/jama.2010.594. PubMed PMID:20460620.
21. Shakiba M, Sadr S, Nefei Z, Mozaffari-Khosravi H, Lotfi MH, Bemanian MH. Combination of bolus dose vitamin D with routine vaccination in infants: a randomised trial. Singapore Med J. 2010;51:440-445. PubMed PMID: 20593151.
22. Soliman AT, Adel A, Wagdy M, Alali M, Aziz Bedair EM. Manifestations of severe vitamin D deficiency in adolescents: effects of intramuscular injection of a megadose of cholecalciferol. J Trop Pediatr. 2011;57:303-306. doi: 10.1093/tropej/fmq028. PubMed PMID:20427425.
23. von Restorff C, Bischoff-Ferrari HA, Theiler R. High-dose oral vitamin D3 supplementation in rheumatology patients with severe vitamin D3 deficiency. Bone. 2009;45:747-749. doi:10.1016/j.bone.2009.06.012. PubMed PMID:19539796.
24. Witham MD, Dove FJ, Dryburgh M, Sugden JA, Morris AD, Struthers AD. The effect of different doses of vitamin D(3) on markers of vascular health in patients with type 2 diabetes: a randomised controlled trial. Diabetologia. 2010;53:2112-2119. PubMed PMID:20596692.
25. Ferrara A, Hedderson MM, Quesenberry CP, Selby JV. Prevalence of gestational diabetes mellitus detected by the national diabetes data group or the carpenter and coustan plasma glucose thresholds. Diabetes Care. 2002;25:1625-1630. doi: 10.2337/diacare.25.9.1625. PubMed PMID: 12196438.
26. von Restorff C, Bischoff-Ferrari HA, Theiler R. High-dose oral vitamin D3 supplementation in rheumatology patients with severe vitamin D3 deficiency. Bone. 2009;45:747-749. doi:10.1016/j.bone.2009.06.012. PubMed PMID:19539796.
27. Carpenter MW, Coustan DR. Criteria for screening tests for gestational diabetes. Am J Obstet Gynecol. 1982;144:768-773. PubMedPMID: 7148898.
28. O'Sullivan JB, Mahan CM, Charles D, Dandrow RV. Screening criteria for high-risk gestational diabetic patients. Am J Obstet Gynecol. 1973;116:895-900. PubMed PMID:4718216.