Macrophages and mast cells are involved in carotid plaque instability

Romanian Journal of Morphology and Embryology

Volumn 52, Issue 3 SUPPL., 2012, Pages 981-984

  Marzullo, A ^a   Ciccone, M M ^a   Covelli, Claudia ^a   Serio, Gabriella ^a   Ribatti, D ^a  

^a UNIVERSITY OF BARI MEDICAL SCHOOL   (Italy)

Author keywords

Angiogenesis; Carotid plaque; Inflammation; Macrophages; Mast cells

Indexed keywords

EID: 84865801371     PISSN: 12200522     EISSN: 20668279     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Spagnoli LG, Mauriello A, Palmieri G, Santeusanio G, Amante A, Taurino M, Relationships between risk factors and morphological patterns of human carotid atherosclerotic plaques. A multivariate discriminant analysis, Atherosclerosis, 1994, 108(1):39-60.
2. Carr S, Farb A, Pearce WH, Virmani R, Yao JS, Atherosclerotic plaque rupture in symptomatic carotid artery stenosis, J Vasc Surg, 1996, 23(5):755-765; discussion 765-766.
3. Fisher M, Paganini-Hill A, Martin A, Cosgrove M, Toole JF, Barnett HJ, Norris J, Carotid plaque pathology: thrombosis, ulceration, and stroke pathogenesis, Stroke, 2005, 36(2):253-257.
4. Spagnoli LG, Mauriello A, Sangiorgi G, Fratoni S, Bonanno E, Schwartz RS, Piepgras DG, Pistolese R, Ippoliti A, Holmes DR Jr, Extracranial thrombotically active carotid plaque as a risk factor for ischemic stroke, JAMA, 2004, 292(15):1845-1852.
5. Bassiouny HS, Sakaguchi Y, Mikucki SA, McKinsey JF, Piano G, Gewertz BL, Glagov S, Juxtalumenal location of plaque necrosis and neoformation in symptomatic carotid stenosis, J Vasc Surg, 1997, 26(4):585-594.
6. Jander S, Sitzer M, Schumann R, Schroeter M, Siebler M, Steinmetz H, Stoll G, Inflammation in high-grade carotid stenosis: a possible role for macrophage and T cells in plaque destabilization, Stroke, 1998, 29(8):1625-1630.
7. North American Symptomatic Carotid Endarterectomy Trial Collaborators, Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis, N Engl J Med, 1991, 325(7):445-453.
8. Mauriello A, Sangiorgi G, Palmieri G, Virmani R, Holmes DR Jr, Schwartz RS, Pistolese R, Ippoliti A, Spagnoli LG, Hyperfibrinogenemia is associated with specific histocytological composition and complications of atherosclerotic carotid plaques in patients affected by transient ischemic attacks, Circulation, 2000, 101(7):744-750.
9. van Oostrom O, Velema E, Schoneveld AH, de Vries JP, de Bruin P, Seldenrijk CA, de Kleijn DP, Busser E, Moll FL, Verheijen JH, Virmani R, Pasterkamp G, Age-related changes in plaque composition: a study in patients suffering from carotid artery stenosis, Cardiovasc Pathol, 2005, 14(3):126-134.
10. Husain T, Abbott CR, Scott DJ, Gough MJ, Macrophage accumulation within the cap of carotid atherosclerotic plaques is associated with the onset of cerebral ischemic events, J Vasc Surg, 1999, 30(2):269-276.
11. Tipping PG, Hancock WW, Production of tumor necrosis factor and interleukin-1 by macrophage from human atheromatous plaques, Am J Pathol, 1993, 142(6):1721-1728.
12. Clinton SK, Underwood R, Hayes L, Sherman ML, Kufe DW, Libby P, Macrophage colony-stimulating factor gene expression in vascular cells and in experimental and human atherosclerosis, Am J Pathol, 1992, 140(2):301-316.
13. Davies MJ, Richardson PD, Woolf N, Katz DR, Mann J, Risk of thrombosis in human atherosclerotic plaques: role of extracellular lipid, macrophage, and smooth muscle cell content, Br Heart J, 1993, 69(5):377-381.
14. Kaartinen M, Penttilä A, Kovanen PT, Accumulation of activated mast cells in the shoulder region of human coronary atheroma, the predilection site of atheromatous rupture, Circulation, 1994, 90(4):1669-1678.
15. Kaartinen M, Penttilä A, Kovanen PT, Mast cells accompany microvessels in human coronary atheromas: implications for intimal neovascularization and hemorrhage, Atherosclerosis, 1994, 123(1-2):123-131.
16. Ribatti D, Crivellato E, Immune cells and angiogenesis, J Cell Mol Med, 2009, 13(9A):2822-2833.
17. Jeziorska M, Woolley DE, Local neovascularization and cellular composition within vulnerable regions of atherosclerotic plaques of human carotid arteries, J Pathol, 1999, 188(2):189-196.
18. Ribatti D, Levi-Schaffer F, Kovanen PT, Inflammatory angiogenesis in atherogenesis a double-edged sword, Ann Med, 2008, 40(8):606-621.
19. Koutouzis M, Nomikos A, Nikolidakis S, Tzavara V, Andrikopoulos V, Nikolaou N, Barbatis C, Kyriakides ZS, Statin treated patients have reduced intraplaque angiogenesis in carotid endarterectomy specimens, Atherosclerosis, 2007, 192(2):457-463.