Association of MYH9/APOL1 with chronic kidney disease in a UK population

Nephrology Dialysis Transplantation

Volumn 27, Issue 9, 2012, Pages 3660-

  McKnight, Amy Jayne ^a   Duffy, Seamus ^a   Fogarty, Damian G ^a   Maxwell, Alexander P ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

APOL1 GENE; CHRONIC KIDNEY DISEASE; DIABETIC NEPHROPATHY; GENE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENE MUTATION; GENETIC ASSOCIATION; GENOTYPE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; KIDNEY FAILURE; LETTER; MYH9 GENE; NON INSULIN DEPENDENT DIABETES MELLITUS; PHENOTYPE; PRIORITY JOURNAL; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; UNITED KINGDOM;

DIABETES MELLITUS, TYPE 2; DIABETIC NEPHROPATHIES; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HUMANS; KIDNEY FAILURE, CHRONIC; MALE; MOLECULAR MOTOR PROTEINS; MYOSIN HEAVY CHAINS; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84865785706     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfs181     Document Type: Letter

References (5)

1. Seri M, Cusano R, Gangarossa S et al. Mutations in MYH9 result in the May-Hegglin anomaly, and Fechtner and Sebastian syndromes. The May-Heggllin/Fechtner Syndrome Consortium. Nat Genet 2000; 26: 103-105.
2. Freedman BI, Langefeld CD. The new era of APOL1-associated glomerulosclerosis. Nephrol Dial Transplant 2012; doi:10.1093/ndt/gfr812.
3. Tzur S, Rosset S, Shemer R et al. Missense mutations in the APOL1 gene are highly associated with end stage kidney disease risk previously attributed to the MYH9 gene. Hum Genet 2010; 128: 345-350.
4. Cooke JN, Bostrom MA, Hicks PJ et al. Polymorphisms in MYH9 are associated with diabetic nephropathy in European Americans. Nephrol Dial Transplant 2011; doi:10.1093/ndt/gfr522.
5. O'Seaghdha CM, Parekh RS, Hwang SJ et al. The MYH9/APOL1 region and chronic kidney disease in European-Americans. Hum Mol Genet 2011; 20: 2450-2456.