Viscerosomatic facilitation in a subset of IBS patients, an effect mediated by N-methyl-D-aspartate receptors

Journal of Pain

Volumn 13, Issue 9, 2012, Pages 901-909

  Verne, G Nicholas ^a,b   Price, Donald D ^c   Callam, Christopher S ^d   Zhang, Buyi ^d   Peck, Josh ^d   Zhou, Qiqi ^a,b  

^a University of Texas Medical Branch School of Medicine   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^d OHIO STATE UNIVERSITY   (United States)

Author keywords

dextromethorphan; Irritable bowel syndrome (IBS); NMDA receptor; repetitive afferent barrage; visceral and thermal hypersensitivity; viscerosomatic facilitation

Indexed keywords

ANALGESIC AGENT; CAFFEINE; DEXTROMETHORPHAN; DIPHENHYDRAMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PLACEBO;

ADULT; ARTICLE; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FACILITATION; FEMALE; HUMAN; HYPERALGESIA; IRRITABLE COLON; LEG; MAJOR CLINICAL STUDY; MALE; MEDIATOR; MULTICENTER STUDY; NERVE CONDUCTION; NOCICEPTION; PAIN ASSESSMENT; PAIN THRESHOLD; RANDOMIZED CONTROLLED TRIAL; RECTUM; SKIN ALLERGY; SYMPTOM; THERMAL STIMULATION; TREATMENT OUTCOME; VISCERAL PAIN; VISCEROSOMATIC FACILITATION; VISUAL ANALOG SCALE;

ADULT; ANXIETY; DEPRESSION; DEXTROMETHORPHAN; DOUBLE-BLIND METHOD; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; HOT TEMPERATURE; HUMANS; HYPERALGESIA; IRRITABLE BOWEL SYNDROME; LEG; MALE; PAIN MEASUREMENT; PAIN THRESHOLD; PHYSICAL STIMULATION; PSYCHIATRIC STATUS RATING SCALES; RECEPTORS, N-METHYL-D-ASPARTATE; RECTUM; VISCERAL PAIN; YOUNG ADULT;

EID: 84865757237     PISSN: 15265900     EISSN: 15288447     Source Type: Journal    
DOI: 10.1016/j.jpain.2012.06.002     Document Type: Article

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