Stable incidence of HIV diagnoses among Danish MSM despite increased engagement in unsafe sex

Journal of Acquired Immune Deficiency Syndromes

Volumn 61, Issue 1, 2012, Pages 106-111

  Cowan, Susan Alice ^a   Gerstoft, Jan ^b   Haff, Jakob ^c   Christiansen, Annette Hartvig ^a   Nielsen, Jens ^a   Obel, Niels ^b  

^a STATENS SERUM INSTITUT   (Denmark)

^b Mental Health Services CPH   (Denmark)

^c STOP AIDS Gay Men's HIV Organization   (Denmark)

Author keywords

HAART; HIV; MSM; syphilis; transmission rate; unsafe sex

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; VIRUS RNA;

ADULT; ANUS INTERCOURSE; ARTICLE; CD4 LYMPHOCYTE COUNT; COHORT ANALYSIS; DENMARK; DISEASE REGISTRY; HEALTH SURVEY; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HIV TEST; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFECTION RATE; MAJOR CLINICAL STUDY; MALE; MALE HOMOSEXUAL; PRIORITY JOURNAL; RISK ASSESSMENT; SEXUALLY TRANSMITTED DISEASE; SYPHILIS; UNSAFE SEX; VIRUS LOAD;

ADULT; ANTI-RETROVIRAL AGENTS; COHORT STUDIES; DENMARK; HIV; HIV INFECTIONS; HOMOSEXUALITY, MALE; HUMANS; INCIDENCE; MALE; SYPHILIS; UNSAFE SEX; VIRAL LOAD;

EID: 84865742209     PISSN: 15254135     EISSN: 10779450     Source Type: Journal    
DOI: 10.1097/QAI.0b013e31825af890     Document Type: Article

References (28)

1. Quinn TC, Wawer MJ, Sewankambo N, et al. Viral load and heterosexual transmission of human immunodeficiency virus type 1. Rakai Project Study Group. N Engl J Med. 2000;342:921-929.
2. Attia S, Egger M, Müller M, et al. Sexual transmission of HIV according to viral load and antiretroviral therapy: systematic review and metaanalysis. AIDS. 2009;23:1397-1404.
3. Donnell D, Baeten JM, Kiarie J, et al. Heterosexual HIV-1 transmission after initiation of antiretroviral therapy: a prospective cohort analysis. Lancet. 2010;375:2092-2098.
4. Granich RM, Gilks CF, Dye C, et al. Universal voluntary HIV testing with immediate antiretroviral therapy as a strategy for elimination of HIV transmission: a mathematical model. Lancet. 2009;373:48-57.
5. Cohen MS, Chen YQ, McCauley M, et al. Prevention of HIV-1 infection with early antiretroviral therapy. N Engl J Med. 2011;365:493-505.
6. Fang C-T, Hsu H-M, Twu S-J, et al. Decreased HIV transmission after a policy of providing free access to highly active antiretroviral therapy in Taiwan. J Infect Dis. 2004;190:879-885.
7. Montaner JS, Lima VD, Barrios R, et al. Association of highly active antiretroviral therapy coverage, population viral load, and yearly new HIV diagnoses in British Columbia, Canada: a population-based study. Lancet. 2010;376:532-539.
8. Das M, Chu PL, Santos G-M, et al. Decreases in community viral load are accompanied by reductions in new HIV infections in San Francisco. PLoS One. 2010;5:e11068.
9. Cowan SA, Haff J. HIV and risk behaviour among men who have sex with men in Denmark-the 2006 Sex Life Survey. Euro Surveill. 2008;13:19050. Available at: http://www.ncbi.nlm.nih. gov/pubmed/19040825. Accessed January 10, 2012.
10. Haff J, Cowan S. The 2009 Sex Life Survey. 2009. Available at: http://www.ssi.dk/Service/Sygdomsleksikon/H/;/media/839BC82408B4 4489B619AFF0382AC074.ashx. Accessed January 10, 2012.
11. Smith E. HIV/AIDS surveillance in Denmark: the challenges ahead. J Acquir Immune Defic Syndr. 2003;32(suppl 1):S33-S38.
12. Hamers F, Phillips A. Diagnosed and undiagnosed HIV-infected populations in Europe. HIV Med. 2008;9(suppl 2):6-12.
13. Lohse N, Hansen A-BE, Jensen-Fangel S, et al. Demographics of HIV-1 infection in Denmark: results from the Danish HIV Cohort Study. Scand J Infect Dis. 2005;37:338-343.
14. Cowan SA, Smith E. Incidence of HIV/AIDS in Denmark, 1990-2005 [article in Danish]. Ugeskr Laeger. 2006;168:2247-2252.
15. Dougan S, Elford J, Chadborn TR, et al. Does the recent increase in HIV diagnoses among men who have sex with men in the UK reflect a rise in HIV incidence or increased uptake of HIV testing? Sex Transm Infect. 2007;83:120-125; Discussion 125.
16. Blower SM, Gershengorn HB, Grant RM. A tale of two futures: HIV and antiretroviral therapy in San Francisco. Science. 2000;287:650-654.
17. Law MG, Prestage G, Grulich A, et al. Modelling the effect of combination antiretroviral treatments on HIV incidence. AIDS. 2001; 15:1287-1294.
18. Marks G, Crepaz N, Janssen RS. Estimating sexual transmission of HIV from persons aware and unaware that they are infected with the virus in the USA. AIDS. 2006;20:1447-1450.
19. Truong HM, Truong H-HM, Kellogg T, et al. Increases in sexually transmitted infections and sexual risk behaviour without a concurrent increase in HIV incidence among men who have sex with men in San Francisco: a suggestion of HIV serosorting? Sex Transm Infect. 2006;82:461-466.
20. Scheer S, Kellogg T, Klausner JD, et al. HIV is hyperendemic among men who have sex with men in San Francisco: 10-year trends in HIV incidence, HIV prevalence, sexually transmitted infections and sexual risk behaviour. Sex Transm Infect. 2008;84:493-498.
21. Heijman RLJ, Stolte IG, Thiesbrummel HFJ, et al. Opting out increases HIV testing in a large sexually transmitted infections outpatient clinic. Sex Transm Infect. 2009;85:249-255.
22. Le Vu S, Le Strat Y, Barin F, et al. Population-based HIV-1 incidence in France, 2003-2008: a modelling analysis. Lancet Infect Dis. 2010;10: 682-687.
23. Semaille C, Cazein F, Lot F, et al. Recently acquired HIV infection in men who have sex with men (MSM) in France, 2003-2008. Euro Surveill. 2009;14:19425. Available at: http://www.ncbi.nlm.nih.gov/pubmed/20003900. Accessed January 10, 2012.
24. Ginige S, Chen MY, Hocking JS, et al. Rising HIV notifications in Australia: accounting for the increase in people living with HIV and implications for the HIV transmission rate. Sex Health. 2007;4:31-33.
25. Prestage G, Jin F, Zablotska IB, et al. Trends in HIV testing among homosexual and bisexual men in eastern Australian states. Sex Health. 2008;5:119-123.
26. Marrone J, Fairley CK, Chen M, et al. Comparisons of trends in antiretroviral use and HIV notification rates between three Australian states. Aust N Z J Public Health. 2007;31:131-134.
27. Audelin A, Cowan S, Obel N, et al. Phylogenetics of the Danish HIV epidemic: the role of the very late presenters. Rev Antiviral Ther Infect Dis. 2012;2:6. Abstract O-04. Presented at the 10th European meeting on HIV and Hepatitis, Treatment strategies and antiviral drug resistance; March 28-30, 2012; Barcelona, Spain.
28. EPI-NEWS. 2009. New strategy for HIV testing. No 46. Available at: http://www.ssi.dk/English/News/EPI-NEWS/;/media/Indhold/EN%20-% 20engelsk/EPI-NEWS/2009/pdf/EPI-NEWS%20-%202009%20-%20No% 2046.ashx. Accessed January 10, 2012.