Liquid chromatography-tandem mass spectrometry to determine the stability of collagen pentapeptide (KTTKS) in rat skin

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 905, Issue , 2012, Pages 113-117

  Park, Eun Ji ^a   Kim, Myung Sun ^a   Choi, Yun Lim ^a   Shin, Young Hee ^a   Lee, Hye Suk ^b   Na, Dong Hee ^a,c  

^a Kyungsung University   (South Korea)

^b The Catholic University of Korea   (South Korea)

^c Kyungpook National University   (South Korea)

Author keywords

Collagen pentapeptide; LC MS MS; Skin; Stability

Indexed keywords

CALIBRATION CURVES; CHROMATOGRAPHIC CONDITIONS; CONCENTRATION RANGES; DEGRADATION RATE; EXTRACELLULAR; ION-PAIRING REAGENT; ISOCRATIC ELUTION; LC-MS/MS; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; MOBILE PHASE; MULTIPLE-REACTION MONITORING MODES; PENTAFLUOROPROPIONIC ACIDS; PEPTIDE BONDS; RAT SKIN; TRIPLE-QUADRUPOLE MASS SPECTROMETER;

ACETONITRILE; CELL CULTURE; CONVERGENCE OF NUMERICAL METHODS; DEGRADATION; DEIONIZED WATER; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; RATS; SKIN;

COLLAGEN;

ACETONITRILE; AMINOPEPTIDASE; COLLAGEN; LYSYLTHREONYLTHREONYLLYSYLSERINATE; PEPTIDE; UNCLASSIFIED DRUG; WATER;

ANIMAL TISSUE; ARTICLE; ENZYME DEGRADATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROPHOBICITY; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN STABILITY; RAT; SKIN; SKIN FIBROBLAST; TANDEM MASS SPECTROMETRY;

ANIMALS; CHROMATOGRAPHY, LIQUID; COLLAGEN; DRUG STABILITY; KINETICS; LINEAR MODELS; OLIGOPEPTIDES; RATS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SKIN; TANDEM MASS SPECTROMETRY;

RATTUS;

EID: 84865741393     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2012.08.010     Document Type: Article

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