Thermal Detection Thresholds of Aδ- and C-Fibre Afferents Activated by Brief CO2 Laser Pulses Applied onto the Human Hairy Skin

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Churyukanov, Maxim ^a,b,c   Plaghki, Léon ^a   Legrain, Valéry ^d   Mouraux, André ^a   El Deredy, Wael ^e  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b I M SECHENOV FIRST MOSCOW STATE MEDICAL UNIVERSITY   (Russian Federation)

^c INSTITUTE OF GENERAL PATHOLOGY AND PATHOPHYSIOLOGY   (Russian Federation)

^d GHENT UNIVERSITY   (Belgium)

^e UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ALGORITHM; ARTICLE; C FIBER; CARBON DIOXIDE LASER; CONTROLLED STUDY; DELTA NERVE FIBER; EVENT RELATED POTENTIAL; FEEDBACK SYSTEM; FEMALE; HEAT SENSITIVITY; HUMAN; HUMAN TISSUE; MALE; MOLECULAR DYNAMICS; PAIN THRESHOLD; RELIABILITY; RESPONSE TIME; SENSORY NERVE; SIGNAL DETECTION; SKIN SENSATION; SKIN TEMPERATURE; STIMULUS RESPONSE; TEMPERATURE MEASUREMENT; THERMAL STIMULATION; EVOKED SOMATOSENSORY RESPONSE; HEAT; LASER; MYELINATED NERVE; NOCICEPTIVE RECEPTOR; NONMYELINATED NERVE; PHYSIOLOGY; RADIATION EXPOSURE; REACTION TIME; SKIN;

ADULT; EVOKED POTENTIALS, SOMATOSENSORY; FEMALE; HOT TEMPERATURE; HUMANS; LASERS, GAS; MALE; NERVE FIBERS, MYELINATED; NERVE FIBERS, UNMYELINATED; NOCICEPTORS; PAIN THRESHOLD; REACTION TIME; SKIN; SKIN TEMPERATURE;

EID: 84865735125     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0035817     Document Type: Article

References (35)

1. Bromm B, Jahnke MT, Treede RD, (1984) Responses of human cutaneous afferents to CO2 laser stimuli causing pain. Exp Brain Res 55: 158-166.
2. Carmon A, Mor J, Goldberg J, (1976) Evoked cerebral responses to noxious thermal stimuli in humans. Exp Brain Res 25: 103-107.
3. Plaghki L, Mouraux A, (2005) EEG and laser stimulation as tools for pain research. Curr Opin Investig Drugs 6: 58-64.
4. Treede RD, (2003) Neurophysiological studies of pain pathways in peripheral and central nervous system disorders. J Neurol 250: 1152-1161.
5. Plaghki L, Mouraux A, (2003) How do we selectively activate skin nociceptors with a high power infrared laser? Physiology and biophysics of laser stimulation. Neurophysiol Clin 33: 269-277.
6. Plaghki L, Mouraux A, (2002) Brain responses to signals ascending through C-fibers. In: Hirata K, editors. International Congress Series Amsterdam Elsevier pp. 181-192.
7. Mouraux A, Guerit JM, Plaghki L, (2004) Refractoriness cannot explain why C-fiber laser-evoked brain potentials are recorded only if concomitant Adelta-fiber activation is avoided. Pain 112: 16-26.
8. Mouraux A, Plaghki L, (2007) Are laser-evoked brain potentials modulated by attending to first or second pain? Pain 129: 321-331.
9. Cruccu G, Anand P, Attal N, Garcia-Larrea L, Haanpaa M, et al.(2004) EFNS guidelines on neuropathic pain assessment. Eur J Neurol 11: 153-162.
10. Bromm B, Neitzel H, Tecklenburg A, Treede RD, (1983) Evoked cerebral potential correlates of C-fibre activity in man. Neurosci Lett 43: 109-114.
11. Nahra H, Plaghki L, (2003) The effects of A-fiber pressure block on perception and neurophysiological correlates of brief non-painful and painful CO2 laser stimuli in humans. Eur J Pain 7: 189-199.
12. Bragard D, Chen ACN, Plaghki L, (1996) Direct isolation of ultra-late (C-fibre) evoked brain potentials by CO2 laser stimulation of tiny cutaneous surface areas in man. Neurosci Lett 209: 81-84.
13. Opsommer E, Weiss T, Miltner WH, Plaghki L, (2001) Scalp topography of ultralate (C-fibres) evoked potentials following thulium YAG laser stimuli to tiny skin surface areas in humans. Clin Neurophysiol 112: 1868-1874.
14. Ochoa J, Mair WG, (1969) The normal sural nerve in man. I. Ultrastructure and numbers of fibres and cells. Acta Neuropathol (Berl) 13: 197-216.
15. Magerl W, Ali Z, Ellrich J, Meyer RA, Treede RD, (1999) C- and A delta-fiber components of heat-evoked cerebral potentials in healthy human subjects. Pain 82: 127-137.
16. Meyer RA, Walker RE, Mountcastle VB Jr, (1976) A laser stimulator for the study of cutaneous thermal and pain sensations. IEEE Trans Biomed Eng 23: 54-60.
17. Baumgartner U, Cruccu G, Iannetti GD, Treede RD, (2005) Laser guns and hot plates. Pain 116: 1-3.
18. Bromm B, Treede RD, (1984) Nerve fibre discharges, cerebral potentials and sensations induced by CO2 laser stimulation. Hum Neurobiol 3: 33-40.
19. Bjerring P, Arendt-Nielsen L, (1988) Argon laser induced single cortical responses: a new method to quantify pre-pain and pain perceptions. J Neurol Neurosurg Psychiatry 51: 43-49.
20. Mouraux A, Guerit JM, Plaghki L, (2003) Non-phase locked electroencephalogram (EEG) responses to CO2 laser skin stimulations may reflect central interactions between Aδ- and C-fibre afferent volleys. Clin Neurophysiol 114: 710-722.
21. Opsommer E, Masquelier E, Plaghki L, (1999) Determination of nerve conduction velocity of C-fibres in humans from thermal thresholds to contact heat (thermode) and from evoked brain potentials to radiant heat (CO2 laser). Neurophysiol Clin 29: 411-422.
22. Campbell JN, LaMotte RH, (1983) Latency to detection of first pain. Brain Res 266: 203-208.
23. Zaitsev AV, Skorik YA, (2002) Mathematical description of sensorimotor reaction time distribution. Human Physiology 28: 494-497.
24. Hammel HT, Hardy JD, Murgatroyd D, (1956) Spectral transmittance and reflectance of excised human skin. J Appl Physiol 9: 257-264.
25. Hallin RG, Torebjork HE, Wiesenfeld Z, (1982) Nociceptors and warm receptors innervated by C fibres in human skin. J Neurol Neurosurg Psychiatry 45: 313-319.
26. LaMotte RH, Campbell JN, (1978) Comparison of responses of warm and nociceptive C-fiber afferents in monkey with human judgments of thermal pain. J Neurophysiol 41: 509-528.
27. Darian-Smith I, Johnson KO, LaMotte C, Kenins P, Shigenaga Y, et al.(1979) Coding of incremental changes in skin temperature by single warm fibers in the monkey. J Neurophysiol 42: 1316-1331.
28. Darian-Smith I, Johnson KO, LaMotte C, Shigenaga Y, Kenins P, et al.(1979) Warm fibers innervating palmar and digital skin of the monkey: responses to thermal stimuli. J Neurophysiol 42: 1297-1315.
29. Johnson KO, Darian-Smith I, LaMotte C, Johnson B, Oldfield S, (1979) Coding of incremental changes in skin temperature by a population of warm fibers in the monkey: correlation with intensity discrimination in man. J Neurophysiol 42: 1332-1353.
30. Meyer RA, Campbell JN, (1981) Evidence for two distinct classes of unmyelinated nociceptive afferents in monkey. Brain Res 224: 149-152.
31. Plaghki L, Decruynaere C, Van Dooren P, Le Bars D, (2010) The fine tuning of pain thresholds: a sophisticated double alarm system. PLoS ONE 5: e10269.
32. Peng YB, Kenshalo DR, Gracely RH, (2003) Periaqueductal gray-evoked dorsal root reflex is frequency dependent. Brain Res 976: 217-226.
33. Hardy JD, Goodell H, Wolff HG, (1951) The influence of skin temperature upon the pain threshold as evoked by thermal radiation. Science 114: 149-150.
34. Meyer RA, Campbell JN, (1981) Myelinated nociceptive afferents account for the hyperalgesia that follows a burn to the hand. Science 213: 1527-1529.
35. Treede RD, Meyer RA, Raja SN, Campbell JN, (1995) Evidence for two different heat transduction mechanisms in nociceptive primary afferents innervating monkey skin. J Physiol 483 (Pt 3): 747-758.