Binding of islet amyloid polypeptide to supported lipid bilayers and amyloid aggregation at the membranes

Biochemistry

Volumn 51, Issue 35, 2012, Pages 6908-6919

  Sasahara, Kenji ^a   Morigaki, Kenichi ^b,c   Okazaki, Takashi ^b   Hamada, Daizo ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^c KOBE UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID DEPOSITION; BINDING ABILITIES; CELL MASS; CONFORMATIONAL STATE; DIABETES MELLITUS; FLUID LIPID BILAYERS; FLUID MEMBRANE; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; HUMAN ISLETS; ISLETS OF LANGERHANS; LIPID VESICLES; MEMBRANE BINDING; MEMBRANE DYSFUNCTION; MEMBRANE FLUIDITY; MEMBRANE-BOUND; MODEL MEMBRANES; MOLECULAR MECHANISM; PANCREATIC FUNCTIONS; PLANAR BILAYERS; POTENTIAL ABILITY; QUARTZ CRYSTAL MICROBALANCE WITH DISSIPATION MONITORING; SUPPORTED LIPID BILAYERS; TYPE II;

GLYCOPROTEINS; LIPID BILAYERS; PHOTOBLEACHING;

MEMBRANES;

AMYLIN; LIPID;

ADSORPTION; ARTICLE; BINDING AFFINITY; BLEACHING; FIBER; FLUORESCENCE; HUMAN; LIPID MEMBRANE; LIPID VESICLE; MEMBRANE BINDING; MEMBRANE FLUIDITY; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; QUARTZ CRYSTAL MICROBALANCE; RAT; TURBIDITY;

AMINO ACID SEQUENCE; AMYLOID; ANIMALS; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; HUMANS; INSULIN-SECRETING CELLS; ISLET AMYLOID POLYPEPTIDE; LIPID BILAYERS; MEMBRANE FLUIDITY; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN CONFORMATION; QUARTZ CRYSTAL MICROBALANCE TECHNIQUES; RATS; SEQUENCE ALIGNMENT; SOLUBILITY;

RATTUS;

EID: 84865714785     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi300542g     Document Type: Article

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