Premature progesterone rise negatively correlated with live birth rate in IVF cycles with GnRH agonist: An analysis of 2,566 cycles

Fertility and Sterility

Volumn 98, Issue 3, 2012, Pages

  Huang, Rui ^a,b   Fang, Cong ^a   Xu, Shuyi ^c   Yi, Yanhong ^b   Liang, Xiaoyan ^a  

^a THE SIXTH AFFILIATED HOSPITAL OF SUN YAT SEN UNIVERSITY   (China)

^b Women and Children Hospital of Guangdong Province   (China)

^c SUN YAT SEN UNIVERSITY   (China)

Author keywords

GnRH agonist; in vitro fertilization; live birth rate; Premature progesterone rise

Indexed keywords

CHORIONIC GONADOTROPIN; ESTRADIOL; FOLLITROPIN; GONADORELIN AGONIST; LUTEINIZING HORMONE; PROGESTERONE;

ADULT; ARTICLE; CLINICAL PROTOCOL; COHORT ANALYSIS; CORRELATION ANALYSIS; EMBRYO TRANSFER; ESTRADIOL BLOOD LEVEL; FEMALE; FERTILIZATION IN VITRO; FOLLITROPIN BLOOD LEVEL; HUMAN; INCIDENCE; INTRACYTOPLASMIC SPERM INJECTION; LIVE BIRTH; LUTEINIZING HORMONE BLOOD LEVEL; MAJOR CLINICAL STUDY; OOCYTE RETRIEVAL; OUTCOME ASSESSMENT; PREDICTOR VARIABLE; PREMATURE PROGESTERONE RISE; PRIORITY JOURNAL; PROBABILITY; PROGESTERONE BLOOD LEVEL; PUBLIC HOSPITAL; RETROSPECTIVE STUDY;

EID: 84865694987     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2012.05.024     Document Type: Article

References (30)

1. M. Hamori, J.A. Stuckensen, D. Rumpf, T. Kniewald, A. Kniewald, and C.S. Kurz Premature luteinization of follicles during ovarian stimulation for in-vitro fertilization Hum Reprod 2 1987 639 643
2. W. Schoolcraft, E. Sinton, T. Schlenker, D. Huynh, F. Hamilton, and D.R. Meldrum Lower pregnancy rate with premature luteinization during pituitary suppression with leuprolide acetate Fertil Steril 55 1991 563 566
3. K.M. Silverberg, W.N. Burns, D.L. Olive, R.M. Riehl, and R.S. Schenken Serum progesterone levels predict success of in vitro fertilization/embryo transfer in patients stimulated with leuprolide acetate and human menopausal gonadotropins J Clin Endocrinol Metab 73 1991 797 803
4. C.R. Givens, E.D. Schriock, P.V. Dandekar, and M.C. Martin Elevated serum progesterone levels on the day of human chorionic gonadotropin administration do not predict outcome in assisted reproduction cycles Fertil Steril 62 1994 1011 1017
5. F. Martinez, B. Coroleu, E. Clua, R. Tur, R. Buxaderas, and N. Parera Serum progeseterone concentrations on the day of hCG administration can not predict pregnancy in assisted reproduction cycles Reprod Biomed Online 8 2004 183 190
6. E. Bosch, I. Valencia, E. Escudero, J. Crespo, C. Simon, and J. Remohi Premature luteinization during gonadotropin-releasing hormone antagonist cycles and its relationship with in vitro fertilization outcome Fertil Steril 80 2003 1444 1449
7. F.K. Lee, T.H. Lai, T.K. Lin, S.G. Horng, and S.C. Chen Relationship of progesterone/estradiol ratio on day of hCG administration and pregnancy outcomes in high responders undergoing in vitro fertilization Fertil Steril 92 2009 1284 1289
8. E.B. Kiliçdag, B. Haydardedeoglu, T. Cok, S.O. Hacivelioglu, and T. Bagis Premature progesterone elevation impairs implantation and live birth rates in GnRH-agonist IVF/ICSI cycles Arch Gynecol Obstet 281 2010 747 752
9. K.F. Miller, E.J. Behnke, R.L. Arciaga, J.M. Goldberg, N.W. Chin, and S.G. Awadalla The significance of elevated progesterone at the time of human chorionic gonadotropin may be related to luteal support J Assist Reprod Genet 13 1996 698 701
10. T.H. Lai, F.K. Lee, T.K. Lin, S.G. Horng, S.C. Chen, and Y.H. Chen An increased serum progesterone-to-estradiol ratio on the day of human chorionic gonadotropin administration does not have a negative impact on clinical pregnancy rate in women with normal ovarian reserve treated with a long gonadotropin releasing hormone agonist protocol Fertil Steril 92 2009 508 514
11. H.A. Saleh, M.S. Omran, and M. Draz Dose subtle progesterone rise on the day of HCG affect pregnancy rate in long agonist ICSI cycles? J Assist Reprod Genet 26 2009 239 242
12. N. Doldi, E. Marsiglio, A. Destefani, A. Gessi, G. Merati, and A. Ferrari Elevated serum progesterone on the day of HCG administration in IVF is associated with a higher pregnancy rate in polycystic ovary syndrome Hum Reprod 14 1999 601 605
13. C.A. Venetis, E.M. Kolibianakis, E. Papanikolaou, J. Bontis, P. Devroey, and B.C. Tarlatzis Is progesterone elevation on the day of human chorionic gonadotrophin administration associated with the probability of pregnancy in in vitro feritlization? A systematic review and meta-analysis Hum Reprod Update 13 2007 343 355
14. E. Bosch, E. Labarta, J. Crespo, C. Simon, J. Remohi, and J. Jenkins Circulating progesterone levels and ongoing pregnancy rates in controlled ovarian stimulation cycles for in vitro fertilization: analysis of over 4000 cycles Hum Reprod 25 2010 2092 2100
15. E.G. Papanikolaou, E.M. Kolibianakis, C. Pozzobon, P. Tank, H. Tournaye, and C. Bourgain Progesterone rise on the day of human chorionic gonadotropin administration impairs pregnancy outcome in day 3 single-embryo transfer, while has no effect on day 5 single blastocyst transfer Fertil Steril 91 2009 949 952
16. X. Long, C. Pen, and G. Lu Isolation and identification of genes differentially expressed in premature luteinization granulosa cell during controlled ovarian hyperstimulation Fertil Steril 92 2009 1767 1771
17. I. Yovel, Y. Yaron, A. Amit, M.R. Peyser, M.P. David, and A. Kogosowski High progesterone levels adversely affect embryo quality and pregnancy rates in in vitro fertilization and oocyte donation programs Fertil Steril 64 1995 128 131
18. J.N. Hugues, E. Massé-Laroche, J. Reboul-Marty, O. Boîko, C. Meynant, and I. Cédrin-Durnerin Impact of endogenous luteinizing hormone serum levels on progesterone elevation on the day of human chorionic gonadotropin administration Fertil Steril 96 2011 600 604
19. J.S. Younis, M. Matilsky, O. Radin, and M. Ben-Ami Increased progesterone/estradiol ratio in the late follicular phase could be related to low ovarian reserve in in vitro fertilization-embryo transfer cycles with a long gonadotropin-releasing hormone agonist Fertil Steril 76 2001 294 299
20. A.M. Elnashar Progesterone rise on the day of HCG administration (premature luteinization) in IVF: an overdue update J Assist Reprod Genet 27 2010 149 155
21. B. Urman, C. Alatas, S. Aksoy, R. Mercan, A. Isiklar, and B. Balaban Elevated serum progesterone level on the day of human chorionic gonadotropin administration does not adversely affect implantation rates after intracytoplasmic sperm injection and embryo transfer Fertil Steril 72 1999 975 979
22. E.G. Papanikolaou, L. Zepyridis, E. Kolibianakis, G. Grimpizis, G. Pantos, and E. Bili Comparing GnRH-agonist with antagonist IVF cycles, is the clinical outcome affected by the incidence of progesterone elevation A RCT. Hum Reprod 24 Suppl 1 2009 i78
23. B.S. Shapiro, S.T. Daneshmand, F.C. Garner, M. Aguirre, and S. Thomas Large blastocyst diameter, early blastulation, and low preovulatory serum progesterone are dominant predictors of clinical pregnancy in fresh autologous cycles Fertil Steril 90 2008 302 309
24. B.S. Shapiro, S.T. Daneshmand, F.C. Garner, M. Aguirre, C. Hudson, and S. Thomas Embryo cryopreservation rescues cycles with premature luteinization Fertil Steril 93 2010 636 641
25. R. Lahoud, M. Kwik, J. Ryan, M. Al-Jefout, J. Foley, and P. Illingworth Elevated progesterone in GnRH agonist down regulated in vitro fertilisation (IVFICSI) cycles reduces live birth rates but not embryo quality Arch Gynecol Obstet 285 2012 535 540
26. M.A.B. Melo, M. Meseguer, N. Garrido, E. Bosch, A. Pellicer, and J. Remohí The significance of premature luteinization in an oocyte-donation programme Hum Reprod 21 2006 1503 1507
27. I. van Vaerenbergh, H.M. Fatemi, C. Blockeel, L. van Lommel, P. In't Veld, and F. Schuit Progesterone rise on HCG day in GnRH antagonist/rFSH stimulated cycles affects endometrial gene expression Reprod Biomed Online 22 2011 263 271
28. E. Labarta, J.A. Martinez-Conejero, P. Alama, J.A. Horcajadas, A. Pellicer, and C. Simon Endometrial receptivity is affected in women with high circulating progesterone levels at the end of the follicular phase: a functional genomics analysis Hum Reprod 26 2011 1813 1825
29. S. Segal, I. Glatstein, P. McShane, S. Hotamisligil, D. Ezcurra, and R. Carson Premature luteinization and in vitro ferilization outcome in gonadotropin/gonadotropin-releasing hormone antagonist cycles in women with polycystic ovary syndrome Fertil Steril 91 2009 1755 1759
30. K.M. Seow, Y.H. Lin, B.C. Hsieh, L.W. Huang, S.C. Huang, and C.Y. Chen Characteristics of progesterone changes in women with subtle progesterone rise in recombinant follicle-stimulating hormone and gonadotropin-releasing hormone antagonist cycle Gynecol Obstet Invest 70 2010 64 68