Polymeric nanoparticles containing taxanes enhance chemoradiotherapeutic efficacy in non-small cell lung cancer

International Journal of Radiation Oncology Biology Physics

Volumn 84, Issue 1, 2012, Pages

  Jung, Joohee ^a,b   Park, Sung Jin ^a,c   Chung, Hye Kyung ^a   Kang, Hye Won ^d   Lee, Sa Won ^d   Seo, Min Hyo ^d   Park, Heon Joo ^e   Song, Si Yeol ^a   Jeong, Seong Yun ^a   Choi, Eun Kyung ^a,b  

^a University of Ulsan College of Medicine   (South Korea)

^b Duksung Women's University   (South Korea)

^c AGENCY FOR SCIENCE   (Singapore)

^d Samyang Corporation   (South Korea)

^e Inha University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

A549 CELLS; ANTICANCER EFFECTS; AVERAGE DIAMETER; CELLULAR MORPHOLOGY; CHEMORADIATION; CLONOGENIC ASSAYS; COMBINED TREATMENT; HIGH SOLUBILITY; HUMAN CANCER; IN-VIVO; INTRAVENOUS INJECTIONS; NON SMALL CELL LUNG CANCER; POLYMERIC NANOPARTICLES; SIDE EFFECT; SURVIVAL FRACTIONS; SYNERGIC EFFECTS; TAXANES; TUMOR GROWTH;

BIOLOGICAL ORGANS; CHEMORADIOTHERAPY; DISEASES; FLOW CYTOMETRY; IONIZING RADIATION; MAMMALS; MATERIALS PROPERTIES; NANOPARTICLES; TRANSMISSION ELECTRON MICROSCOPY; TUMORS;

POLYMERS;

ANTINEOPLASTIC AGENT; NANOPARTICLE; POLYMER; POLYMERIC NANOPARTICLE; TAXANE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER RADIOTHERAPY; CELL STRUCTURE; CELL SURVIVAL; CLONOGENIC ASSAY; CONTROLLED STUDY; DRUG EFFICACY; FLOW CYTOMETRY; IN VITRO STUDY; IN VIVO STUDY; IONIZING RADIATION; LIGHT SCATTERING; LUNG NON SMALL CELL CANCER; MOUSE; NONHUMAN; PRIORITY JOURNAL; SOLUBILITY; TRANSMISSION ELECTRON MICROSCOPY; TUMOR GROWTH;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; CHEMORADIOTHERAPY; DRUG SYNERGISM; ENDOCYTOSIS; FEASIBILITY STUDIES; HUMANS; LUNG NEOPLASMS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; MICROSCOPY, ELECTRON, SCANNING; NANOCONJUGATES; PACLITAXEL; POLYMERS; RADIATION-SENSITIZING AGENTS; RANDOM ALLOCATION; TAXOIDS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84865691216     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2012.02.030     Document Type: Article

References (17)

1. M.C. Wani, H.L. Taylor, and M.E. Wall Plant antitumor agents. VI. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia J Am Chem Soc 93 1971 2325 2327
2. F. Lavelle, F. Gueritte-Voegelein, and D. Guenard [Taxotere: from yew's needles to clinical practice] Bull cancer 80 1993 326 338
3. R. Pazdur, A.P. Kudelka, and J.J. Kavanagh The taxoids: paclitaxel (Taxol) and docetaxel (Taxotere) Cancer Treat Rev 19 1993 351 386
4. K.H. Downing Structural basis for the interaction of tubulin with proteins and drugs that affect microtubule dynamics Annu Rev Cell Dev Biol 16 2000 89 111
5. D.L. Morse, H. Gray, and C.M. Payne Docetaxel induces cell death through mitotic catastrophe in human breast cancer cells Mol Cancer Ther 4 2005 1495 1504
6. B. van Oijen, M. Pleunis, and F. Erdkamp Toxic dermatitis in patients treated with Taxotere(R) (docetaxel): three case reports Int J Clin Pharmacol Ther 49 2011 46 48
7. K.S. Jothy Basu, A. Bahl, and V. Subramani Normal tissue complication probability of fibrosis in radiotherapy of breast cancer: accelerated partial breast irradiation vs conventional external-beam radiotherapy J Cancer Res Ther 4 2008 126 130
8. M. Creane, C.B. Seymour, and S. Colucci Radiobiological effects of docetaxel (Taxotere): a potential radiation sensitizer Int J Radiat Biol 75 1999 731 737
9. S.W. Lee, D.H. Chang, and M.S. Shim Ionically fixed polymeric nanoparticles as a novel drug carrier Pharm Res 24 2007 1508 1516
10. J. Jung, E.J. Kim, and H.K. Chung c-Myc down-regulation is involved in proteasome inhibitor-mediated enhancement of radiotherapeutic efficacy in non-small cell lung cancer Int J Oncol 40 2012 385 390
11. A.M. Davies, P.N. Lara Jr., and P.C. Mack Docetaxel in non-small cell lung cancer: a review Expert Opinion on Pharmacotherapy 4 2003 553 565
12. http://clinicaltrials.gov/ct2/show/NCT01103791?term=docetaxel+pnp& rank=1.
13. N.K. Ibrahim, B. Samuels, and R. Page Multicenter phase II trial of ABI-007, an albumin-bound paclitaxel, in women with metastatic breast cancer J Clin Oncol 23 2005 6019 6026
14. P. Vishnu, and V. Roy Safety and efficacy of nab-paclitaxel in the treatment of patients with breast cancer Breast Cancer 5 2011 53 65
15. V.L. Galic, T.J. Herzog, and J.D. Wright Paclitaxel poliglumex for ovarian cancer Expert Opin Investig Drugs 20 2011 813 821
16. K.S. Lee, H.C. Chung, and S.A. Im Multicenter phase II trial of Genexol-PM, a Cremophor-free, polymeric micelle formulation of paclitaxel, in patients with metastatic breast cancer Breast Cancer Res Treat 108 2008 241 250
17. S.K. Hobbs, W.L. Monsky, and F. Yuan Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment Proc Natl Acad SciU S A 95 1998 4607 4612