Thrombosis of a mechanical heart valve despite dabigatran

Annals of Internal Medicine

Volumn 157, Issue 4, 2012, Pages 304-

  Chu, John W ^a   Chen, Victor H T ^a   Bunton, Richard ^a  

^a DUNEDIN HOSPITAL   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

DABIGATRAN ETEXILATE; HEPARIN; WARFARIN;

AGED; ANGIOCARDIOGRAPHY; AORTA VALVE REGURGITATION; AORTA VALVE STENOSIS; CASE REPORT; CORONARY ARTERY BYPASS GRAFT; DIASTOLIC HEART MURMUR; DRUG TREATMENT FAILURE; DRUG WITHDRAWAL; DYSPNEA; ECHOCARDIOGRAPHY; FLUOROSCOPY; HUMAN; HYPERLIPIDEMIA; HYPERTENSION; LETTER; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NON ST SEGMENT ELEVATION ACUTE CORONARY SYNDROME; PRESCRIPTION; PRIORITY JOURNAL; PROSTHETIC VALVE THROMBOSIS; SAINT JUDE HEART VALVE PROSTHESIS; SYSTOLIC HEART MURMUR; TRANSESOPHAGEAL ECHOCARDIOGRAPHY; TRANSTHORACIC ECHOCARDIOGRAPHY; UNSTABLE ANGINA PECTORIS;

EID: 84865657840     PISSN: 00034819     EISSN: 15393704     Source Type: Journal    
DOI: 10.7326/0003-4819-157-4-201208210-00026     Document Type: Letter

References (5)

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2. Connolly SJ, Ezekowitz MD, Yusuf S, Eikelboom J, Oldgren J, Parekh A, et al; RE-LY Steering Committee and Investigators. Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med. 2009;361:1139-51.
3. Dabigatran-is there a bleeding problem? Wellington, New Zealand: Medsafe; 2011. Accessed at www.medsafe.govt.nz/profs/PUArticles/DabigatranSept2011.htm on 17 July 2012.
4. Dabigatran Etexilate in Patients With Mechanical Heart Valves [clinical trial]. Accessed at www.clinicaltrials.gov/ct2/show/NCT01452347?term=dabigatran&rank=25 on 17 July 2012.
5. Maegdefessel L, Linde T, Krapiec F, Hamilton K, Steinseifer U, van Ryn J, et al. In vitro comparison of dabigatran, unfractionated heparin, and low-molecular-weight heparin in preventing thrombus formation on mechanical heart valves. Thromb Res. 2010;126:e196-200.