Recapitulation of the association of the Val66Met polymorphism of BDNF gene with BMI in Koreans

Obesity

Volumn 20, Issue 9, 2012, Pages 1871-1875

  Hong, Kyung Won ^a,b   Lim, Ji Eun ^a   Go, Min Jin ^b   Shin Cho, Yoon ^b   Ahn, Younjhin ^b   Han, Bok Ghee ^b   Oh, Bermseok ^a  

^a Kyung Hee University Hospital   (South Korea)

^b Korea National Institute of Health   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; METHIONINE; VALINE;

ADULT; AGED; ARTICLE; ASIAN; BODY MASS; BRAIN DERIVED NEUROTROPHIC FACTOR GENE; CANNABIS SMOKING; CONTROLLED STUDY; FEMALE; GENE; GENETIC ASSOCIATION; GENETIC LINKAGE; GENETIC RISK; HUMAN; KOREA; MALE; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGED; ANALYSIS OF VARIANCE; APPETITE REGULATION; ASIAN CONTINENTAL ANCESTRY GROUP; BODY MASS INDEX; BRAIN-DERIVED NEUROTROPHIC FACTOR; FEMALE; GENOTYPE; HUMANS; MALE; METHIONINE; MIDDLE AGED; MUTATION; POLYMORPHISM, SINGLE NUCLEOTIDE; SMOKING; VALINE; WEIGHT LOSS;

EID: 84865618964     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1038/oby.2011.352     Document Type: Article

References (22)

1. Guh DP, Zhang W, Bansback N et al. The incidence of co-morbidities related to obesity and overweight: a systematic review and meta-analysis. BMC Public Health 2009;9:88.
2. Yoon KH, Lee JH, Kim JW et al. Epidemic obesity and type 2 diabetes in Asia. Lancet 2006;368:1681-1688.
3. Jee SH, Sull JW, Park J et al. Body-mass index and mortality in Korean men and women. N Engl J Med 2006;355:779-787. (Pubitemid 44285583)
4. Lebrun B, Bariohay B, Moyse E, Jean A. Brain-derived neurotrophic factor (BDNF) and food intake regulation: a minireview. Auton Neurosci 2006;126-127:30-38. (Pubitemid 43833352)
5. Lapchak PA, Hefti F. BDNF and NGF treatment in lesioned rats: effects on cholinergic function and weight gain. Neuroreport 1992;3:405-408.
6. Pelleymounter MA, Cullen MJ, Wellman CL. Characteristics of BDNFinduced weight loss. Exp Neurol 1995;131:229-238.
7. Kernie SG, Liebl DJ, Parada LF. BDNF regulates eating behavior and locomotor activity in mice. EMBO J 2000;19:1290-1300. (Pubitemid 30151025)
8. Lyons WE, Mamounas LA, Ricaurte GA et al. Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities. Proc Natl Acad Sci USA 1999;96:15239-15244. (Pubitemid 30019796)
9. Gunstad J, Schofield P, Paul RH et al. BDNF Val66Met polymorphism is associated with body mass index in healthy adults. Neuropsychobiology 2006;53:153-156. (Pubitemid 43854175)
10. Shugart YY, Chen L, Day IN et al. Two British women studies replicated the association between the Val66Met polymorphism in the brain-derived neurotrophic factor (BDNF) and BMI. Eur J Hum Genet 2009;17:1050-1055.
11. Thorleifsson G, Walters GB, Gudbjartsson DF et al. Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. Nat Genet 2009;41:18-24.
12. Friedel S, Horro FF, Wermter AK et al. Mutation screen of the brain derived neurotrophic factor gene (BDNF): identification of several genetic variants and association studies in patients with obesity, eating disorders, and attention-deficit/hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet 2005;132 B: 96-99. (Pubitemid 40066204)
13. Lang UE, Sander T, Lohoff FW et al. Association of the met66 allele of brainderived neurotrophic factor (BDNF) with smoking. Psychopharmacology (Berl) 2007;190:433-439. (Pubitemid 46204460)
14. Bhang SY, Choi SW, Ahn JH. Changes in plasma brain-derived neurotrophic factor levels in smokers after smoking cessation. Neurosci Lett 2010;468:7-11.
15. Cho YS, Go MJ, Kim YJ et al. A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits. Nat Genet 2009;41:527-534.
16. Rabbee N, Speed TP. A genotype calling algorithm for affymetrix SNP arrays. Bioinformatics 2006;22:7-12. (Pubitemid 43057002)
17. WTCCC. Genome-wide association study of 14, 000 cases of seven common diseases and 3, 000 shared controls. Nature 2007;447:661-678.
18. Hotta K, Nakamura M, Nakamura T et al. Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population. J Hum Genet 2009;54:727-731.
19. Ng MC, Tam CH, So WY et al. Implication of genetic variants near NEGR1, SEC16B, TMEM18, ETV5/DGKG, GNPDA2, LIN7C/BDNF, MTCH2, BCDIN3D/FAIM2, SH2B1, FTO, MC4R, and KCTD15 with obesity and type 2 diabetes in 7705 Chinese. J Clin Endocrinol Metab 2010;95:2418-2425.
20. Croteau-Chonka DC, Marvelle AF, Lange EM et al. Genome-wide association study of anthropometric traits and evidence of interactions with age and study year in Filipino women. Obesity (Silver Spring) 2011;19:1019-1027.
21. Wu L, Xi B, Zhang M et al. Associations of six single nucleotide polymorphisms in obesity-related genes with BMI and risk of obesity in Chinese children. Diabetes 2010;59:3085-3089.
22. Egan MF, Kojima M, Callicott JH et al. The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell 2003;112:257-269. (Pubitemid 36144114)