Ventilatory and cardiocirculatory exercise profiles in COPD: The role of pulmonary hypertension

Chest

Volumn 142, Issue 5, 2012, Pages 1166-1174

  Boerrigter, Bart G ^a   Bogaard, Harm J ^a   Trip, Pia ^a   Groepenhoff, Herman ^a   Rietema, Heleen ^a   Holverda, Sebastiaan ^a   Boonstra, Anco ^a   Postmus, Pieter E ^a   Westerhof, Nico ^a   Vonk Noordegraaf, Anton ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTERIAL CARBON DIOXIDE TENSION; ARTICLE; BREATHING RESERVE; CARDIOPULMONARY EXERCISE TEST; CHRONIC OBSTRUCTIVE LUNG DISEASE; CIRCULATION; CLINICAL ARTICLE; DISEASE SEVERITY; EXERCISE; FEMALE; HUMAN; LUNG VENTILATION; LUNG VOLUME; MALE; MIXED VENOUS OXYGEN SATURATION; OXYGEN SATURATION; PRIORITY JOURNAL; PULMONARY HYPERTENSION;

EID: 84865605188     PISSN: 00123692     EISSN: 19313543     Source Type: Journal    
DOI: 10.1378/chest.11-2798     Document Type: Article

References (40)

1. Debigaré R, Maltais F. The major limitation to exercise performance in COPD is lower limb muscle dysfunction. J Appl Physiol . 2008;105(2):751-753.
2. O'Donnell DE, Webb KA. The major limitation to exercise performance in COPD is dynamic hyperinflation. J Appl Physiol . 2008;105 (2) :753-755.
3. Aliverti A, Macklem PT . The major limitation to exercise performance in COPD is inadequate energy supply to the respiratory and locomotor muscles. J Appl Physiol 2008; 105(2):749-751.
4. . Morrison DA, Adcock K, Collins CM, Goldman S, Caldwell JH, Schwarz MI . Right ventricular dysfunction and the exercise limitation of chronic obstructive pulmonary disease. J Am Coll Cardiol. 1987;9(6):1219-1229. (Pubitemid 17083518)
5. Holverda S, Rietema H, Westerhof N, et al . Stroke volume increase to exercise in chronic obstructive pulmonary disease is limited by increased pulmonary artery pressure. Heart. 2009;95(2):137-141.
6. . Light RW, Mintz HM, Linden GS, Brown SE. Hemodynamics of patients with severe chronic obstructive pulmonary disease during progressive upright exercise. Am Rev Respir Dis. 1984;130(3):391-395. (Pubitemid 14029765)
7. . Mahler DA, Brent BN, Loke J, Zaret BL, Matthay RA. Right ventricular performance and central circulatory hemodynamics during upright exercise in patients with chronic obstructive pulmonary disease. Am Rev Respir Dis. 1984;130(5):722-729. (Pubitemid 15209549)
8. Matthay RA, Arroliga AC, Wiedemann HP, Schulman DS, Mahler DA. Right ventricular function at rest and during exercise in chronic obstructive pulmonary disease. Chest. 1992;101(suppl 5):255S-262S.
9. . Stewart RI, Lewis CM. Cardiac output during exercise in patients with COPD. Chest. 1986;89(2):199-205. (Pubitemid 16156415)
10. Chaouat A, Naeije R, Weitzenblum E. Pulmonary hypertension in COPD. Eur Respir J. 2008;32(5):1371-1385.
11. Blanco I, Gimeno E, Munoz PA, et al. Hemodynamic and gas exchange effects of sildenafil in patients with chronic obstructive pulmonary disease and pulmonary hypertension. Am J Respir Crit Care Med. 2010;181(3):270-278.
12. Rietema H, Holverda S, Bogaard HJ, et al. Sildenafil treatment in COPD does not affect stroke volume or exercise capacity. Eur Respir J. 2008;31(4):759-764.
13. . Chaouat A, Bugnet AS, Kadaoui N, et al. Severe pulmonary hypertension and chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2005;172(2):189-194. (Pubitemid 40981192)
14. . Thabut G, Dauriat G, Stern JB, et al. Pulmonary hemodynamics in advanced COPD candidates for lung volume reduction surgery or lung transplantation. Chest. 2005;127(5):1531-1536. (Pubitemid 46218776)
15. . Celli BR, MacNee W; ATS/ERS Task Force. Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper. Eur Respir J. 2004;23(6):932-946. (Pubitemid 38807371)
16. . Holverda S, Rietema H, Bogaard HJ, et al. Acute effects of sildenafil on exercise pulmonary hemodynamics and capacity in patients with COPD. Pulm Pharmacol Ther. 2008;21(3):558-564. (Pubitemid 351625938)
17. Boerrigter B, Trip P, Bogaard HJ, et al. Right atrial pressure affects the interaction between lung mechanics and right ventricular function in spontaneously breathing COPD patients. PLoS ONE. 2012;7(1):e30208.
18. Galiè N, Hoeper MM, Humbert M, et al Task Force for Diagnosis and Treatment of Pulmonary Hypertension of European Society of Cardiology (ESC); European Respiratory Society (ERS); International Society of Heart and Lung Trans plantation (ISHLT). Guidelines for the diagnosis and treatment of pulmonary hypertension. Eur Respir J. 2009;34(6):1219-1263.
19. . Meyer FJ, Ewert R, Hoeper MM, et al German PPH Study Group. Peripheral airway obstruction in primary pulmonary hypertension. Thorax. 2002;57(6):473-476. (Pubitemid 34627977)
20. . Macintyre N, Crapo RO, Viegi G, et al. Standardisation of the single-breath determination of carbon monoxide uptake in the lung. Eur Respir J. 2005;26(4):720-735. (Pubitemid 41448672)
21. . Miller MR, Hankinson J, Brusasco V, et al ATS/ERS Task Force. Standardisation of spirometry. Eur Respir J. 2005;26(2):319-338. (Pubitemid 41079078)
22. . Wanger J, Clausen JL, Coates A, et al. Standardisation of the measurement of lung volumes. Eur Respir J. 2005;26(3):511-522. (Pubitemid 41264217)
23. American Thoracic Society; American College of Chest Physicians. ATS/ACCP statement on cardiopulmonary exercise testing. Am J Respir Crit Care Med. 2003;167(2):211-277.
24. . Beaver WL, Wasserman K, Whipp BJ. A new method for detecting anaerobic threshold by gas exchange. J Appl Physiol. 1986;60(6):2020-2027. (Pubitemid 16066969)
25. Wasserman K, Hansen J, Sue D, Stringer W, Whipp B. Principles of Exercise Testing and Interpretation. Philadelphia, PA: Lippincott Williams & Wilkins; 2005.
26. ATS Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories. ATS statement: guidelines for the six-minute walk test. Am J Respir Crit Care Med. 2002;166(1):111-117.
27. . Wagner PD, Gale GE, Moon RE, Torre-Bueno JR, Stolp BW, Saltzman HA. Pulmonary gas exchange in humans exercising at sea level and simulated altitude. J Appl Physiol. 1986;61(1):260-270. (Pubitemid 16055687)
28. Granath A, Jonsson B, Strandell T. Circulation in healthy old men, studied by right heart catheterization at rest and during exercise in supine and sitting position. Acta Med Scand. 1964;176:425-446.
29. Laveneziana P, Webb KA, Ora J, Wadell K, O'Donnell DE. Evolution of dyspnea during exercise in chronic obstructive pulmonary disease:impact of critical volume constraints. Am J Respir Crit Care Med. 2011;184(12):1367-1373.
30. . Tenney SM, Mithoefer JC. The relationship of mixed venous oxygenation to oxygen transport: with special reference to adaptations to high altitude and pulmonary diseases. Am Rev Respir Dis. 1982;125(4):474-479. (Pubitemid 12154496)
31. . Richardson RS, Sheldon J, Poole DC, Hopkins SR, Ries AL, Wagner PD. Evidence of skeletal muscle metabolic reserve during whole body exercise in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 1999;159(3):881-885. (Pubitemid 29137789)
32. . Hoeper MM, Pletz MW, Golpon H, Welte T. Prognostic value of blood gas analyses in patients with idiopathic pulmonary arterial hypertension. Eur Respir J. 2007;29(5):944-950. (Pubitemid 46711899)
33. . Velez-Roa S, Ciarka A, Najem B, Vachiery JL, Naeije R, van de Borne P. Increased sympathetic nerve activity in pulmonary artery hypertension. Circulation. 2004;110(10):1308-1312. (Pubitemid 39202350)
34. Holverda S, Bogaard HJ, Groepenhoff H, Postmus PE, Boonstra A, Vonk-Noordegraaf A. Cardiopulmonary exercise test characteristics in patients with chronic obstructive pulmonary disease and associated pulmonary hypertension. Respiration. 2008;76(2):160-167.
35. Pynnaert C, Lamotte M, Naeije R. Aerobic exercise capacity in COPD patients with and without pulmonary hypertension. Respir Med. 2010;104(1):121-126.
36. . Biernacki W, Flenley DC, Muir AL, MacNee W. Pulmonary hypertension and right ventricular function in patients with COPD. Chest. 1988;94(6):1169-1175. (Pubitemid 19002775)
37. Shaw DB, Grover RF, Reeves JT, Blount G Jr. Pulmonary circulation in chronic bronchitis and emphysema. Br Heart J. 1965;27(5):674-683.
38. Stolz D, Rasch H, Linka A, et al. A randomised, controlled trial of bosentan in severe COPD. Eur Respir J. 2008;32(3): 619-628.
39. . Sue DY, Wasserman K, Moricca RB, Casaburi R. Metabolic acidosis during exercise in patients with chronic obstructive pulmonary disease. Use of the V-slope method for anaerobic threshold determination. Chest. 1988;94(5):931-938. (Pubitemid 18264631)
40. . Midorikawa J, Hida W, Taguchi O, et al. Lack of ventilatory threshold in patients with chronic obstructive pulmonary disease. Respiration. 1997;64(1):76-80. (Pubitemid 27055460)