메뉴 건너뛰기




Volumn 110, Issue 6 SUPPL., 2012, Pages S32-S38

The potential of biomarkers in pulmonary arterial hypertension

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; BRAIN NATRIURETIC PEPTIDE; C REACTIVE PROTEIN; ENDOTHELIN; GROWTH DIFFERENTIATION FACTOR; INTERLEUKIN 2; ISOPROSTANE; NATRIURETIC PEPTIDE RECEPTOR A; NITRIC OXIDE; PROSTAGLANDIN; TROPONIN;

EID: 84865529555     PISSN: 00029149     EISSN: 18791913     Source Type: Journal    
DOI: 10.1016/j.amjcard.2012.06.014     Document Type: Article
Times cited : (40)

References (70)
  • 1
    • 70049112901 scopus 로고    scopus 로고
    • Guidelines for the diagnosis and treatment of pulmonary hypertension: The Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT)
    • N. Galie, M.M. Hoeper, M. Humbert, A. Torbicki, J.L. Vachiery, J.A. Barbera, M. Beghetti, P. Corris, S. Gaine, J.S. Gibbs Guidelines for the diagnosis and treatment of pulmonary hypertension: The Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT) Eur Heart J 30 2009 2493 2537
    • (2009) Eur Heart J , vol.30 , pp. 2493-2537
    • Galie, N.1    Hoeper, M.M.2    Humbert, M.3    Torbicki, A.4    Vachiery, J.L.5    Barbera, J.A.6    Beghetti, M.7    Corris, P.8    Gaine, S.9    Gibbs, J.S.10
  • 3
    • 0035100888 scopus 로고    scopus 로고
    • Biomarkers and surrogate endpoints: Preferred definitions and conceptual framework
    • Biomarkers Definition Working Group
    • Biomarkers Definition Working Group Biomarkers and surrogate endpoints: preferred definitions and conceptual framework Clin Pharmacol Ther 69 2001 89 95
    • (2001) Clin Pharmacol Ther , vol.69 , pp. 89-95
  • 4
    • 78651394465 scopus 로고    scopus 로고
    • Bring on the biomarkers
    • G. Poste Bring on the biomarkers Nature 469 2011 156 157
    • (2011) Nature , vol.469 , pp. 156-157
    • Poste, G.1
  • 6
    • 0142120730 scopus 로고    scopus 로고
    • Novel risk markers and clinical practice
    • T. Manolio Novel risk markers and clinical practice N Engl J Med 349 2003 1587 1589
    • (2003) N Engl J Med , vol.349 , pp. 1587-1589
    • Manolio, T.1
  • 7
    • 33845700525 scopus 로고    scopus 로고
    • The limitations of risk factors as prognostic tools
    • J.H. Ware The limitations of risk factors as prognostic tools N Engl J Med 355 2006 2615 2617
    • (2006) N Engl J Med , vol.355 , pp. 2615-2617
    • Ware, J.H.1
  • 8
    • 79952044706 scopus 로고    scopus 로고
    • The utility of troponin measurement to detect myocardial infarction: Review of the current findings
    • M.A. Daubert, A. Jeremias The utility of troponin measurement to detect myocardial infarction: review of the current findings Vasc Health Risk Manag 6 2010 691 699
    • (2010) Vasc Health Risk Manag , vol.6 , pp. 691-699
    • Daubert, M.A.1    Jeremias, A.2
  • 9
    • 5344233478 scopus 로고    scopus 로고
    • Pulmonary arterial hypertension
    • H.W. Farber, J. Loscalzo Pulmonary arterial hypertension N Engl J Med 351 2004 1655 1665
    • (2004) N Engl J Med , vol.351 , pp. 1655-1665
    • Farber, H.W.1    Loscalzo, J.2
  • 12
    • 78650836034 scopus 로고    scopus 로고
    • Clinical perspective: Biomarkers in pulmonary arterial hypertension
    • G.A. Heresi Clinical perspective: biomarkers in pulmonary arterial hypertension Int J Clin Pract Suppl 169 2011 5 7
    • (2011) Int J Clin Pract Suppl , vol.169 , pp. 5-7
    • Heresi, G.A.1
  • 14
    • 0029055964 scopus 로고
    • Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension
    • A. Giaid, D. Saleh Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension N Engl J Med 333 1995 214 221
    • (1995) N Engl J Med , vol.333 , pp. 214-221
    • Giaid, A.1    Saleh, D.2
  • 15
    • 0031856005 scopus 로고    scopus 로고
    • High expression of endothelial nitric oxide synthase in plexiform lesions of pulmonary hypertension
    • N.A. Mason, D.R. Springall, M. Burke, J. Pollock, G. Mikhail, M.H. Yacoub, J.M. Polak High expression of endothelial nitric oxide synthase in plexiform lesions of pulmonary hypertension J Pathol 185 1998 313 318
    • (1998) J Pathol , vol.185 , pp. 313-318
    • Mason, N.A.1    Springall, D.R.2    Burke, M.3    Pollock, J.4    Mikhail, G.5    Yacoub, M.H.6    Polak, J.M.7
  • 19
    • 0031019854 scopus 로고    scopus 로고
    • Exhaled nitric oxide during exercise in primary pulmonary hypertension and pulmonary fibrosis
    • M.S. Riley, J. Porszasz, J. Miranda, M.P. Engelen, B. Brundage, K. Wasserman Exhaled nitric oxide during exercise in primary pulmonary hypertension and pulmonary fibrosis Chest 111 1997 44 50
    • (1997) Chest , vol.111 , pp. 44-50
    • Riley, M.S.1    Porszasz, J.2    Miranda, J.3    Engelen, M.P.4    Brundage, B.5    Wasserman, K.6
  • 20
    • 0032855452 scopus 로고    scopus 로고
    • Effect of nebulized epoprostenol (prostacyclin) on exhaled nitric oxide in patients with pulmonary hypertension due to congenital heart disease and in normal controls
    • I.A. Forrest, T. Small, P.A. Corris Effect of nebulized epoprostenol (prostacyclin) on exhaled nitric oxide in patients with pulmonary hypertension due to congenital heart disease and in normal controls Clin Sci (Lond) 97 1999 99 102
    • (1999) Clin Sci (Lond) , vol.97 , pp. 99-102
    • Forrest, I.A.1    Small, T.2    Corris, P.A.3
  • 22
    • 0035722661 scopus 로고    scopus 로고
    • High levels of nitric oxide in individuals with pulmonary hypertension receiving epoprostenol therapy
    • M. Ozkan, R.A. Dweik, D. Laskowski, A.C. Arroliga, S.C. Erzurum High levels of nitric oxide in individuals with pulmonary hypertension receiving epoprostenol therapy Lung 179 2001 233 243
    • (2001) Lung , vol.179 , pp. 233-243
    • Ozkan, M.1    Dweik, R.A.2    Laskowski, D.3    Arroliga, A.C.4    Erzurum, S.C.5
  • 23
    • 0035171979 scopus 로고    scopus 로고
    • Big endothelin-1 and endothelin-1 plasma levels are correlated with the severity of primary pulmonary hypertension
    • C. Rubens, R. Ewert, M. Halank, R. Wensel, H.D. Orzechowski, H.P. Schultheiss, G. Hoeffken Big endothelin-1 and endothelin-1 plasma levels are correlated with the severity of primary pulmonary hypertension Chest 120 2001 1562 1569
    • (2001) Chest , vol.120 , pp. 1562-1569
    • Rubens, C.1    Ewert, R.2    Halank, M.3    Wensel, R.4    Orzechowski, H.D.5    Schultheiss, H.P.6    Hoeffken, G.7
  • 24
    • 33846309982 scopus 로고    scopus 로고
    • Endothelin-1/endothelin-3 ratio: A potential prognostic factor of pulmonary arterial hypertension
    • D. Montani, R. Souza, C. Binkert, W. Fischli, G. Simonneau, M. Clozel, M. Humbert Endothelin-1/endothelin-3 ratio: a potential prognostic factor of pulmonary arterial hypertension Chest 131 2007 101 108
    • (2007) Chest , vol.131 , pp. 101-108
    • Montani, D.1    Souza, R.2    Binkert, C.3    Fischli, W.4    Simonneau, G.5    Clozel, M.6    Humbert, M.7
  • 25
    • 27144471653 scopus 로고    scopus 로고
    • Von Willebrand factor independently predicts long-term survival in patients with pulmonary arterial hypertension
    • S.M. Kawut, E.M. Horn, K.K. Berekashvili, A.C. Widlitz, E.B. Rosenzweig, R.J. Barst von Willebrand factor independently predicts long-term survival in patients with pulmonary arterial hypertension Chest 128 2005 2355 2362
    • (2005) Chest , vol.128 , pp. 2355-2362
    • Kawut, S.M.1    Horn, E.M.2    Berekashvili, K.K.3    Widlitz, A.C.4    Rosenzweig, E.B.5    Barst, R.J.6
  • 26
    • 0031765161 scopus 로고    scopus 로고
    • Circulating von Willebrand factor antigen as a predictor of short-term prognosis in pulmonary hypertension
    • A.A. Lopes, N.Y. Maeda Circulating von Willebrand factor antigen as a predictor of short-term prognosis in pulmonary hypertension Chest 114 1998 1276 1282
    • (1998) Chest , vol.114 , pp. 1276-1282
    • Lopes, A.A.1    Maeda, N.Y.2
  • 33
    • 63049136565 scopus 로고    scopus 로고
    • C-reactive protein: A new predictor of adverse outcome in pulmonary arterial hypertension
    • R. Quarck, T. Nawrot, B. Meyns, M. Delcroix C-reactive protein: a new predictor of adverse outcome in pulmonary arterial hypertension J Am Coll Cardiol 53 2009 1211 1218
    • (2009) J Am Coll Cardiol , vol.53 , pp. 1211-1218
    • Quarck, R.1    Nawrot, T.2    Meyns, B.3    Delcroix, M.4
  • 36
    • 15744376499 scopus 로고    scopus 로고
    • Oxidant stress but not thromboxane decreases with epoprostenol therapy
    • I.M. Robbins, J.D. Morrow, B.W. Christman Oxidant stress but not thromboxane decreases with epoprostenol therapy Free Radic Biol Med 38 2005 568 574
    • (2005) Free Radic Biol Med , vol.38 , pp. 568-574
    • Robbins, I.M.1    Morrow, J.D.2    Christman, B.W.3
  • 37
    • 0032126807 scopus 로고    scopus 로고
    • Pulmonary hypertension and inflammation
    • R.M. Tuder, N.F. Voelkel Pulmonary hypertension and inflammation J Lab Clin Med 132 1998 16 24
    • (1998) J Lab Clin Med , vol.132 , pp. 16-24
    • Tuder, R.M.1    Voelkel, N.F.2
  • 38
    • 77954458442 scopus 로고    scopus 로고
    • CXC-chemokine ligand 10 in idiopathic pulmonary arterial hypertension: Marker of improved survival
    • G.A. Heresi, M. Aytekin, J. Newman, R.A. Dweik CXC-chemokine ligand 10 in idiopathic pulmonary arterial hypertension: marker of improved survival Lung 188 2010 191 197
    • (2010) Lung , vol.188 , pp. 191-197
    • Heresi, G.A.1    Aytekin, M.2    Newman, J.3    Dweik, R.A.4
  • 40
    • 0031862908 scopus 로고    scopus 로고
    • Plasma brain natriuretic peptide as a biochemical marker of high left ventricular end-diastolic pressure in patients with symptomatic left ventricular dysfunction
    • K. Maeda, T. Tsutamoto, A. Wada, T. Hisanaga, M. Kinoshita Plasma brain natriuretic peptide as a biochemical marker of high left ventricular end-diastolic pressure in patients with symptomatic left ventricular dysfunction Am Heart J 135 1998 825 832
    • (1998) Am Heart J , vol.135 , pp. 825-832
    • Maeda, K.1    Tsutamoto, T.2    Wada, A.3    Hisanaga, T.4    Kinoshita, M.5
  • 47
    • 27144522525 scopus 로고    scopus 로고
    • Characterization of brain natriuretic peptide in long-term follow-up of pulmonary arterial hypertension
    • H.H. Leuchte, M. Holzapfel, R.A. Baumgartner, C. Neurohr, M. Vogeser, J. Behr Characterization of brain natriuretic peptide in long-term follow-up of pulmonary arterial hypertension Chest 128 2005 2368 2374
    • (2005) Chest , vol.128 , pp. 2368-2374
    • Leuchte, H.H.1    Holzapfel, M.2    Baumgartner, R.A.3    Neurohr, C.4    Vogeser, M.5    Behr, J.6
  • 49
    • 33646476400 scopus 로고    scopus 로고
    • Serum N-terminal brain natriuretic peptide as a prognostic parameter in patients with pulmonary hypertension
    • A. Fijalkowska, M. Kurzyna, A. Torbicki, G. Szewczyk, M. Florczyk, P. Pruszczyk, M. Szturmowicz Serum N-terminal brain natriuretic peptide as a prognostic parameter in patients with pulmonary hypertension Chest 129 2006 1313 1321
    • (2006) Chest , vol.129 , pp. 1313-1321
    • Fijalkowska, A.1    Kurzyna, M.2    Torbicki, A.3    Szewczyk, G.4    Florczyk, M.5    Pruszczyk, P.6    Szturmowicz, M.7
  • 50
    • 33847112145 scopus 로고    scopus 로고
    • N-terminal pro-brain natriuretic peptide and renal insufficiency as predictors of mortality in pulmonary hypertension
    • H.H. Leuchte, M. El Nounou, J.C. Tuerpe, B. Hartmann, R.A. Baumgartner, M. Vogeser, O. Muehling, J. Behr N-terminal pro-brain natriuretic peptide and renal insufficiency as predictors of mortality in pulmonary hypertension Chest 131 2007 402 409
    • (2007) Chest , vol.131 , pp. 402-409
    • Leuchte, H.H.1    El Nounou, M.2    Tuerpe, J.C.3    Hartmann, B.4    Baumgartner, R.A.5    Vogeser, M.6    Muehling, O.7    Behr, J.8
  • 51
    • 46449124591 scopus 로고    scopus 로고
    • Ambrisentan in Pulmonary Arterial Hypertension, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Efficacy Studies (ARIES) Group: Ambrisentan for the treatment of pulmonary arterial hypertension: Results of the Ambrisentan in Pulmonary Arterial Hypertension, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Efficacy (ARIES) Study 1 and 2
    • N. Gali, H. Olschewski, R.J. Oudiz, F. Torres, A. Frost, H.A. Ghofrani, D.B. Badesch, M.D. McGoon, V.V. McLaughlin, E.B. Roecker Ambrisentan in Pulmonary Arterial Hypertension, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Efficacy Studies (ARIES) Group Ambrisentan for the treatment of pulmonary arterial hypertension: results of the Ambrisentan in Pulmonary Arterial Hypertension, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Efficacy (ARIES) Study 1 and 2 Circulation 117 2008 3010 3019
    • (2008) Circulation , vol.117 , pp. 3010-3019
    • Gali, N.1    Olschewski, H.2    Oudiz, R.J.3    Torres, F.4    Frost, A.5    Ghofrani, H.A.6    Badesch, D.B.7    McGoon, M.D.8    McLaughlin, V.V.9    Roecker, E.B.10
  • 52
    • 45249119855 scopus 로고    scopus 로고
    • Treatment of patients with mildly symptomatic pulmonary arterial hypertension with bosentan (EARLY study): A double-blind, randomised controlled trial
    • N. Gali, L. Rubin, M. Hoeper, P. Jansa, H. Al-Hiti, G. Meyer, E. Chiossi, A. Kusic-Pajic, G. Simonneau Treatment of patients with mildly symptomatic pulmonary arterial hypertension with bosentan (EARLY study): a double-blind, randomised controlled trial Lancet 371 2008 2093 2100
    • (2008) Lancet , vol.371 , pp. 2093-2100
    • Gali, N.1    Rubin, L.2    Hoeper, M.3    Jansa, P.4    Al-Hiti, H.5    Meyer, G.6    Chiossi, E.7    Kusic-Pajic, A.8    Simonneau, G.9
  • 53
    • 57449103127 scopus 로고    scopus 로고
    • Bosentan for treatment of inoperable chronic thromboembolic pulmonary hypertension: BENEFiT (Bosentan Effects in iNopErable Forms of chronIc Thromboembolic pulmonary hypertension), a randomized, placebo-controlled trial
    • X. Jais, A.M. D'Armini, P. Jansa, A. Torbicki, M. Delcroix, H.A. Ghofrani, M.M. Hoeper, I.M. Lang, E. Mayer, J. Pepke-Zaba Bosentan for treatment of inoperable chronic thromboembolic pulmonary hypertension: BENEFiT (Bosentan Effects in iNopErable Forms of chronIc Thromboembolic pulmonary hypertension), a randomized, placebo-controlled trial J Am Coll Cardiol 52 2008 2127 2134
    • (2008) J Am Coll Cardiol , vol.52 , pp. 2127-2134
    • Jais, X.1    D'Armini, A.M.2    Jansa, P.3    Torbicki, A.4    Delcroix, M.5    Ghofrani, H.A.6    Hoeper, M.M.7    Lang, I.M.8    Mayer, E.9    Pepke-Zaba, J.10
  • 56
    • 79960681673 scopus 로고    scopus 로고
    • Sensitive and high sensitivity next generation cardiac troponin assays: More than just a name
    • R.H. Christenson, D. Phillips Sensitive and high sensitivity next generation cardiac troponin assays: more than just a name Pathology 43 2011 213 219
    • (2011) Pathology , vol.43 , pp. 213-219
    • Christenson, R.H.1    Phillips, D.2
  • 57
    • 77956220651 scopus 로고    scopus 로고
    • High-sensitive troponin T: A novel biomarker for prognosis and disease severity in patients with pulmonary arterial hypertension
    • A. Filusch, E. Giannitsis, H.A. Katus, F.J. Meyer High-sensitive troponin T: a novel biomarker for prognosis and disease severity in patients with pulmonary arterial hypertension Clin Sci (Lond) 119 2010 207 213
    • (2010) Clin Sci (Lond) , vol.119 , pp. 207-213
    • Filusch, A.1    Giannitsis, E.2    Katus, H.A.3    Meyer, F.J.4
  • 58
    • 84860333319 scopus 로고    scopus 로고
    • Sensitive cardiac troponin i predicts poor outcomes in pulmonary arterial hypertension
    • G.A. Heresi, W.H. Tang, M. Aytekin, J. Hammel, S.L. Hazen, R.A. Dweik Sensitive cardiac troponin I predicts poor outcomes in pulmonary arterial hypertension Eur Respir J 39 2012 939 944
    • (2012) Eur Respir J , vol.39 , pp. 939-944
    • Heresi, G.A.1    Tang, W.H.2    Aytekin, M.3    Hammel, J.4    Hazen, S.L.5    Dweik, R.A.6
  • 61
    • 0012135331 scopus 로고
    • An estimation of hepatic blood flow and splanchnic oxygen consumption in heart failure
    • J.D. Myers, J.B. Hickam An estimation of hepatic blood flow and splanchnic oxygen consumption in heart failure J Clin Invest 27 1948 620 627
    • (1948) J Clin Invest , vol.27 , pp. 620-627
    • Myers, J.D.1    Hickam, J.B.2
  • 62
    • 0001554117 scopus 로고
    • Alterations in indices of liver function in congestive heart failure with particular reference to serum enzymes
    • S.M. Richman, A.J. Delman, D. Crob Alterations in indices of liver function in congestive heart failure with particular reference to serum enzymes Am J Med 30 1961 211 255
    • (1961) Am J Med , vol.30 , pp. 211-255
    • Richman, S.M.1    Delman, A.J.2    Crob, D.3
  • 63
    • 77951040904 scopus 로고    scopus 로고
    • Bilirubin as a prognostic marker in patients with pulmonary arterial hypertension
    • Y. Takeda, Y. Takeda, S. Tomimoto, R. Tami, H. Narita, G. Kimura Bilirubin as a prognostic marker in patients with pulmonary arterial hypertension BMC Pulm Med 10 2010 22
    • (2010) BMC Pulm Med , vol.10 , pp. 22
    • Takeda, Y.1    Takeda, Y.2    Tomimoto, S.3    Tami, R.4    Narita, H.5    Kimura, G.6
  • 65
    • 43449136481 scopus 로고    scopus 로고
    • Association of serum creatinine with abnormal hemodynamics and mortality in pulmonary arterial hypertension
    • S.J. Shah, T. Thenappan, S. Rich, L. Tian, S.L. Archer, M. Gomberg-Maitland Association of serum creatinine with abnormal hemodynamics and mortality in pulmonary arterial hypertension Circulation 117 2008 2475 2483
    • (2008) Circulation , vol.117 , pp. 2475-2483
    • Shah, S.J.1    Thenappan, T.2    Rich, S.3    Tian, L.4    Archer, S.L.5    Gomberg-Maitland, M.6
  • 67
    • 77957698019 scopus 로고    scopus 로고
    • Plasma levels of high-density lipoprotein cholesterol and outcomes in pulmonary arterial hypertension
    • G.A. Heresi, M. Aytekin, J. Newman, J. DiDonato, R.A. Dweik Plasma levels of high-density lipoprotein cholesterol and outcomes in pulmonary arterial hypertension Am J Respir Crit Care Med 182 2010 661 668
    • (2010) Am J Respir Crit Care Med , vol.182 , pp. 661-668
    • Heresi, G.A.1    Aytekin, M.2    Newman, J.3    Didonato, J.4    Dweik, R.A.5
  • 68
    • 0036079692 scopus 로고    scopus 로고
    • The SELDI-TOF MS approach to proteomics: Protein profiling and biomarker identification
    • H.J. Issaq, T.D. Veenstra, T.P. Conrads, D. Felschow The SELDI-TOF MS approach to proteomics: protein profiling and biomarker identification Biochem Biophys Res Commun 292 2002 587 592
    • (2002) Biochem Biophys Res Commun , vol.292 , pp. 587-592
    • Issaq, H.J.1    Veenstra, T.D.2    Conrads, T.P.3    Felschow, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.