메뉴 건너뛰기




Volumn 9, Issue 6, 2012, Pages 565-567

Genetic markers for ovarian cancer risk: Are we close to seeing a clinical impact?

Author keywords

genetic variants; genome wide association studies; ovarian cancer; risk prediction

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; CA 125 ANTIGEN; K RAS PROTEIN; ORAL CONTRACEPTIVE AGENT;

EID: 84865528636     PISSN: 17410541     EISSN: 1744828X     Source Type: Journal    
DOI: 10.2217/pme.12.58     Document Type: Review
Times cited : (3)

References (18)
  • 2
    • 79958036419 scopus 로고    scopus 로고
    • Effect of screening on ovarian cancer mortality: The prostate, lung, colorectal and ovarian (PLCO) cancer screening randomized controlled trial
    • Buys SS, Partridge E, Black A et al. Effect of screening on ovarian cancer mortality: The prostate, lung, colorectal and ovarian (PLCO) cancer screening randomized controlled trial. JAMA 305(22), 2295-2303 (2011
    • (2011) JAMA , vol.305 , Issue.22 , pp. 2295-2303
    • Buys, S.S.1    Partridge, E.2    Black, A.3
  • 3
    • 65649129680 scopus 로고    scopus 로고
    • Results from four rounds of ovarian cancer screening in a randomized trial
    • Partridge E, Kreimer AR, Greenlee RT et al. Results from four rounds of ovarian cancer screening in a randomized trial. Obstet. Gynecol. 113(4), 775-782 (2009
    • (2009) Obstet. Gynecol. , vol.113 , Issue.4 , pp. 775-782
    • Partridge, E.1    Kreimer, A.R.2    Greenlee, R.T.3
  • 4
    • 0035057806 scopus 로고    scopus 로고
    • BRCA1 and BRCA2 and the genetics of breast and ovarian cancer
    • Welcsh PL, King MC. BRCA1 and BRCA2 and the genetics of breast and ovarian cancer. Hum. Mol. Genet. 10(7), 705-713 (2001 (Pubitemid 32331579)
    • (2001) Human Molecular Genetics , vol.10 , Issue.7 , pp. 705-713
    • Welcsh, P.L.1    King, M.-C.2
  • 7
    • 77953615401 scopus 로고    scopus 로고
    • The inherited genetics of ovarian and endometrial cancer
    • Gayther SA, Pharoah PD. The inherited genetics of ovarian and endometrial cancer. Curr. Opin. Genet. Dev. 20(3), 231-238 (2010
    • (2010) Curr. Opin. Genet. Dev. , vol.20 , Issue.3 , pp. 231-238
    • Gayther, S.A.1    Pharoah, P.D.2
  • 8
    • 84858853451 scopus 로고    scopus 로고
    • Role of common genetic variants in ovarian cancer susceptibility and outcome: Progress to date from the ovarian cancer association consortium (ocac
    • Bolton KL, Ganda C, Berchuck A, Pharaoh PD, Gayther SA. Role of common genetic variants in ovarian cancer susceptibility and outcome: Progress to date from the Ovarian Cancer Association Consortium (OCAC)J. Intern. Med. 271(4), 366-378 (2012
    • (2012) J. Intern. Med. , vol.271 , Issue.4 , pp. 366-378
    • Bolton, K.L.1    Ganda, C.2    Berchuck, A.3    Pharaoh, P.D.4    Gayther, S.A.5
  • 9
    • 69349102630 scopus 로고    scopus 로고
    • A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2
    • Song H, Ramus SJ, Tyrer J et al. A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2. Nat. Genet. 41(9), 996-1001 (2009
    • (2009) Nat. Genet. , vol.41 , Issue.9 , pp. 996-1001
    • Song, H.1    Ramus, S.J.2    Tyrer, J.3
  • 10
    • 77957571905 scopus 로고    scopus 로고
    • A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24
    • Goode EL, Chenevix-Trench G, Song H et al. A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24. Nat. Genet. 42(10), 874-879 (2010
    • (2010) Nat. Genet. , vol.42 , Issue.10 , pp. 874-879
    • Goode, E.L.1    Chenevix-Trench, G.2    Song, H.3
  • 11
    • 47649099448 scopus 로고    scopus 로고
    • Discriminatory accuracy from single-nucleotide polymorphisms in models to predict breast cancer risk
    • DOI 10.1093/jnci/djn180
    • Gail MH. Discriminatory accuracy from single-nucleotide polymorphisms in models to predict breast cancer risk. J. Natl Cancer Inst. 100(14), 1037-1041 (2008 (Pubitemid 352019794)
    • (2008) Journal of the National Cancer Institute , vol.100 , Issue.14 , pp. 1037-1041
    • Gail, M.H.1
  • 12
    • 79958760337 scopus 로고    scopus 로고
    • Polygenic modeling of genome-wide association studies: An application to prostate and breast cancer
    • Witte JS, Hoffmann TJ. Polygenic modeling of genome-wide association studies: An application to prostate and breast cancer. OMICS 15(6), 393-398 (2011
    • (2011) OMICS , vol.15 , Issue.6 , pp. 393-398
    • Witte, J.S.1    Hoffmann, T.J.2
  • 14
    • 65949107547 scopus 로고    scopus 로고
    • Common genetic variation and human traits
    • Goldstein DB. Common genetic variation and human traits. N. Engl. J. Med. 360(17), 1696-1698 (2009
    • (2009) N. Engl. J. Med. , vol.360 , Issue.17 , pp. 1696-1698
    • Goldstein, D.B.1
  • 15
    • 79960037003 scopus 로고    scopus 로고
    • Genetic variation on 9p22 is associated with abnormal ovarian ultrasound results in the prostate, lung, colorectal, and ovarian cancer screening trial
    • Wentzensen N, Black A, Jacobs K et al. Genetic variation on 9p22 is associated with abnormal ovarian ultrasound results in the prostate, lung, colorectal, and ovarian cancer screening trial. PLoS ONE 6(7), e21731 (2011
    • (2011) Plos One , vol.6 , Issue.7
    • Wentzensen, N.1    Black, A.2    Jacobs, K.3
  • 16
    • 77955749949 scopus 로고    scopus 로고
    • A KRAS-variant in ovarian cancer acts as a genetic marker of cancer risk
    • Ratner E, Lu L, Boeke M et al. A KRAS-variant in ovarian cancer acts as a genetic marker of cancer risk. Cancer Res. 70(16), 6509-6515 (2010
    • (2010) Cancer Res. , vol.70 , Issue.16 , pp. 6509-6515
    • Ratner, E.1    Lu, L.2    Boeke, M.3
  • 17
    • 84856096019 scopus 로고    scopus 로고
    • The KRAS-variant genetic test as a marker of increased risk of ovarian cancer
    • Keane FK, Ratner ES. The KRAS-variant genetic test as a marker of increased risk of ovarian cancer. Rev. Obstet. Gynecol. 3(3), 118-121 (2010
    • (2010) Rev. Obstet. Gynecol. , vol.3 , Issue.3 , pp. 118-121
    • Keane, F.K.1    Ratner, E.S.2
  • 18
    • 79957925584 scopus 로고    scopus 로고
    • The role of KRAS rs61764370 in invasive epithelial ovarian cancer: Implications for clinical testing
    • Pharoah PD, Palmieri RT, Ramus SJ et al. The role of KRAS rs61764370 in invasive epithelial ovarian cancer: Implications for clinical testing. Clin. Cancer Res. 17(11), 3742-3750 (2011).
    • (2011) Clin. Cancer Res. , vol.17 , Issue.11 , pp. 3742-3750
    • Pharoah, P.D.1    Palmieri, R.T.2    Ramus, S.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.