Synthetic biological approaches to natural product biosynthesis

Current Opinion in Biotechnology

Volumn 23, Issue 5, 2012, Pages 736-743

  Winter, Jaclyn M ^a   Tang, Yi ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL APPROACH; BIOSYNTHETIC PATHWAY; BIOSYNTHETIC STRATEGIES; CHEMICAL DIVERSITY; HOST ORGANISM; NATURAL PRODUCTS; NEW CHEMICAL ENTITIES; NEW THERAPEUTIC AGENT; PHARMACEUTICAL COMPOUNDS; SMALL MOLECULES; STRUCTURAL FEATURE; TECHNICAL CHALLENGES;

BIOCHEMISTRY; ENZYMES; METABOLITES;

BIOSYNTHESIS;

AMINOCOUMARIN DERIVATIVE; ARTEMISINIC ACID; ARTEMISININ; AUREOTHIN DERIVATIVE; AVERMECTIN; DORAMECTIN; DOXORUBICIN DERIVATIVE; ECOLIMYCIN C; EPOTHILONE C; EPOTHILONE D; ERYTHROMYCIN C; GLYCOSYLTRANSFERASE; NATURAL PRODUCT; NONRIBOSOMAL PEPTIDE SYNTHETASE; POLYKETIDE SYNTHASE; POLYNIK A; POLYOXIN N; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

AMINO ACID METABOLISM; ANTIBIOTIC BIOSYNTHESIS; BACTERIAL GENOME; BIOCATALYST; BIOSYNTHESIS; COMBINATORIAL CHEMISTRY; DRUG STRUCTURE; ENZYME SPECIFICITY; EPIGENETICS; GENOMICS; HETEROLOGOUS EXPRESSION; METABOLIC ENGINEERING; NONHUMAN; PRIORITY JOURNAL; REVIEW; STREPTOMYCES; SYNTHETIC BIOLOGY;

BACTERIA; BIOLOGICAL AGENTS; BIOSYNTHETIC PATHWAYS; ENZYMES; PROTEIN ENGINEERING; SUBSTRATE SPECIFICITY; SYNTHETIC BIOLOGY;

EID: 84865515585     PISSN: 09581669     EISSN: 18790429     Source Type: Journal    
DOI: 10.1016/j.copbio.2011.12.016     Document Type: Review

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