Cross-validation of input functions obtained by H215O PET imaging of rat heart and a blood flow-through detector

Molecular Imaging and Biology

Volumn 14, Issue 4, 2012, Pages 509-516

  Kudomi, Nobuyuki ^a,b   Sipilä, Hannu ^a   Autio, Anu ^a   Oikonen, Vesa ^a   Liljenbäck, Heidi ^a,c   Tarkia, Miikka ^a   Laivola, Jarno ^a   Johansson, Jarkko ^a   Teräs, Mika ^a   Roivainen, Anne ^a,c  

^a TURKU UNIVERSITY HOSPITAL   (Finland)

^b KAGAWA UNIVERSITY   (Japan)

^c UNIVERSITY OF TURKU   (Finland)

Author keywords

H215O; Input function; PET; Small animal

Indexed keywords

ADENOSINE; WATER O 15;

ANIMAL EXPERIMENT; ARTERIAL BLOOD; ARTICLE; BLOOD FLOW; BRAIN BLOOD FLOW; FEMORAL ARTERY; HEART; HEART LEFT VENTRICLE; HEART MUSCLE; HEART MUSCLE BLOOD FLOW; INTERMETHOD COMPARISON; MALE; NONHUMAN; PHARMACOLOGIC STRESS TESTING; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RADIOACTIVITY; RAT; REPRODUCIBILITY; TEST RETEST RELIABILITY; VALIDATION PROCESS;

ANIMALS; BRAIN; CEREBROVASCULAR CIRCULATION; CORONARY CIRCULATION; HEART; LINEAR MODELS; MALE; OXYGEN RADIOISOTOPES; POSITRON-EMISSION TOMOGRAPHY; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; WATER;

ANIMALIA; RATTUS;

EID: 84865514149     PISSN: 15361632     EISSN: 18602002     Source Type: Journal    
DOI: 10.1007/s11307-011-0511-5     Document Type: Article

References (28)

1. Ploux L, Mastrippolito R (1998) In vivo radiolabel quantification in small-animal models. Nucl Med Biol 25:737-742 (Pubitemid 28557097)
2. Myers R, Hume S, Bloomfield P et al (1999) Radio-imaging in small animals. J Psychopharmacol 13:352-357 (Pubitemid 30055179)
3. Dupont P, Warwick J (2009) Kinetic modelling in small animal imaging with PET. Methods 48:98-103
4. Hoff J (2000) Methods of blood collection in the mouse. Lab Anim (NY) 29:47-53
5. Wu HM, Sui G, Lee CC et al (2007) In vivo quantitation of glucose metabolism in mice using small-animal PET and a microfluidic device. J Nucl Med 48:837-845 (Pubitemid 47604986)
6. Weber B, Burger C, Biro P et al (2002) A femoral arteriovenous shunt facilitates arterial whole blood sampling in animals. Eur J Nucl Med Mol Imaging 29:319-323 (Pubitemid 34253242)
7. Weber B, Späth N, Wyss M et al (2003) Quantitative cerebral blood flow measurements in the rat using a beta-probe and H2 15O. J Cereb Blood Flow Metab 23:1455-1460 (Pubitemid 38018264)
8. Fang YH, Muzic RF Jr (2008) Spillover and partial-volume correction for image-derived input functions for small-animal 18F-FDG PET studies. J Nucl Med 49:606-614 (Pubitemid 351520609)
9. Kudomi N, Bucci M, Oikonen V, et al (2011) Extraction of input function from rat [18F]FDG PET images Mol Imaging Biol (in press)
10. Iida H, Rhodes CG, de Silva R et al (1992) Use of the left ventricular time-activity curve as a noninvasive input function in dynamic oxygen-15-water positron emission tomography. J Nucl Med 33:1669-1677
11. Strijckmans K, Vandecasteela C, Sambre J (1983) Production and quality control of [15O]O2 and [15O]CO2 for medical use. Int J Appl Radiat Isot 36:279-283
12. Sipilä HT, Clark JC, Peltola O et al (2001) An automatic [15O]H2O production system for heart and brain studies. J Labelled Compd Rad 44:S1066-S1068
13. de Jong HW, van Velden FH, Kloet RW et al (2007) Performance evaluation of the ECAT HRRT: an LSO-LYSO double layer high resolution, high sensitivity scanner. Phys Med Biol 52:1505-1526 (Pubitemid 46646401)
14. Sipilä HT, Roivainen A, Kudomi N, et al A Multi-wire proportional counter for measurement of positron-emitting radionuclides during online blood sampling. In: Nuclear Science Symposium Conference Record, NSS'10. IEEE, Knoxville, T.N.
15. Iida H, Higano S, Tomura N et al (1988) Evaluation of regional differences of tracer appearance time in cerebral tissues using [15O] water and dynamic positron emission tomography. J Cereb Blood Flow Metab 8:285-288 (Pubitemid 18079699)
16. Yee SH, Jerabek PA, Fox PT (2005) Non-invasive quantification of cerebral blood flow for rats by microPET imaging of 15O labelled water: the application of a cardiac time-activity curve for the tracer arterial input function. Nucl Med Commun 26:903-911 (Pubitemid 41426553)
17. Iida H, Kanno I, Miura S et al (1986) Error analysis of a quantitative cerebral blood flow measurement using H2 15O autoradiography and positron emission tomography, with respect to the dispersion of the input function. J Cereb Blood Flow Metab 6:536-545 (Pubitemid 17198737)
18. Munk OL, Keiding S, Bass L (2008) A method to estimate dispersion in sampling catheters and to calculate dispersion-free blood time-activity curves. Med Phys 35:3471-3481
19. Pain F, Lanièce P, Mastrippolito R et al (2004) Arterial input function measurement without blood sampling using a beta-microprobe in rats. J Nucl Med 45:1577-1582 (Pubitemid 47618513)
20. Laforest R, Sharp TL, Engelbach JA et al (2005) Measurement of input functions in rodents: challenges and solutions. Nucl Med Biol 32:679-685 (Pubitemid 41502972)
21. Croteau E, Bénard F, Bentourkia M et al (2004) Quantitative myocardial perfusion and coronary reserve in rats with 13N-ammonia and small animal PET: impact of anesthesia and pharmacologic stress agents. J Nucl Med 45:1924-1930 (Pubitemid 47618452)
22. Huang SC, Barrio JR, Yu DC et al (1991) Modelling approach for separating blood timeactivity curves in positron emission tomographic studies. Phys Med Biol 36:749-761
23. Iida H, Jones T, Miura S (1993) Modeling approach to eliminate the need to separate arterial plasma in oxygen-15 inhalation positron emission tomography. J Nucl Med 34:1333-1340 (Pubitemid 23230365)
24. Kudomi N, Hayashi T, Watabe H et al (2009) A physiologic model for recirculation water correction in CMRO2 assessment with 15O2 nhalation PET. J Cereb Blood Flow Metab 29:355-364
25. Nakao Y, Itoh Y, Kuang TY et al (2001) Effects of anesthesia on functional activation of cerebral blood flow and metabolism. Proc Natl Acad Sci USA 98:7593-7598 (Pubitemid 32567993)
26. Moskalenko YuE, Rovainen C, Woolsey TA et al (1995) Combinations of methods for monitoring the microcirculation of the brain. Neurosci Behav Physiol 25:266-272
27. Pain F, Laniece P, Mastrippolito R et al (2000) SIC, an intracerebral radiosensitive probe for in vivo neuropharmacology investigations in small laboratory animals: theoretical considerations and physical characteristics. IEEE Trans Nucl Sci 47:25-32 (Pubitemid 30584685)
28. Kudomi N, Järvisalo MJ, Kiss J et al (2009) Non-invasive estimation of hepatic glucose uptake from [18F]FDG PET images using tissue-derived input functions. Eur J Nucl Med Mol Imaging 36:2014-2026