Low frequency and intensity ultrasound induces apoptosis of brain glioma in rats mediated by caspase-3, Bcl-2, and survivin

Brain Research

Volumn 1473, Issue , 2012, Pages 25-34

  Zhang, Zhen ^a   Chen, Jiang ^a   Chen, Lufeng ^a   Yang, Xianli ^b   Zhong, Hongshan ^a   Qi, Xun ^a   Bi, Yonghua ^a   Xu, Ke ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

^b Langxiang Forestry Staff Hospital   (China)

Author keywords

Apoptotsis; Bcl 2; Caspase 3; Low frequency and intensity ultrasound; Survivin

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CASPASE 3; PROTEIN BCL 2; SURVIVIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL NUCLEUS; CELL PROLIFERATION; CELL STRUCTURE; CELL VIABILITY; CHROMATIN; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GLIOMA; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LOW FREQUENCY INTENSITY ULTRASOUND; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TRANSMISSION ELECTRON MICROSCOPY; TUMOR VOLUME; ULTRASOUND; UPREGULATION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; BRAIN NEOPLASMS; CASPASE 3; DISEASE MODELS, ANIMAL; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GLIOMA; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; MICROSCOPY, ELECTRON, TRANSMISSION; MICROTUBULE-ASSOCIATED PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, WISTAR;

RATTUS;

EID: 84865511420     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2012.06.047     Document Type: Article

References (20)

1. A. Abdollahi, S. Domhan, J.W. Jenne, M. Hallaj, G. Dell'Aqua, M. Mueckenthaler, A. Richter, H. Martin, J. Debus, W. Ansorge, K. Hynynen, and P.E. Huber Apoptosis signals in lymphoblasts induced by focused ultrasound FASEB J. 18 12 2004 1413 1414
2. C.F. Caskey, S.M. Stieger, S. Qin, P.A. Dayton, and K.W. Ferrara Direct observations of ultrasoundmicrobubble contrast agent interaction with the microvessel wall J. Acoust. Soc. Am. 122 2007 1191 1200
3. Z.Y. Chen, K. Liang, and R.X. Qiu Targeted gene delivery in tumor xenografts by the combination of ultrasound-targeted microbubble destruction and polyethylenimine to inhibit survivin gene expression and induce apoptosis J. Exp. Clin. Cancer Res. 29 2010 152
4. Y. Feng, Z. Tian, and M. Wan Bioeffects of low-intensity ultrasound in vitro: apoptosis, protein profile alteration, and potential molecular mechanism J. Ultrasound Med. 29 6 2010 963 974
5. S.A. Grossman, and J.F. Batara Current management of glioblastoma multiforme Semin. Oncol. 31 5 2004 635 644
6. Y. He, Y. Bi, Y. Hua, D. Liu, S. Wen, Q. Wang, M. Li, J. Zhu, T. Lin, D. He, X. Li, Z. Wang, and G. Wei Ultrasound microbubble-mediated delivery of the siRNAs targeting MDR1 reduces drug resistance of yolk sac carcinoma L2 cells J. Exp. Clin. Cancer Res. 30 2011 104
7. G.A. Husseini, M.A. Diaz de la Rosa, E.S. Richardson, D.A. Christensen, and W.G. Pitt The role of cavitation in acoustically activated drug delivery J. Control. Release 107 2005 253 261
8. S. Ibsen, M. Benchimol, D. Simberg, C. Schutt, J. Steiner, and S. Esener Localized activation and cellular effects of ultrasound triggered drug delivery vehicles with encapsulated microbubbles J. Acoust. Soc. Am. 130 4 2011 2503
9. M. Kinoshita, Y. Eguchi, and K. Hynynen Activation of Bak in ultrasound-induced, JNK- and p38-independent apoptosis and its inhibition by Bcl-2 Biochem. Biophys. Res. Commun. 353 2 2007 515 521
10. B. Krasovitski, V. Frenkel, S. Shoham, and E. Kimmel Intramembrane cavitation as a unifying mechanism for ultrasound-induced bioeffects Proc. Natl. Acad. Sci. U.S.A. 108 8 2011 3258 3263
11. P. Palumbo, B. Cinque, G. Miconi, C. La Torre, G. Zoccali, N. Vrentzos, A.R. Vitale, P. Leocata, D. Lombardi, C. Lorenzo, B. D'Angelo, G. Macchiarelli, A. Cimini, M.G. Cifone, and M. Giuliani Biological effects of low frequency high intensity ultrasound application on ex vivo human adipose tissue Int. J. Immunopathol. Pharmacol. 24 2 2011 411 422
12. S.B. Raymond, J. Skoch, K. Hynynen, and B.J. Bacskai Multiphoton imaging of ultrasound/Optison mediated cerebrovascular effects in vivo J. Cereb. Blood Flow Metab. 27 2007 393 403
13. A.G. Sorace, J.M. Warram, H. Umphrey, and K. Hoyt Microbubble-mediated ultrasonic techniques for improved chemotherapeutic delivery in cancer J. Drug. Target. 20 1 2012 43 54
14. Z.M. Tian, M.X. Wan, M.Z. Lu, X.D. Wang, and L. Wan,g The alteration of protein profile of Walker 256 carinosarcoma cells during the apoptotic process induced by ultrasound Ultrasound Med. Biol. 31 1 2005 121 128
15. C.Y. Ting, C.H. Fan, H.L. Liu, C.Y. Huang, H.Y. Hsieh, T.C. Yen, K.C. Wei, and C.K. Yeh Concurrent bloodbrain barrier opening and local drug delivery using drug-carrying microbubbles and focused ultrasound for brain glioma treatment Biomaterials 33 2 2012 704 712
16. L.F. Tirapelli, P.H. Bolini, D.P. Tirapelli, F.M. Peria, A.N. Becker, F.P. Saggioro, and C.G. Carlotti Jr. Caspase-3 and Bcl-2 expression in glioblastoma, An immunohistochemical study Arq. Neuropsiquiatr. 68 4 2010 603 607
17. N. Vykhodtseva, N. McDannold, H. Martin, R.T. Bronson, and K. Hynynen Apoptosis in ultrasound-produced threshold lesions in the rabbit brain Ultrasound Med. Biol. 27 1 2001 111 117
18. J. Wang, Y. Zheng, F. Yang, P. Zhao, and H. Li Survivin small interfering RNA transfected with a microbubble and ultrasound exposure inducing apoptosis in ovarian carcinoma cells Int. J. Gynecol. Cancer 20 4 2010 500 506
19. F. Wu, Z.Y. Shao, B.J. Zhai, C.L. Zhao, and D.M. Shen Ultrasound reverses multidrug resistance in human cancer cells by altering gene expression of ABC transporter proteins and Bax protein Ultrasound Med. Biol. 37 1 2011 151 159
20. Z. Zhang, C. Xia, Y. Xue, and Y. Liu Synergistic effect of low-frequency ultrasound and low-dose bradykinin on increasing permeability of the bloodtumor barrier by opening tight junction J. Neurosci. Res. 87 10 2009 2282 2289