Optical coherence tomography findings of very late stent thrombosis after drug-eluting stent implantation

International Journal of Cardiovascular Imaging

Volumn 28, Issue 4, 2012, Pages 715-723

  Ko, Young Guk ^a   Kim, Dong Min ^a   Cho, Jin Man ^b   Choi, So Yeon ^c   Yoon, Jung Han ^d   Kim, Jung Sun ^a   Kim, Byeong Keuk ^a   Choi, Donghoon ^a   Jang, Yangsoo ^a,e   Hong, Myeong Ki ^a,e  

^a Yonsei University College of Medicine   (South Korea)

^b Kyung Hee University College of Medicine   (South Korea)

^c Ajou University School of Medicine   (South Korea)

^d Wonju Severance Christian Hospital   (South Korea)

^e Yonsei University College of Medicine   (South Korea)

Author keywords

Optical coherence tomography; Stent; Thrombosis

Indexed keywords

CYPHER; ENDEAVOR SPLINT; EVEROLIMUS; PACLITAXEL; PROMUS; RAPAMYCIN; TAXUS LIBERTE; UNCLASSIFIED DRUG; ZOTAROLIMUS;

ACUTE HEART INFARCTION; ADULT; ANGIOCARDIOGRAPHY; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DRUG ELUTING STENT; FEMALE; HUMAN; LIPID LADEN NEOINTIMA; MALE; NEOINTIMA; NEOINTIMAL HYPERPLASIA; OPTICAL COHERENCE TOMOGRAPHY; STENOSIS; STENT STRUT; STENT THROMBOSIS; TREATMENT OUTCOME;

ADULT; AGED; ANGIOPLASTY, BALLOON, CORONARY; CARDIOVASCULAR AGENTS; CHI-SQUARE DISTRIBUTION; CORONARY ANGIOGRAPHY; CORONARY ARTERY DISEASE; CORONARY THROMBOSIS; CORONARY VESSELS; DRUG-ELUTING STENTS; FEMALE; HUMANS; HYPERPLASIA; LIPID METABOLISM; MALE; MIDDLE AGED; NEOINTIMA; PACLITAXEL; PREDICTIVE VALUE OF TESTS; PROSTHESIS DESIGN; REPUBLIC OF KOREA; RISK ASSESSMENT; RISK FACTORS; SIROLIMUS; TIME FACTORS; TOMOGRAPHY, OPTICAL COHERENCE; TREATMENT OUTCOME;

EID: 84865508690     PISSN: 15695794     EISSN: 15730743     Source Type: Journal    
DOI: 10.1007/s10554-011-9905-3     Document Type: Article

References (33)

1. Moses JW, Leon MB, Popma JJ, Fitzgerald PJ, Holmes DR, O'Shaughnessy C, Caputo RP, Kereiakes DJ, Williams DO, Teirstein PS, Jaeger JL, Kuntz RE (2003) Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery. N Engl J Med 349(14):1315-1323 (Pubitemid 37186209)
2. Stone GW, Ellis SG, Cox DA, Hermiller J, O'Shaughnessy C, Mann JT, Turco M, Caputo R, Bergin P, Greenberg J, Popma JJ, Russell ME (2004) A polymer-based, paclitaxel-eluting stent in patients with coronary artery disease. N Engl J Med 350(3):221-231 (Pubitemid 38067635)
3. Camenzind E, Steg PG, Wijns W (2007) Stent thrombosis late after implantation of first-generation drug-eluting stents: a cause for concern. Circulation 115(11):1440-1455 (Pubitemid 46648381)
4. Nordmann AJ, Briel M, Bucher HC (2006) Mortality in randomized controlled trials comparing drug-eluting versus bare metal stents in coronary artery disease: a meta-analysis. Euro Heart J 27(23):2784-2814 (Pubitemid 44871464)
5. Finn AV, Joner M, Nakazawa G, Kolodgie F, Newell J, John MC, Gold HK, Virmani R (2007) Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization. Circulation 115(18): 2435-2441 (Pubitemid 46717966)
6. Joner M, Finn AV, Farb A, Mont EK, Kolodgie FD, Ladich E, Kutys R, Skorija K, Gold HK, Virmani R (2006) Pathology of drug-eluting stents in humans: delayed healing and late thrombotic risk. J Am Coll Cardiol 48(1): 193-202 (Pubitemid 43929240)
7. Farb A, Burke AP, Kolodgie FD, Virmani R (2003) Pathological mechanisms of fatal late coronary stent thrombosis in humans. Circulation 108(14):1701-1706 (Pubitemid 37243657)
8. Bezerra HG, Costa MA, Guagliumi G, Rollins AM, Simon DI (2009) Intracoronary optical coherence tomography: a comprehensive review clinical and research applications. JACC Cardiovasc Interv 2(11):1035-1046
9. Hou J, Qi H, Zhang M, Ma L, Liu H, Han Z, Meng L, Yang S, Zhang S, Yu B, Jang IK (2010) Development of lipidrich plaque inside bare metal stent: possible mechanism of late stent thrombosis? an optical coherence tomography study. Heart 96:1187-1190
10. Takano M, Yamamoto M, Inami S, Murakami D, Ohba T, Seino Y, Mizuno K (2009) Appearance of lipid-laden intima and neovascularization after implantation of baremetal stents extended late-phase observation by intracoronary optical coherence tomography. J Am Coll Cardiol 55:26-32
11. Lee CW, Kang SJ, Park DW, Lee SH, Kim YH, Kim JJ, Park SW, Mintz GS, Park SJ (2010) Intravascular ultrasound findings in patients with very late stent thrombosis after either drug-eluting or bare-metal stent implantation. J Am Coll Cardiol 55:1936-1942
12. Cutlip DE, Windecker S, Mehran R, Boam A, Cohen DJ, van Es GA, Steg PG, Morel MA, Mauri L, Vranckx P, McFadden E, Lansky A, Hamon M, Krucoff MW, Serruys PW (2007) Clinical end points in coronary stent trials: a case for standardized definitions. Circulation 115:2344-2351 (Pubitemid 46685903)
13. Kim U, Kim JS, Lee JM, Son JW, Kim J, Ko YG, Choi D, Jang Y (2010) The initial extent of malapposition in ST-elevation myocardial infarction treated with drug-eluting stent: the usefulness of optical coherence tomography. Yonsei Med J 51:332-338
14. Kim JS, Hong MK, Fan C, Kim TH, Shim JM, Park SM, Ko YG, Choi D, Jang Y (2010) Intracoronary thrombus formation after drug-eluting stents implantation: Optical coherence tomographic study. Am Heart J 159:278-283
15. Takano M, Inami S, Jang IK, Yamamoto M, Murakami D, Seimiya K, Ohba T, Mizuno K (2007) Evaluation by optical coherence tomography of neointimal coverage of sirolimus-eluting stent 3 months after implantation. Am J Cardiol 99:1033-1038 (Pubitemid 46560470)
16. Tanigawa J, Barlis P, Dimopoulos K, Dalby M, Moore P, Di Mario C (2008) The influence of strut thickness and cell design on immediate apposition of drug-eluting stents assessed by optical coherence tomography. Int J Cardiol 134:180-188
17. Kume T, Akasaka T, Kawamoto T, Ogasawara Y, Watanabe N, Toyota E, Neishi Y, Sukmawan R, Sadahira Y, Yoshida K (2006) Assessment of coronary arterial thrombus by optical coherence tomography. Am J Cardiol 97: 1713-1717 (Pubitemid 43817856)
18. Kwon SW, Kim BK, Kim TH, Kim JS, Ko YG, Choi D, Jang Y, Hong MK (2011) Qualitative assessment of neointimal tissue after drug-eluting stent implantation: comparison between follow-up optical coherence tomography and intravascular ultrasound. Am Heart J 161:367-372
19. Stettler C, Wandel S, Allemann S, Kastrati A, Morice MC, Schomig A, Pfisterer ME, Stone GW, Leon MB, de Lezo JS, Goy JJ, Park SJ, Sabate M, Suttorp MJ, Kelbaek H, Spaulding C, Menichelli M, Vermeersch P, Dirksen MT, Cervinka P, Petronio AS, Nordmann AJ, Diem P, Meier B, Zwahlen M, Reichenbach S, Trelle S, Windecker S, Juni P (2007) Outcomes associated with drug-eluting and baremetal stents: a collaborative network meta-analysis. Lancet 370:937-948 (Pubitemid 47393576)
20. Spaulding C, Daemen J, Boersma E, Cutlip DE, Serruys PW (2007) A pooled analysis of data comparing sirolimuseluting stents with bare-metal stents. N Engl J Med 356: 989-997 (Pubitemid 46376799)
21. Stone GW, Moses JW, Ellis SG, Schofer J, Dawkins KD, Morice MC, Colombo A, Schampaert E, Grube E, Kirtane AJ, Cutlip DE, Fahy M, Pocock SJ, Mehran R, Leon MB (2007) Safety and efficacy of sirolimus- and paclitaxel-eluting coronary stents. N Engl J Med 356:998-1008 (Pubitemid 46376800)
22. Serruys PW, Daemen J (2007) Are drug-eluting stents associated with a higher rate of late thrombosis than bare metal stents? Late stent thrombosis: a nuisance in both bare metal and drug-eluting stents. Circulation 115:1433-1439
23. Doyle B, Rihal CS, O'Sullivan CJ, Lennon RJ, Wiste HJ, Bell M, Bresnahan J, Holmes DR Jr (2007) Outcomes of stent thrombosis and restenosis during extended follow-up of patients treated with bare-metal coronary stents. Circulation 116:2391-2398 (Pubitemid 350145074)
24. Finn AV, Nakazawa G, Joner M, Kolodgie FD, Mont EK, Gold HK, Virmani R (2007) Vascular responses to drug eluting stents: importance of delayed healing. Arterioscler Thromb Vasc Biol 27:1500-1510 (Pubitemid 46986103)
25. Cook S, Wenaweser P, Togni M, Billinger M, Morger C, Seiler C, Vogel R, Hess O, Meier B, Windecker S (2007) Incomplete stent apposition and very late stent thrombosis after drug-eluting stent implantation. Circulation 115: 2426-2434 (Pubitemid 46717965)
26. Hassan AK, Bergheanu SC, Stijnen T, van der Hoeven BL, Snoep JD, Plevier JW, Schalij MJ, Wouter Jukema J (2010) Late stent malapposition risk is higher after drug-eluting stent compared with bare-metal stent implantation and associates with late stent thrombosis. Eur Heart J 31: 1172-1180
27. Cook S, Ladich E, Nakazawa G, Eshtehardi P, Neidhart M, Vogel R, Togni M, Wenaweser P, Billinger M, Seiler C, Gay S, Meier B, Pichler WJ, Juni P, Virmani R, Windecker S (2009) Correlation of intravascular ultrasound findings with histopathological analysis of thrombus aspirates in patients with very late drug-eluting stent thrombosis. Circulation 120:391-399
28. Matsumoto D, Shite J, Shinke T, Otake H, Tanino Y, Ogasawara D, Sawada T, Paredes OL, Hirata K, Yokoyama M (2007) Neointimal coverage of sirolimus-eluting stents at 6 month follow-up: evaluated by optical coherence tomography. Eur Heart J 28:961-967 (Pubitemid 47343895)
29. Hasegawa K, Tamai H, Kyo E, Kosuga K, Ikeguchi S, Hata T, Okada M, Fujita S, Tsuji T, Takeda S, Fukuhara R, Kikuta Y, Motohara S, Ono K, Takeuchi E (2006) Histopathological findings of new in-stent lesions developed beyond 5 years. Catheter Cardiovasc Interv 68:554-558 (Pubitemid 44546049)
30. Nakazawa G, Vorpahl M, Finn AV, Narula J, Virmani R (2009) One step forward and two steps back with drug-eluting-stents: from preventing restenosis to causing late thrombosis and nouveau atherosclerosis. JACC: Cardiovascular Imaging 2:625-628
31. Nakazawa G, Otsuka F, Nakano M, Vorpahl M, Yazdani SK, Ladich E, Kolodgie FD, Finn AV, Virmani R (2011) The pathology of neoatherosclerosis in human coronary implants bare-metal and drug-eluting stents. J Am Coll Cardiol 57(11):1314-1322
32. Ross R (1999) Atherosclerosis-an inflammatory disease. N Engl J Med 340:115-126
33. Prati F, Regar E, Mintz GS, Arbustini E, Di Mario C, Jang IK, Akasaka T, Costa M, Guagliumi G, Grube E, Ozaki Y, Pinto F, Serruys PW (2010) Expert review document on methodology, terminology, and clinical applications of optical coherence tomography: physical principles, methodology of image acquisition, and clinical application for assessment of coronary arteries and atherosclerosis. Euro Heart J 31(4):401-415