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Volumn 3, Issue 8, 2012, Pages 997-1004

Mesenchymal stem cells in drug/gene delivery: Implications for cell therapy

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; BRAIN DERIVED NEUROTROPHIC FACTOR; CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CXCR4; CYTOSINE DEAMINASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; EPHRIN RECEPTOR A2; ERYTHROPOIETIN; GAMMA INTERFERON; GLUCAGON LIKE PEPTIDE 1; INTERLEUKIN 2; MONOCYTE CHEMOTACTIC PROTEIN 1 INHIBITOR; RINDOPEPIMUT; SCATTER FACTOR; SOMATOMEDIN C; STROMAL CELL DERIVED FACTOR 1; SURVIVIN; THYMIDINE KINASE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; TYROSINE 3 MONOOXYGENASE; URACIL PHOSPHORIBOSYLTRANSFERASE; VASCULOTROPIN;

EID: 84865492634     PISSN: 20415990     EISSN: 20416008     Source Type: Journal    
DOI: 10.4155/tde.12.69     Document Type: Article
Times cited : (60)

References (63)
  • 2
    • 79955137985 scopus 로고    scopus 로고
    • Mesenchymal stem cell therapy for knee osteoarthritis. Preliminary report of four patients
    • Davatchi F, Abdollahi BS, Mohyeddin M, Shahram F, Nikbin B. Mesenchymal stem cell therapy for knee osteoarthritis. Preliminary report of four patients. Int. J. Rheum. Dis. 14(2), 211-215 (2011).
    • (2011) Int. J. Rheum. Dis. , vol.14 , Issue.2 , pp. 211-215
    • Davatchi, F.1    Abdollahi, B.S.2    Mohyeddin, M.3    Shahram, F.4    Nikbin, B.5
  • 3
    • 80053324854 scopus 로고    scopus 로고
    • Intervertebral disc repair by autologous mesenchymal bone marrow cells: A pilot study
    • Orozco L, Soler R, Morera C, Alberca M, Sanchez A, Garcia-Sancho J. Intervertebral disc repair by autologous mesenchymal bone marrow cells: a pilot study. Transplantation 92(7), 822-828 (2011).
    • (2011) Transplantation , vol.92 , Issue.7 , pp. 822-828
    • Orozco, L.1    Soler, R.2    Morera, C.3    Alberca, M.4    Sanchez, A.5    Garcia-Sancho, J.6
  • 4
    • 79251549505 scopus 로고    scopus 로고
    • Safety of autologous bone marrow-derived mesenchymal stem cell transplantation for cartilage repair in 41 patients with 45 joints followed for up to 11 years and 5 months
    • Wakitani S, Okabe T, Horibe S et al. Safety of autologous bone marrow-derived mesenchymal stem cell transplantation for cartilage repair in 41 patients with 45 joints followed for up to 11 years and 5 months. J. Tissue Eng. Regen. Med. 5(2), 146-150 (2011).
    • (2011) J. Tissue Eng. Regen. Med. , vol.5 , Issue.2 , pp. 146-150
    • Wakitani, S.1    Okabe, T.2    Horibe, S.3
  • 5
    • 36248984369 scopus 로고    scopus 로고
    • An interdisciplinary approach and characterization of neuronal cells transdifferentiated from human mesenchymal stem cells
    • DOI 10.1089/scd.2007.0011
    • Greco SJ, Zhou C, Ye JH, Rameshwar P. An interdisciplinary approach and characterization of neuronal cells transdifferentiated from human mesenchymal stem cells. Stem Cells Dev. 16(5), 811-826 (2007). (Pubitemid 350125224)
    • (2007) Stem Cells and Development , vol.16 , Issue.5 , pp. 811-826
    • Greco, S.J.1    Zhou, C.2    Ye, J.-H.3    Rameshwar, P.4
  • 6
    • 84873612804 scopus 로고    scopus 로고
    • Mesenchymal stem cell therapy prevents IFTA in a rat kidney allograft model
    • Epub ahead of print
    • Franquesa M, Herrero E, Torras J et al. Mesenchymal stem cell therapy prevents IFTA in a rat kidney allograft model. Stem Cells Dev. (2012) (Epub ahead of print).
    • (2012) Stem Cells Dev.
    • Franquesa, M.1    Herrero, E.2    Torras, J.3
  • 7
    • 84855873979 scopus 로고    scopus 로고
    • Mesenchymal stem cell therapy on murine model of nonalcoholic steatohepatitis
    • Sakai Y, Kaneko S. Mesenchymal stem cell therapy on murine model of nonalcoholic steatohepatitis. Methods Mol. Biol. 826, 217-223 (2012).
    • (2012) Methods Mol. Biol. , vol.826 , pp. 217-223
    • Sakai, Y.1    Kaneko, S.2
  • 8
    • 77957921692 scopus 로고    scopus 로고
    • Mesenchymal stem cell therapy regenerates the native bone-tendon junction after surgical repair in a degenerative rat model
    • Nourissat G, Diop A, Maurel N et al. Mesenchymal stem cell therapy regenerates the native bone-tendon junction after surgical repair in a degenerative rat model. PLoS ONE 5(8), e12248 (2010).
    • (2010) PLoS ONE , vol.5 , Issue.8
    • Nourissat, G.1    Diop, A.2    Maurel, N.3
  • 9
    • 36248974720 scopus 로고    scopus 로고
    • Injectable mesenchymal stem cell therapy for large cartilage defects - A porcine model
    • DOI 10.1634/stemcells.2006-0311
    • Lee KB, Hui JH, Song IC, Ardany L, Lee EH. Injectable mesenchymal stem cell therapy for large cartilage defects - a porcine model. Stem Cells 25(11), 2964-2971 (2007). (Pubitemid 350127882)
    • (2007) Stem Cells , vol.25 , Issue.11 , pp. 2964-2971
    • Lee, K.B.L.1    Hui, J.H.P.2    Im, C.S.3    Ardany, L.4    Eng, H.L.5
  • 11
    • 35948991433 scopus 로고    scopus 로고
    • Cell guidance in tissue engineering: SDF-1 mediates site-directed homing of mesenchymal stem cells within three-dimensional polycaprolactone scaffolds
    • DOI 10.1089/ten.2006.0438
    • Schantz JT, Chim H, Whiteman M. Cell guidance in tissue engineering: SDF-1 mediates site-directed homing of mesenchymal stem cells within three-dimensional polycaprolactone scaffolds. Tissue Eng. 13(11), 2615-2624 (2007). (Pubitemid 350076752)
    • (2007) Tissue Engineering , vol.13 , Issue.11 , pp. 2615-2624
    • Schantz, J.-T.1    Chim, H.2    Whiteman, M.3
  • 12
    • 2342482526 scopus 로고    scopus 로고
    • Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells
    • DOI 10.1016/S0140-6736(04)16104-7, PII S0140673604161047
    • Le Blanc K, Rasmusson I, Sundberg B et al. Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells. Lancet 363(9419), 1439-1441 (2004). (Pubitemid 38586721)
    • (2004) Lancet , vol.363 , Issue.9419 , pp. 1439-1441
    • Le Blanc, K.1    Rasmusson, I.2    Sundberg, B.3    Gotherstrom, C.4    Hassan, M.5    Uzunel, M.6    Ringden, O.7
  • 15
    • 79959932280 scopus 로고    scopus 로고
    • Mesenchymal stem cells expanded in vitro with human serum for the treatment of acute and chronic graft-versus-host disease: Results of a Phase I/II clinical trial
    • Perez-Simon JA, Lopez-Villar O, Andreu EJ et al. Mesenchymal stem cells expanded in vitro with human serum for the treatment of acute and chronic graft-versus-host disease: results of a Phase I/II clinical trial. Haematologica 96(7), 1072-1076 (2011).
    • (2011) Haematologica , vol.96 , Issue.7 , pp. 1072-1076
    • Perez-Simon, J.A.1    Lopez-Villar, O.2    Andreu, E.J.3
  • 16
    • 77749289235 scopus 로고    scopus 로고
    • Single intra-arterial injection of mesenchymal stromal cells for treatment of steroid-refractory acute graft-versus-host disease: A pilot study
    • Arima N, Nakamura F, Fukunaga A et al. Single intra-arterial injection of mesenchymal stromal cells for treatment of steroid-refractory acute graft-versus-host disease: a pilot study. Cytotherapy 12(2), 265-268 (2010).
    • (2010) Cytotherapy , vol.12 , Issue.2 , pp. 265-268
    • Arima, N.1    Nakamura, F.2    Fukunaga, A.3
  • 17
    • 79952084861 scopus 로고    scopus 로고
    • The mesenchymal stem cells in multiple sclerosis (MSCIMS) trial protocol and baseline cohort characteristics: An open-label pre-test: Post-test study with blinded outcome assessments
    • Connick P, Kolappan M, Patani R et al. The mesenchymal stem cells in multiple sclerosis (MSCIMS) trial protocol and baseline cohort characteristics: an open-label pre-test: post-test study with blinded outcome assessments. Trials 12, 62 (2011).
    • (2011) Trials , vol.12 , pp. 62
    • Connick, P.1    Kolappan, M.2    Patani, R.3
  • 18
    • 77956651196 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cell transplantation in patients with multiple sclerosis: A pilot study
    • Yamout B, Hourani R, Salti H et al. Bone marrow mesenchymal stem cell transplantation in patients with multiple sclerosis: a pilot study. J. Neuroimmunol. 227(1-2), 185-189 (2010).
    • (2010) J. Neuroimmunol. , vol.227 , Issue.1-2 , pp. 185-189
    • Yamout, B.1    Hourani, R.2    Salti, H.3
  • 19
    • 0141886188 scopus 로고    scopus 로고
    • Veto-like activity of mesenchymal stem cells: Functional discrimination between cellular responses to alloantigens and recall antigens
    • Potian JA, Aviv H, Ponzio NM, Harrison JS, Rameshwar P. Veto-like activity of mesenchymal stem cells: functional discrimination between cellular responses to alloantigens and recall antigens. J. Immunol. 171(7), 3426-3434 (2003). One of the pioneering studies to define the immune properties of mesenchymal stem cells (MSCs). (Pubitemid 37254543)
    • (2003) Journal of Immunology , vol.171 , Issue.7 , pp. 3426-3434
    • Potian, J.A.1    Aviv, H.2    Ponzio, N.M.3    Harrison, J.S.4    Rameshwar, P.5
  • 20
    • 33745076513 scopus 로고    scopus 로고
    • Antigen-presenting property of mesenchymal stem cells occurs during a narrow window at low levels of interferon
    • DOI 10.1182/blood-2006-01-0057
    • Chan JL, Tang KC, Patel AP et al. Antigenpresenting property of mesenchymal stem cells occurs during a narrow window at low levels of interferon-gamma. Blood 107(12), 4817-4824 (2006). (Pubitemid 43882633)
    • (2006) Blood , vol.107 , Issue.12 , pp. 4817-4824
    • Chan, J.L.1    Tang, K.C.2    Patel, A.P.3    Bonilla, L.M.4    Pierobon, N.5    Ponzio, N.M.6    Rameshwar, P.7
  • 21
    • 79958825416 scopus 로고    scopus 로고
    • Safety of intravenous infusion of human adipose tissue-derived mesenchymal stem cells in animals and humans
    • Demonstrates the safety and tolerability profile of human MSCs in vivo
    • Ra JC, Shin IS, Kim SH et al. Safety of intravenous infusion of human adipose tissue-derived mesenchymal stem cells in animals and humans. Stem Cells Dev. 20(8), 1297-1308 (2011). Demonstrates the safety and tolerability profile of human MSCs in vivo.
    • (2011) Stem Cells Dev. , vol.20 , Issue.8 , pp. 1297-1308
    • Ra, J.C.1    Shin, I.S.2    Kim, S.H.3
  • 22
    • 30544438742 scopus 로고    scopus 로고
    • Outgrowth of a transformed cell population derived from normal human BM mesenchymal stem cell culture
    • DOI 10.1080/14653240500363216, PII N7748614010732
    • Wang Y, Huso DL, Harrington J et al. Outgrowth of a transformed cell population derived from normal human BM mesenchymal stem cell culture. Cytotherapy 7(6), 509-519 (2005). (Pubitemid 43078081)
    • (2005) Cytotherapy , vol.7 , Issue.6 , pp. 509-519
    • Wang, Y.1    Huso, D.I.2    Harrington, J.3    Kellner, J.4    Jeong, D.K.5    Turney, J.6    McNiece, I.K.7
  • 23
    • 79955984136 scopus 로고    scopus 로고
    • Neoplastic transformation by TERT in FGF-2-expanded human mesenchymal stem cells
    • Yamaoka E, Hiyama E, Sotomaru Y et al. Neoplastic transformation by TERT in FGF-2-expanded human mesenchymal stem cells. Int. J. Oncol. 39(1), 5-11 (2011).
    • (2011) Int. J. Oncol. , vol.39 , Issue.1 , pp. 5-11
    • Yamaoka, E.1    Hiyama, E.2    Sotomaru, Y.3
  • 24
    • 77957375466 scopus 로고    scopus 로고
    • Mesenchymal stem cells modified with a single-chain antibody against EGFRvIII successfully inhibit the growth of human xenograft malignant glioma
    • Balyasnikova IV, Ferguson SD, Sengupta S, Han Y, Lesniak MS. Mesenchymal stem cells modified with a single-chain antibody against EGFRvIII successfully inhibit the growth of human xenograft malignant glioma. PLoS ONE 5(3), e9750 (2010).
    • (2010) PLoS ONE , vol.5 , Issue.3
    • Balyasnikova, I.V.1    Ferguson, S.D.2    Sengupta, S.3    Han, Y.4    Lesniak, M.S.5
  • 25
    • 79951602634 scopus 로고    scopus 로고
    • Therapeutic efficacy and safety of TRAIL-producing human adipose tissue-derived mesenchymal stem cells against experimental brainstem glioma
    • Study exemplifying the use of engineered MSCs as cytotoxic agents
    • Choi SA, Hwang SK, Wang KC et al. Therapeutic efficacy and safety of TRAIL-producing human adipose tissue-derived mesenchymal stem cells against experimental brainstem glioma. Neuro. Oncol. 13(1), 61-69 (2011). Study exemplifying the use of engineered MSCs as cytotoxic agents.
    • (2011) Neuro. Oncol. , vol.13 , Issue.1 , pp. 61-69
    • Choi, S.A.1    Hwang, S.K.2    Wang, K.C.3
  • 26
    • 78651066526 scopus 로고    scopus 로고
    • Irradiation enhances the tumor tropism and therapeutic potential of tumor necrosis factor-related apoptosis-inducing ligand-secreting human umbilical cord blood-derived mesenchymal stem cells in glioma therapy
    • Kim SM, Oh JH, Park SA et al. Irradiation enhances the tumor tropism and therapeutic potential of tumor necrosis factor-related apoptosis-inducing ligand-secreting human umbilical cord blood-derived mesenchymal stem cells in glioma therapy. Stem Cells 28(12), 2217-2228 (2010).
    • (2010) Stem Cells , vol.28 , Issue.12 , pp. 2217-2228
    • Kim, S.M.1    Oh, J.H.2    Park, S.A.3
  • 28
    • 80053976962 scopus 로고    scopus 로고
    • Molecular targeting of malignant glioma cells with an EphA2-specific immunotoxin delivered by human bone marrow-derived mesenchymal stem cells
    • Sun XL, Xu ZM, Ke YQ et al. Molecular targeting of malignant glioma cells with an EphA2-specific immunotoxin delivered by human bone marrow-derived mesenchymal stem cells. Cancer Lett. 312(2), 168-177 (2011).
    • (2011) Cancer Lett. , vol.312 , Issue.2 , pp. 168-177
    • Sun, X.L.1    Xu, Z.M.2    Ke, Y.Q.3
  • 29
    • 83755173709 scopus 로고    scopus 로고
    • Human umbilical blood mononuclear cell-derived mesenchymal stem cells serve as interleukin-21 gene delivery vehicles for epithelial ovarian cancer therapy in nude mice
    • Hu W, Wang J, He X et al. Human umbilical blood mononuclear cell-derived mesenchymal stem cells serve as interleukin-21 gene delivery vehicles for epithelial ovarian cancer therapy in nude mice. Biotechnol. Appl. Biochem. 58(6), 397-404 (2011).
    • (2011) Biotechnol. Appl. Biochem. , vol.58 , Issue.6 , pp. 397-404
    • Hu, W.1    Wang, J.2    He, X.3
  • 30
    • 78650836835 scopus 로고    scopus 로고
    • CXCR4-transfected human umbilical cord bloodderived mesenchymal stem cells exhibit enhanced migratory capacity toward gliomas
    • Park SA, Ryu CH, Kim SM et al. CXCR4-transfected human umbilical cord bloodderived mesenchymal stem cells exhibit enhanced migratory capacity toward gliomas. Int. J. Oncol. 38(1), 97-103 (2011).
    • (2011) Int. J. Oncol. , vol.38 , Issue.1 , pp. 97-103
    • Park, S.A.1    Ryu, C.H.2    Kim, S.M.3
  • 31
    • 83755196419 scopus 로고    scopus 로고
    • Mesenchymal stromal cells primed with paclitaxel provide a new approach for cancer therapy
    • Pessina A, Bonomi A, Cocce V et al. Mesenchymal stromal cells primed with paclitaxel provide a new approach for cancer therapy. PLoS ONE 6(12), e28321 (2011).
    • (2011) PLoS ONE , vol.6 , Issue.12
    • Pessina, A.1    Bonomi, A.2    Cocce, V.3
  • 32
    • 84860783872 scopus 로고    scopus 로고
    • Vitamin D (3)-Inducible Mesenchymal stem cell-based delivery of conditionally replicating adenoviruses effectively targets renal cell carcinoma and inhibits tumor growth
    • Hsiao WC, Sung SY, Liao CH, Wu HC, Hsieh CL. Vitamin D (3)-Inducible Mesenchymal stem cell-based delivery of conditionally replicating adenoviruses effectively targets renal cell carcinoma and inhibits tumor growth. Mol. Pharm. 9(5), 1396-408 (2012).
    • (2012) Mol. Pharm. , vol.9 , Issue.5 , pp. 1396-1408
    • Hsiao, W.C.1    Sung, S.Y.2    Liao, C.H.3    Wu, H.C.4    Hsieh, C.L.5
  • 33
    • 80053536433 scopus 로고    scopus 로고
    • Human adipose tissue-derived mesenchymal stem cells: Characteristics and therapeutic potential as cellular vehicles for prodrug gene therapy against brainstem gliomas
    • Study exemplifies how MSCs engineered with specialized enzymes could be utilized as a vehicle for targeted delivery of a toxic drug to a region of interest following peripheral administration of a prodrug
    • Choi SA, Lee JY, Wang KC et al. Human adipose tissue-derived mesenchymal stem cells: characteristics and therapeutic potential as cellular vehicles for prodrug gene therapy against brainstem gliomas. Eur. J. Cancer 48(1), 129-137 (2012). Study exemplifies how MSCs engineered with specialized enzymes could be utilized as a vehicle for targeted delivery of a toxic drug to a region of interest following peripheral administration of a prodrug.
    • (2012) Eur. J. Cancer , vol.48 , Issue.1 , pp. 129-137
    • Choi, S.A.1    Lee, J.Y.2    Wang, K.C.3
  • 34
    • 34447132890 scopus 로고    scopus 로고
    • Adipose tissue-derived human mesenchymal stem cells mediated prodrug cancer gene therapy
    • DOI 10.1158/0008-5472.CAN-06-4024
    • Kucerova L, Altanerova V, Matuskova M, Tyciakova S, Altaner C. Adipose tissuederived human mesenchymal stem cells mediated prodrug cancer gene therapy. Cancer Res. 67(13), 6304-6313 (2007). (Pubitemid 47037513)
    • (2007) Cancer Research , vol.67 , Issue.13 , pp. 6304-6313
    • Kucerova, L.1    Altanerova, V.2    Matuskova, M.3    Tyciakova, S.4    Altaner, C.5
  • 35
    • 79954490385 scopus 로고    scopus 로고
    • Thymidine kinase gene modified bone marrow mesenchymal stem cells as vehicles for antitumor therapy
    • Song C, Xiang J, Tang J et al. Thymidine kinase gene modified bone marrow mesenchymal stem cells as vehicles for antitumor therapy. Hum. Gene Ther. 22(4), 439-449 (2011).
    • (2011) Hum. Gene Ther. , vol.22 , Issue.4 , pp. 439-449
    • Song, C.1    Xiang, J.2    Tang, J.3
  • 36
    • 74149088471 scopus 로고    scopus 로고
    • Adipose tissue-derived mesenchymal stem cells expressing prodrug-converting enzyme inhibit human prostate tumor growth
    • Cavarretta IT, Altanerova V, Matuskova M, Kucerova L, Culig Z, Altaner C. Adipose tissue-derived mesenchymal stem cells expressing prodrug-converting enzyme inhibit human prostate tumor growth. Mol. Ther. 18(1), 223-231 (2010).
    • (2010) Mol. Ther. , vol.18 , Issue.1 , pp. 223-231
    • Cavarretta, I.T.1    Altanerova, V.2    Matuskova, M.3    Kucerova, L.4    Culig, Z.5    Altaner, C.6
  • 37
    • 77954084666 scopus 로고    scopus 로고
    • Mesenchymal stromal cells alone or expressing interferon-beta suppress pancreatic tumors in vivo, an effect countered by anti-inflammatory treatment
    • Kidd S, Caldwell L, Dietrich M et al. Mesenchymal stromal cells alone or expressing interferon-beta suppress pancreatic tumors in vivo, an effect countered by anti-inflammatory treatment. Cytotherapy 12(5), 615-625 (2010).
    • (2010) Cytotherapy , vol.12 , Issue.5 , pp. 615-625
    • Kidd, S.1    Caldwell, L.2    Dietrich, M.3
  • 38
    • 56249091888 scopus 로고    scopus 로고
    • Mesenchymal stem cells expressing TRAIL lead to tumour growth inhibition in an experimental lung cancer model
    • Mohr A, Lyons M, Deedigan L et al. Mesenchymal stem cells expressing TRAIL lead to tumour growth inhibition in an experimental lung cancer model. J. Cell. Mol. Med. 12(6 B), 2628-2643 (2008).
    • (2008) J. Cell. Mol. Med. , vol.12 , Issue.6 B , pp. 2628-2643
    • Mohr, A.1    Lyons, M.2    Deedigan, L.3
  • 39
    • 33749242422 scopus 로고    scopus 로고
    • In vitro effect of adenovirus-mediated human Gamma Interferon gene transfer into human mesenchymal stem cells for chronic myelogenous leukemia
    • DOI 10.1002/hon.779
    • Li X, Lu Y, Huang W et al. In vitro effect of adenovirus-mediated human gamma interferon gene transfer into human mesenchymal stem cells for chronic myelogenous leukemia. Hematol. Oncol. 24(3), 151-158 (2006). (Pubitemid 44483909)
    • (2006) Hematological Oncology , vol.24 , Issue.3 , pp. 151-158
    • Li, X.1    Lu, Y.2    Huang, W.3    Xu, H.4    Chen, X.5    Geng, Q.6    Fan, H.7    Tan, Y.8    Xue, G.9    Jiang, X.10
  • 41
    • 77957751719 scopus 로고    scopus 로고
    • Intranigral transplantation of epigenetically induced BDNF-secreting human mesenchymal stem cells: Implications for cell-based therapies in Parkinson's disease
    • Somoza R, Juri C, Baes M, Wyneken U, Rubio FJ. Intranigral transplantation of epigenetically induced BDNF-secreting human mesenchymal stem cells: implications for cell-based therapies in Parkinson's disease. Biol. Blood Marrow Transplant. 16(11), 1530-1540 (2010).
    • (2010) Biol. Blood Marrow Transplant. , vol.16 , Issue.11 , pp. 1530-1540
    • Somoza, R.1    Juri, C.2    Baes, M.3    Wyneken, U.4    Rubio, F.J.5
  • 42
    • 77956393300 scopus 로고    scopus 로고
    • The neuroprotective effect of erythropoietintransduced human mesenchymal stromal cells in an animal model of ischemic stroke
    • Cho GW, Koh SH, Kim MH et al. The neuroprotective effect of erythropoietintransduced human mesenchymal stromal cells in an animal model of ischemic stroke. Brain Res. 1353, 1-13 (2010).
    • (2010) Brain Res. , vol.1353 , pp. 1-13
    • Cho, G.W.1    Koh, S.H.2    Kim, M.H.3
  • 43
    • 79959895117 scopus 로고    scopus 로고
    • Effects of transplantation with bone marrow-derived mesenchymal stem cells modified by survivin on experimental stroke in rats
    • Liu N, Zhang Y, Fan L et al. Effects of transplantation with bone marrow-derived mesenchymal stem cells modified by survivin on experimental stroke in rats. J. Transl. Med. 9, 105 (2011).
    • (2011) J. Transl. Med. , vol.9 , pp. 105
    • Liu, N.1    Zhang, Y.2    Fan, L.3
  • 44
    • 59749103836 scopus 로고    scopus 로고
    • Therapeutic benefits of angiogenetic gene-modified human mesenchymal stem cells after cerebral ischemia
    • Toyama K, Honmou O, Harada K et al. Therapeutic benefits of angiogenetic gene-modified human mesenchymal stem cells after cerebral ischemia. Exp. Neurol. 216(1), 47-55 (2009).
    • (2009) Exp. Neurol. , vol.216 , Issue.1 , pp. 47-55
    • Toyama, K.1    Honmou, O.2    Harada, K.3
  • 45
    • 79953794756 scopus 로고    scopus 로고
    • VEGF-expressing human umbilical cord mesenchymal stem cells, an improved therapy strategy for Parkinson's disease
    • Xiong N, Zhang Z, Huang J et al. VEGF-expressing human umbilical cord mesenchymal stem cells, an improved therapy strategy for Parkinson's disease. Gene Ther. 18(4), 394-402 (2011).
    • (2011) Gene Ther. , vol.18 , Issue.4 , pp. 394-402
    • Xiong, N.1    Zhang, Z.2    Huang, J.3
  • 46
    • 18144393448 scopus 로고    scopus 로고
    • Therapeutic benefit of TH-engineered mesenchymal stem cells for Parkinson's disease
    • DOI 10.1016/j.brainresprot.2005.03.002, PII S1385299X05000280
    • Lu L, Zhao C, Liu Y et al. Therapeutic benefit of TH-engineered mesenchymal stem cells for Parkinson's disease. Brain Res. Brain Res. Protoc. 15(1), 46-51 (2005). (Pubitemid 40616871)
    • (2005) Brain Research Protocols , vol.15 , Issue.1 , pp. 46-51
    • Lu, L.1    Zhao, C.2    Liu, Y.3    Sun, X.4    Duan, C.5    Ji, M.6    Zhao, H.7    Xu, Q.8    Yang, H.9
  • 47
    • 79956037142 scopus 로고    scopus 로고
    • Encapsulated native and glucagon-like peptide-1 transfected human mesenchymal stem cells in a transgenic mouse model of Alzheimer's disease
    • Klinge PM, Harmening K, Miller MC et al. Encapsulated native and glucagon-like peptide-1 transfected human mesenchymal stem cells in a transgenic mouse model of Alzheimer's disease. Neurosci. Lett. 497(1), 6-10 (2011).
    • (2011) Neurosci. Lett. , vol.497 , Issue.1 , pp. 6-10
    • Klinge, P.M.1    Harmening, K.2    Miller, M.C.3
  • 48
    • 34848880924 scopus 로고    scopus 로고
    • Enhancing effect of IL-1alpha on neurogenesis from adult human mesenchymal stem cells: Implication for inflammatory mediators in regenerative medicine
    • Greco SJ, Rameshwar P. Enhancing effect of IL-1alpha on neurogenesis from adult human mesenchymal stem cells: implication for inflammatory mediators in regenerative medicine. J. Immunol. 179(5), 3342-3350 (2007).
    • (2007) J. Immunol. , vol.179 , Issue.5 , pp. 3342-3350
    • Greco, S.J.1    Rameshwar, P.2
  • 49
    • 79958059544 scopus 로고    scopus 로고
    • Variable behavior and complications of autologous bone marrow mesenchymal stem cells transplanted in experimental autoimmune encephalomyelitis
    • Grigoriadis N, Lourbopoulos A, Lagoudaki R et al. Variable behavior and complications of autologous bone marrow mesenchymal stem cells transplanted in experimental autoimmune encephalomyelitis. Exp. Neurol. 230(1), 78-89 (2011).
    • (2011) Exp. Neurol. , vol.230 , Issue.1 , pp. 78-89
    • Grigoriadis, N.1    Lourbopoulos, A.2    Lagoudaki, R.3
  • 50
    • 79958021185 scopus 로고    scopus 로고
    • The risk of putting something where it does not belong: Mesenchymal stem cells produce masses in the brain
    • Snyder EY. The risk of putting something where it does not belong: mesenchymal stem cells produce masses in the brain. Exp. Neurol. 230(1), 75-77 (2011).
    • (2011) Exp. Neurol. , vol.230 , Issue.1 , pp. 75-77
    • Snyder, E.Y.1
  • 51
    • 79960426672 scopus 로고    scopus 로고
    • Stem cells and growth factor delivery systems for cardiovascular disease
    • Madonna R, De Caterina R. Stem cells and growth factor delivery systems for cardiovascular disease. J. Biotechnol. 154(4), 291-297 (2011).
    • (2011) J. Biotechnol. , vol.154 , Issue.4 , pp. 291-297
    • Madonna, R.1    De Caterina, R.2
  • 52
    • 69849084725 scopus 로고    scopus 로고
    • Mesenchymal stem cells over-expressing SDF-1 promote angiogenesis and improve heart function in experimental myocardial infarction in rats
    • Tang J, Wang J, Yang J et al. Mesenchymal stem cells over-expressing SDF-1 promote angiogenesis and improve heart function in experimental myocardial infarction in rats. Eur. J. Cardiothorac. Surg. 36(4), 644-650 (2009).
    • (2009) Eur. J. Cardiothorac. Surg. , vol.36 , Issue.4 , pp. 644-650
    • Tang, J.1    Wang, J.2    Yang, J.3
  • 53
    • 58149345104 scopus 로고    scopus 로고
    • IGF-1-overexpressing mesenchymal stem cells accelerate bone marrow stem cell mobilization via paracrine activation of SDF-1alpha/CXCR4 signaling to promote myocardial repair
    • Haider H, Jiang S, Idris NM, Ashraf M. IGF-1-overexpressing mesenchymal stem cells accelerate bone marrow stem cell mobilization via paracrine activation of SDF-1alpha/CXCR4 signaling to promote myocardial repair. Circ. Res. 103(11), 1300-1308 (2008).
    • (2008) Circ. Res. , vol.103 , Issue.11 , pp. 1300-1308
    • Haider, H.1    Jiang, S.2    Idris, N.M.3    Ashraf, M.4
  • 54
    • 77953812469 scopus 로고    scopus 로고
    • Genetic modification of mesenchymal stem cells overexpressing CCR1 increases cell viability, migration, engraftment, and capillary density in the injured myocardium
    • Study demonstrates how gene therapy can be utilized to promote the regenerative capabilities of transplanted MSCs
    • Huang J, Zhang Z, Guo J et al. Genetic modification of mesenchymal stem cells overexpressing CCR1 increases cell viability, migration, engraftment, and capillary density in the injured myocardium. Circ. Res. 106(11), 1753-1762 (2010). Study demonstrates how gene therapy can be utilized to promote the regenerative capabilities of transplanted MSCs.
    • (2010) Circ. Res. , vol.106 , Issue.11 , pp. 1753-1762
    • Huang, J.1    Zhang, Z.2    Guo, J.3
  • 55
    • 10744233934 scopus 로고    scopus 로고
    • Treatment of myocardial ischemia with bone marrowderived mesenchymal stem cells overexpressing hepatocyte growth factor
    • Duan HF, Wu CT, Wu DL et al. Treatment of myocardial ischemia with bone marrowderived mesenchymal stem cells overexpressing hepatocyte growth factor. Mol. Ther. 8(3), 467-474 (2003).
    • (2003) Mol. Ther. , vol.8 , Issue.3 , pp. 467-474
    • Duan, H.F.1    Wu, C.T.2    Wu, D.L.3
  • 58
    • 79959526392 scopus 로고    scopus 로고
    • Ex vivo generation of a highly potent population of circulating angiogenic cells using a collagen matrix
    • Kuraitis D, Hou C, Zhang Y et al. Ex vivo generation of a highly potent population of circulating angiogenic cells using a collagen matrix. J. Mol. Cell. Cardiol. 51(2), 187-197 (2011).
    • (2011) J. Mol. Cell. Cardiol. , vol.51 , Issue.2 , pp. 187-197
    • Kuraitis, D.1    Hou, C.2    Zhang, Y.3
  • 59
    • 79956371111 scopus 로고    scopus 로고
    • Composite scaffold provides a cell delivery platform for cardiovascular repair
    • Godier-Furnemont AF, Martens TP, Koeckert MS et al. Composite scaffold provides a cell delivery platform for cardiovascular repair. Proc. Natl Acad. Sci. USA 108(19), 7974-7979 (2011).
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , Issue.19 , pp. 7974-7979
    • Godier-Furnemont, A.F.1    Martens, T.P.2    Koeckert, M.S.3
  • 60
    • 80053908371 scopus 로고    scopus 로고
    • A collagen peptide-based physical hydrogel for cell encapsulation
    • Perez CM, Panitch A, Chmielewski J. A collagen peptide-based physical hydrogel for cell encapsulation. Macromol. Biosci. 11(10), 1426-1431 (2011).
    • (2011) Macromol. Biosci. , vol.11 , Issue.10 , pp. 1426-1431
    • Perez, C.M.1    Panitch, A.2    Chmielewski, J.3
  • 61
    • 80051550620 scopus 로고    scopus 로고
    • The fast release of stem cells from alginate-fibrin microbeads in injectable scaffolds for bone tissue engineering
    • Zhou H, Xu HH. The fast release of stem cells from alginate-fibrin microbeads in injectable scaffolds for bone tissue engineering. Biomaterials 32(30), 7503-7513 (2011).
    • (2011) Biomaterials , vol.32 , Issue.30 , pp. 7503-7513
    • Zhou, H.1    Xu, H.H.2
  • 62
    • 80052833354 scopus 로고    scopus 로고
    • Mesenchymal stem cells stably transduced with a dominant-negative inhibitor of CCL2 greatly attenuate bleomycin-induced lung damage
    • Saito S, Nakayama T, Hashimoto N et al. Mesenchymal stem cells stably transduced with a dominant-negative inhibitor of CCL2 greatly attenuate bleomycin-induced lung damage. Am. J. Pathol. 179(3), 1088-1094 (2011).
    • (2011) Am. J. Pathol. , vol.179 , Issue.3 , pp. 1088-1094
    • Saito, S.1    Nakayama, T.2    Hashimoto, N.3
  • 63
    • 33747186449 scopus 로고    scopus 로고
    • Implantation of mesenchymal stem cells overexpressing endothelial nitric oxide synthase improves right ventricular impairments caused by pulmonary hypertension
    • DOI 10.1161/CIRCULATIONAHA.105.001487, PII 0000301720060704100030
    • Kanki-Horimoto S, Horimoto H, Mieno S et al. Implantation of mesenchymal stem cells overexpressing endothelial nitric oxide synthase improves right ventricular impairments caused by pulmonary hypertension. Circulation 114(Suppl. 1), I181-I185 (2006). (Pubitemid 44297148)
    • (2006) Circulation , vol.114 , Issue.SUPPL. 1
    • Kanki-Horimoto, S.1    Horimoto, H.2    Mieno, S.3    Kishida, K.4    Watanabe, F.5    Furuya, E.6    Katsumata, T.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.