The developability of heteroaromatic and heteroaliphatic rings - Do some have a better pedigree as potential drug molecules than others?

MedChemComm

Volumn 3, Issue 9, 2012, Pages 1062-1069

  Ritchie, Timothy J ^a   MacDonald, Simon J F ^b   Peace, Simon ^b   Pickett, Stephen D ^b   Luscombe, Christopher N ^b  

^a TJR Chem   (Italy)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,3 TRIAZOLE DERIVATIVE; 1,2,4 OXADIAZOLE DERIVATIVE; 1,2,4 TRIAZOLE DERIVATIVE; 1,3 THIAZOLIDINE DERIVATIVE; 1,3,4 OXADIAZOLE DERIVATIVE; ALIPHATIC COMPOUND; AROMATIC COMPOUND; CYTOCHROME P450; FURAN DERIVATIVE; IMIDAZOLE DERIVATIVE; IMIDAZOLINE DERIVATIVE; ISOXAZOLE DERIVATIVE; MORPHOLINE DERIVATIVE; OXAZOLE DERIVATIVE; PIPERIDINE DERIVATIVE; PIPERIZINE DERIVATIVE; PYRAZINE DERIVATIVE; PYRAZOLE DERIVATIVE; PYRIDAZINE DERIVATIVE; PYRIDINE DERIVATIVE; PYRIMIDINE DERIVATIVE; PYRROLE DERIVATIVE; PYRROLIDINE DERIVATIVE; SERUM ALBUMIN; TETRAHYDROFURAN DERIVATIVE; TETRAZOLE DERIVATIVE; THIAZOLE DERIVATIVE; THIOPHENE DERIVATIVE; TRIAZINE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; DRUG SOLUBILITY; DRUG STRUCTURE; ENZYME INHIBITION; PRIORITY JOURNAL; PROTEIN BINDING;

EID: 84865491027     PISSN: 20402503     EISSN: 20402511     Source Type: Journal    
DOI: 10.1039/c2md20111a     Document Type: Article

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