-
1
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch TJ, Bell DW, Sordella R et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004; 350(21): 2129-2139.
-
(2004)
N Engl J Med
, vol.350
, Issue.21
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
-
2
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Paez JG, Jänne PA, Lee JC et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004; 304(5676): 1497-1500.
-
(2004)
Science
, vol.304
, Issue.5676
, pp. 1497-1500
-
-
Paez, J.G.1
Jänne, P.A.2
Lee, J.C.3
-
3
-
-
84887212361
-
Alterations in genes of the EGFR signaling pathway and their relationship to EGFR tyrosine kinase inhibitor sensitivity in lung cancer cell lines
-
Gandhi J, Zhang J, Xie Y et al. Alterations in genes of the EGFR signaling pathway and their relationship to EGFR tyrosine kinase inhibitor sensitivity in lung cancer cell lines. PLoS One 2009; 4(2): e4576.
-
(2009)
PLoS One
, vol.4
, Issue.2
-
-
Gandhi, J.1
Zhang, J.2
Xie, Y.3
-
4
-
-
77955690878
-
Vliv mutací genů EGFR a KRAS na prognózu přežití u pacientů s nemalobuněč ným karcinomem plic, léčených inhibitory tyrosin-kináz (srovnání výsledků léčby gefitinibem a erlotinibem)
-
Minárik M, Benešová L, Belšá nová B et al. Vliv mutací genů EGFR a KRAS na prognózu přežití u pacientů s nemalobuněčným karcinomem plic, léčený ch inhibitory tyrosin-kináz (srovnání výsledků léčby gefitinibem a erlotinibem). Stud Pneumol Phtiseol 2009; 69(3): 96-104.
-
(2009)
Stud Pneumol Phtiseol
, vol.69
, Issue.3
, pp. 96-104
-
-
Minárik, M.1
Benešová, L.2
Belšá nová, B.3
-
5
-
-
24944497744
-
Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib
-
Eberhard DA, Johnson BE, Amler LC et al. Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib. J Clin Oncol 2005; 23(25): 5900-5909.
-
(2005)
J Clin Oncol
, vol.23
, Issue.25
, pp. 5900-5909
-
-
Eberhard, D.A.1
Johnson, B.E.2
Amler, L.C.3
-
6
-
-
78751535304
-
Prognostic and predictive implications of EGFR mutations, EGFR copy number and KRAS mutations in advanced stage lung adenocarcinoma
-
Bonanno L, Schiavon M, Nardo G et al. Prognostic and predictive implications of EGFR mutations, EGFR copy number and KRAS mutations in advanced stage lung adenocarcinoma. Anticancer Res 2010; 30(12): 5121-5128.
-
(2010)
Anticancer Res
, vol.30
, Issue.12
, pp. 5121-5128
-
-
Bonanno, L.1
Schiavon, M.2
Nardo, G.3
-
7
-
-
77955093445
-
Prognostic implications of epidermal growth factor receptor and KRAS gene mutations and epidermal growth factor receptor gene copy numbers in patients with surgically resectable non-small cell lung cancer in Taiwan
-
Liu HP, Isaac Wu HD, Chang JW et al. Prognostic implications of epidermal growth factor receptor and KRAS gene mutations and epidermal growth factor receptor gene copy numbers in patients with surgically resectable non-small cell lung cancer in Taiwan. J Thorac Oncol 2010; 5(8): 1175-1184.
-
(2010)
J Thorac Oncol
, vol.5
, Issue.8
, pp. 1175-1184
-
-
Liu, H.P.1
Isaac Wu, H.D.2
Chang, J.W.3
-
8
-
-
52049090365
-
Role of KRAS and EGFR as biomarkers of response to erlotinib in National Cancer Institute of Canada Clinical Trials Group Study BR.21
-
Zhu CQ, da Cunha Santos G, Ding K et al. Role of KRAS and EGFR as biomarkers of response to erlotinib in National Cancer Institute of Canada Clinical Trials Group Study BR.21. J Clin Oncol 2008; 26(26): 4268-4275.
-
(2008)
J Clin Oncol
, vol.26
, Issue.26
, pp. 4268-4275
-
-
Zhu, C.Q.1
Da Cunha Santos, G.2
Ding, K.3
-
9
-
-
33750962024
-
Molecular predictors of outcome with gefitinib in a phase III placebo-controlled study in advanced non-small-cell lung cancer
-
Hirsch FR, Varella-Garcia M, Bunn PA Jr et al. Molecular predictors of outcome with gefitinib in a phase III placebo-controlled study in advanced non-small-cell lung cancer. J Clin Oncol 2006; 24(31): 5034-5042.
-
(2006)
J Clin Oncol
, vol.24
, Issue.31
, pp. 5034-5042
-
-
Hirsch, F.R.1
Varella-Garcia, M.2
Bunn Jr., P.A.3
-
10
-
-
77649222572
-
Molecular predictors of outcome with gefitinib and docetaxel in previously treated non-small-cell lung cancer: Data from the randomized phase III INTEREST trial
-
Douillard JY, Shepherd FA, Hirsh V et al. Molecular predictors of outcome with gefitinib and docetaxel in previously treated non-small-cell lung cancer: data from the randomized phase III INTEREST trial. J Clin Oncol 2010; 28(5): 744-752.
-
(2010)
J Clin Oncol
, vol.28
, Issue.5
, pp. 744-752
-
-
Douillard, J.Y.1
Shepherd, F.A.2
Hirsh, V.3
-
11
-
-
77953541527
-
Erlotinib as maintenance treatment in advanced non-small-cell lung cancer. A multicentre, randomised, placebo-controlled phase3study
-
Cappuzzo F, Ciuleanu T, Stelmakh L et al. Erlotinib as maintenance treatment in advanced non-small-cell lung cancer. a multicentre, randomised, placebo-controlled phase3study Lancet Oncol 2010; 11(6): 521-529.
-
(2010)
Lancet Oncol
, vol.11
, Issue.6
, pp. 521-529
-
-
Cappuzzo, F.1
Ciuleanu, T.2
Stelmakh, L.3
-
12
-
-
70349476965
-
Biomarker analyses from the phase III placebo-controlled SATURN study of maintenance erlotinib following first-line chemotherapy for advanced NSCLC
-
Abstract 8020
-
Brugger W, Triller N, Blasinska-Morawiec M et al. Biomarker analyses from the phase III placebo-controlled SATURN study of maintenance erlotinib following first-line chemotherapy for advanced NSCLC. J Clin Oncol 2009; 27 (Suppl): 15. Abstract 8020.
-
(2009)
J Clin Oncol
, vol.27
, Issue.SUPPL.
, pp. 15
-
-
Brugger, W.1
Triller, N.2
Blasinska-Morawiec, M.3
-
13
-
-
69249173084
-
Dominance of EGFR and insignificant KRAS mutations in prediction of tyrosine-kinase therapy for NSCLC patients stratified by tumor subtype and smoking status
-
Pesek M, Benesova L, Belsanova B et al. Dominance of EGFR and insignificant KRAS mutations in prediction of tyrosine-kinase therapy for NSCLC patients stratified by tumor subtype and smoking status. Anticancer Res 2009; 29(7): 2767-2773.
-
(2009)
Anticancer Res
, vol.29
, Issue.7
, pp. 2767-2773
-
-
Pesek, M.1
Benesova, L.2
Belsanova, B.3
-
14
-
-
68949201629
-
Activating and resistance mutations of EGFR in non-small-cell lung cancer. Role in clinical response to EGFR tyrosine kinase inhibitors
-
Gazdar AF. Activating and resistance mutations of EGFR in non-small-cell lung cancer. role in clinical response to EGFR tyrosine kinase inhibitors. Oncogene 2009; 28 (Suppl 1): S24-S31.
-
(2009)
Oncogene
, vol.28
, Issue.SUPPL. 1
-
-
Gazdar, A.F.1
-
15
-
-
79958020132
-
EGFR-mutated lung cancer: A paradigm of molecular oncology
-
Zhang Z, Stiegler AL, Boggon TJ et al. EGFR-mutated lung cancer: a paradigm of molecular oncology. Oncotarget 2010; 1(7): 497-514.
-
(2010)
Oncotarget
, vol.1
, Issue.7
, pp. 497-514
-
-
Zhang, Z.1
Stiegler, A.L.2
Boggon, T.J.3
-
16
-
-
33947498978
-
Molecular predictors of response to epidermal growth factor receptor antagonists in non-small-cell lung cancer
-
Sequist LV, Bell DW, Lynch TJ et al. Molecular predictors of response to epidermal growth factor receptor antagonists in non-small-cell lung cancer. J Clin Oncol 2007; 25(5): 587-595.
-
(2007)
J Clin Oncol
, vol.25
, Issue.5
, pp. 587-595
-
-
Sequist, L.V.1
Bell, D.W.2
Lynch, T.J.3
-
17
-
-
67649414622
-
Individualizing therapy for non-small-cell lung cancer: A paradigm shift from empiric to integrated decision-making
-
Gandara DR, Lara PN Jr, Mack P et al. Individualizing therapy for non-small-cell lung cancer: a paradigm shift from empiric to integrated decision-making. Clin Lung Cancer 2009; 10(3): 148-150.
-
(2009)
Clin Lung Cancer
, vol.10
, Issue.3
, pp. 148-150
-
-
Gandara, D.R.1
Lara Jr., P.N.2
Mack, P.3
-
18
-
-
69349085331
-
Molecular analysis-based treatment strategies for the management of non-small cell lung cancer
-
West H, Lilenbaum R, Harpole D et al. Molecular analysis-based treatment strategies for the management of non-small cell lung cancer. J Thorac Oncol 2009; 4 (9 Suppl 2): S1029-S1039.
-
(2009)
J Thorac Oncol
, vol.4
, Issue.9 SUPPL. 2
-
-
West, H.1
Lilenbaum, R.2
Harpole, D.3
-
19
-
-
57549098807
-
The Catalogue of Somatic Mutations in Cancer (COSMIC)
-
Chapter 10: Unit 10.11
-
Forbes SA, Bhamra G, Bamford S et al. The Catalogue of Somatic Mutations in Cancer (COSMIC). Curr Protoc Hum Genet 2008; Chapter 10: Unit 10.11.
-
(2008)
Curr Protoc Hum Genet
-
-
Forbes, S.A.1
Bhamra, G.2
Bamford, S.3
-
20
-
-
79954741752
-
Efficacy of gefitinib for non-adenocarcinoma non-small-cell lung cancer patients harboring epidermal growth factor receptor mutations: A pooled analysis of published reports
-
Shukuya T, Takahashi T, Kaira R et al. Efficacy of gefitinib for non-adenocarcinoma non-small-cell lung cancer patients harboring epidermal growth factor receptor mutations: a pooled analysis of published reports. Cancer Sci 2011; 102(5): 1032-1037.
-
(2011)
Cancer Sci
, vol.102
, Issue.5
, pp. 1032-1037
-
-
Shukuya, T.1
Takahashi, T.2
Kaira, R.3
-
21
-
-
52049099853
-
PIK3CA mutations and copy number gains in human lung cancers
-
Yamamoto H, Shigematsu H, Nomura M et al. PIK3CA mutations and copy number gains in human lung cancers. Cancer Res 2008; 68(17): 6913-6921.
-
(2008)
Cancer Res
, vol.68
, Issue.17
, pp. 6913-6921
-
-
Yamamoto, H.1
Shigematsu, H.2
Nomura, M.3
-
22
-
-
77955277111
-
Effects of KRAS, BRAF, NRAS and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: A retrospective consortium analysis
-
De Roock W, Claes B, Bernasconi D et al. Effects of KRAS, BRAF, NRAS and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis. Lancet Oncol 2010; 11(8): 753-762.
-
(2010)
Lancet Oncol
, vol.11
, Issue.8
, pp. 753-762
-
-
De Roock, W.1
Claes, B.2
Bernasconi, D.3
-
23
-
-
33751084640
-
PIK3CA mutation status in Japanese lung cancer patients
-
Kawano O, Sasaki H, Endo K et al. PIK3CA mutation status in Japanese lung cancer patients. Lung Cancer 2006; 54(2): 209-215.
-
(2006)
Lung Cancer
, vol.54
, Issue.2
, pp. 209-215
-
-
Kawano, O.1
Sasaki, H.2
Endo, K.3
-
24
-
-
78149470440
-
Somatic mutations in epidermal growth factor receptor signaling pathway genes in non-small cell lung cancers
-
Lee SY, Kim MJ, Jin G et al. Somatic mutations in epidermal growth factor receptor signaling pathway genes in non-small cell lung cancers. J Thorac Oncol 2010; 5(11): 1734-1740.
-
(2010)
J Thorac Oncol
, vol.5
, Issue.11
, pp. 1734-1740
-
-
Lee, S.Y.1
Kim, M.J.2
Jin, G.3
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