Bioreactors in regenerative medicine - From a technical device to a reconstructive alternative?;Bioreaktoren in der Regenerativen Medizin - Vom technischen Apparat zur rekonstruktiven Alternative?

Handchirurgie Mikrochirurgie Plastische Chirurgie

Volumn 44, Issue 4, 2012, Pages 198-203

  Polykandriotis, E ^a,c   Schmidt, V J ^a   Kneser, U ^a   Jianming, S ^b   Boccaccini, A R ^d   Horch, R E ^a  

^a UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c SANA KLINIKUM OFFENBACH   (Germany)

^d UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

angiogenesis; bioreactors; experimental transplantation; growth factors; negative pressure therapy; tissue engineering

Indexed keywords

ANGIOGENESIS; ANIMAL; ARTICLE; BIOREACTOR; COMPARATIVE STUDY; CULTURE TECHNIQUE; EQUIPMENT DESIGN; HUMAN; INSTRUMENTATION; PHYSIOLOGY; PLASTIC SURGERY; RAT; REGENERATIVE MEDICINE; SCANNING ELECTRON MICROSCOPY; TISSUE ENGINEERING; TRANSLATIONAL RESEARCH; VACUUM ASSISTED CLOSURE; WOUND HEALING;

ANIMALS; BIOREACTORS; CELL CULTURE TECHNIQUES; EQUIPMENT DESIGN; HUMANS; MICROSCOPY, ELECTRON, SCANNING; NEGATIVE-PRESSURE WOUND THERAPY; NEOVASCULARIZATION, PHYSIOLOGIC; RATS; RECONSTRUCTIVE SURGICAL PROCEDURES; REGENERATIVE MEDICINE; TISSUE ENGINEERING; TRANSLATIONAL MEDICAL RESEARCH; WOUND HEALING;

EID: 84865481028     PISSN: 07221819     EISSN: 14393980     Source Type: Journal    
DOI: 10.1055/s-0032-1321838     Document Type: Article

References (36)

1. Carpentier B, Gautier A, Legallais C. Artificial and bioartificial liver devices: present and future. Gut: 2009; 58 1690 1702 58/12/1690 [pii]10.1136/gut.2008.175380 [doi]
2. Horch R E, Kneser U, Polykandriotis E et al. Tissue engineering and regenerative medicine - where do we stand? J Cell Mol Med 16 1157 1165 10.1111/j.1582-4934.2012.01564.x [doi]
3. Cormier J T, zur Nieden N I, Rancourt D E et al. Expansion of undifferentiated murine embry-onic stem cells as aggregates in suspension culture bioreactors. Tissue Eng: 2006; 12 3233 3245 10.1089/ten.2006.12.3233 [doi] (Pubitemid 44846427)
4. Fok E Y, Zandstra P W. Shear-controlled single-step mouse embryonic stem cell expansion and embryoid body-based differentiation. Stem Cells: 2005; 23 1333 1342 2005-0112 [pii] 10.1634/stemcells.2005-0112 [doi] (Pubitemid 41504921)
5. Rath S N, Strobel L A, Arkudas A et al. Osteoinduction and survival of osteoblasts and bone-marrow stromal cells in 3D biphasic calcium phosphate scaffolds under static and dynamic culture conditions. J Cell Mol Med 10.1111/j.1582-4934.2012.01545.x [doi]
6. Bleiziffer O, Hammon M, Naschberger E et al. Endothelial progenitor cells are integrated in newly formed capillaries and alter adjacent fibrovascular tissue after subcutaneous implantation in a fibrin matrix. J Cell Mol Med 15 2452 2461 10.1111/j.1582-4934.2010.01247.x [doi]
7. Sanford G L, Ellerson D, Melhado-Gardner C et al. Three-dimensional growth of endothelial cells in the microgravity-based rotating wall vessel bioreactor. In Vitro Cell Dev Biol Anim: 2002; 38 493 504, 10.1290/1071- 2690(2002)038<0493:TGOECI>2.0.CO;2 [doi] (Pubitemid 36514560)
8. Unsworth B R, Lelkes P I. Growing tissues in microgravity. Nat Med: 1998; 4 901 907 (Pubitemid 28364028)
9. Boos A M, Loew J S, Deschler G et al. Directly auto-transplanted mesenchymal stem cells induce bone formation in a ceramic bone substitute in an ectopic sheep model. J Cell Mol Med 15 1364 1378 JCMM1131 [pii] 10.1111/j.1582-4934.2010.01131.x [doi]
10. Hildebrand D K, Wu Z J, Mayer J E Jr et al. Design and hydrodynamic evaluation of a novel pulsatile bioreactor for biologically active heart valves. Ann Biomed Eng: 2004; 32 1039 1049
11. Hoenig E, Winkler T, Mielke G et al. High amplitude direct compressive strain enhances mechanical properties of scaffold-free tissue-engineered cartilage. Tissue Eng Part A 17 1401 1411 10.1089/ten.TEA.2010.0395 [doi]
12. Drolz A, Saxa R, Scherzer T et al. Extracorporeal artificial liver support in hypoxic liver injury. Liver Int; 31 03 19 23 10.1111/j.1478-3231. 2011.02583.x [doi]
13. Leffler M, Derrick K L, McNulty A et al. Changes of anabolic processes at the cellular and molecular level in chronic wounds under topical negative pressure can be revealed by transcriptome analysis. J Cell Mol Med 15 1564 1571 JCMM1147 [pii] 10.1111/j.1582-4934.2010.01147.x [doi]
14. Leffler M, Derrick K L, McNulty A et al. Changes of anabolic processes at the cellular and molecular level in chronic wounds under topical negative pressure can be revealed by transcriptome analysis. J Cell Mol Med: 2011; 15 1564 1571 10.1111/j.1582-4934.2010.01147.x
15. Kopp J, Kneser U, Bach A D et al. Buried chip skin grafting in neuropathic diabetic foot ulcers following vacuum-assisted wound bed preparation: enhancing a classic surgical tool with no-vel technologies. The international journal of lower extremity wounds: 2004; 3 168 171, 10.1177/1534734604268092
16. Moiemen N S, Yarrow J, Kamel D et al. Topical negative pressure therapy: does it accelerate neovascularisation within the dermal regeneration template, Integra? A prospective histological in vivo study. Burns 36 764 768, S0305-4179(10)00107-5 [pii] 101016/j.burns.2010.04.011 [doi]
17. Lantis Ii J C. Update 2012: Regenerative Medicine in Wounds: Current Use of Growth Factors, Cell Therapy, and Negative Pressure Wound Therapy for Chronic Wounds. Surg Technol Int; XXI 43 49 sti21/43 [pii]
18. Scimeca C L, Bharara M, Fisher T K et al. Novel use of insulin in continuous-instillation negative pressure wound therapy as "wound chemotherapyo" J Diabetes Sci Technol 4 820 824
19. Kneser U, Kaufmann P M, Fiegel H C et al. Long-term differentiated function of heterotopically transplanted hepatocytes on three-dimensional polymer matrices. J Biomed Mater Res: 1999; 47 494 503 10.1002/(SICI)1097- 4636(19991215)47:4<494::AID-JBM5>3.0.CO;2-L [pii] (Pubitemid 29468553)
20. Warnke P H, Springer I N, Wiltfang J et al. Growth and transplantation of a custom vascularised bone graft in a man. Lancet: 2004; 364 766 770 10.1016/S0140-6736(04)16935-3 (Pubitemid 39165095)
21. Boos A M, Loew J S, Deschler G et al. Directly auto-transplanted mesenchymal stem cells induce bone formation in a ceramic bone substitute in an ectopic sheep model. J Cell Mol Med: 2011; 15 1364 1378 10.1111/j.1582-4934. 2010.01131.x
22. Bleiziffer O, Hammon M, Naschberger E et al. Endothelial progenitor cells are integrated in newly formed capillaries and alter adjacent fibrovascular tissue after subcutaneous implantation in a fibrin matrix. J Cell Mol Med: 2011; 15 2452 2461 10.1111/j.1582-4934.2010.01247.x
23. Polykandriotis E, Drakotos D, Arkudas A et al. Factors influencing successful outcome in the arteriovenous loop model: a retrospective study of 612 loop operations. J Reconstr Microsurg: 2011; 27 11 18 10.1055/s-0030-1267385
24. Polykandriotis E, Tjiawi J, Euler S et al. The venous graft as an effector of early angiogenesis in a fibrin matrix. Microvasc Res: 2008; 75 25 33 10.1016/j.mvr.2007.04.003 (Pubitemid 350266730)
25. Lansley S M, Searles R G, Hoi A et al. Mesothelial cell differentiation into osteoblast- and adipocyte-like cells. J Cell Mol Med: 2011; 15 2095 2105 10.1111/j.1582-4934.2010.01212.x
26. Boos A M, Arkudas A, Kneser U et al. Bone tissue engineering for bone defect therapy. Handchir Mikrochir Plast Chir: 2010; 42 360 368 10.1055/s-0030-1261964
27. Horch R E. Tissue engineering in plastic and reconstructive surgery. Handchir Mikrochir Plast Chir: 2010; 42 327 328 10.1055/s-0030-1268460
28. Klumpp D, Horch R E, Kneser U et al. Engineering skeletal muscle tissue - new perspectives in vitro and in vivo. J Cell Mol Med: 2010; 14 2622 2329 10.1111/j.1582-4934.2010.01183.x
29. Polykandriotis E, Arkudas A, Euler S et al. Prevascularisation strategies in tissue engineering. Handchir Mikrochir Plast Chir: 2006; 38 217 223 10.1055/s-2006-924419 (Pubitemid 44433762)
30. Beier J P, Hess A, Loew J et al. De novo generation of an axially vascularized processed bovine cancellous-bone substitute in the sheep arteriovenous-loop model. Eur Surg Res: 2011; 46 148 155, 10.1159/000324408
31. Fang J S, Angelov S N, Simon A M et al. Cx37 deletion enhances vascular growth and facilitates ischemic limb recovery. Am J Physiol Heart Circ Physiol: 2011; 301 H1872 H1881 ajpheart.00683.2011 [pii] 10.1152/ajpheart.00683.2011
32. Buschmann I, Pries A, Styp-Rekowska B et al. Pulsatile shear and Gja5 modulate arterial identity and remodeling events during flow-driven arteriogenesis. Development: 2010; 137 2187 2196, 137/13/2187 [pii] 10.1242/dev.045351
33. Schmidt V J, Wolfle S E, Boettcher M et al. Gap junctions synchronize vascular tone within the microcirculation. Pharmacol Rep: 2008; 60 68 74 (Pubitemid 351586544)
34. Polykandriotis E, Popescu L M, Horch R E. Regenerative medicine: then and now - an update of recent history into future possibilities. J Cell Mol Med 2010; 14: 2350-2358 10.1111/j.1582-4934.2010.01169.x
35. Dragu A, Schnurer S, Surmann-Schmitt C et al. Gene expression analysis of ischaemia and reperfusion in human microsurgical free muscle tissue transfer. J Cell Mol Med 15 983 993 JCMM1061 [pii] 10.1111/j.1582-4934.2010.01061.x [doi]
36. Thomson H. Bioprocessing of embryonic stem cells for drug discovery. Trends Biotechnol: 2007; 25 224 230 S0167-7799(07)00074-1 [pii] 10.1016/j.tibtech.2007.03.003 (Pubitemid 46591928)