Estimating the whole bone-marrow asset in humans by a computational approach to integrated PET/CT imaging

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 39, Issue 8, 2012, Pages 1326-1338

  Sambuceti, Gianmario ^a,b,c   Brignone, Massimo ^a,d   Marini, Cecilia ^b   Massollo, Michela ^a   Fiz, Francesco ^a,c   Morbelli, Silvia ^a   Buschiazzo, Ambra ^a   Campi, Cristina ^e   Piva, Roberta ^a   Massone, Anna Maria ^g   Piana, Michele ^d,g   Frassoni, Francesco ^f  

^a UNIVERSITY OF GENOA   (Italy)

^b CNR   (Italy)

^c Advanced Biotechnology Center   (Italy)

^d UNIVERSITY OF GENOA   (Italy)

^e UNIVERSITY OF HELSINKI   (Finland)

^f G GASLINI INSTITUTE   (Italy)

^g CNR SPIN   (Italy)

Author keywords

Bone marrow imaging; Image processing; PET CT

Indexed keywords

FLUORODEOXYGLUCOSE F 18;

ADULT; ARTICLE; B LYMPHOCYTE; BODY WEIGHT; BONE MARROW; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CONTROLLED STUDY; FEMALE; GLUCOSE TRANSPORT; HUMAN; IMAGE ANALYSIS; INTRAOSSEOUS VOLUME; MAJOR CLINICAL STUDY; MALE; MATHEMATICAL ANALYSIS; METABOLIC RATE; SEX DIFFERENCE; SKELETON; VOLUMETRY; VOXEL BASED MORPHOMETRY; WHOLE BODY PET;

AGE FACTORS; ALGORITHMS; BONE AND BONES; BONE MARROW; DATABASES, FACTUAL; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MALE; MIDDLE AGED; POSITRON-EMISSION TOMOGRAPHY AND COMPUTED TOMOGRAPHY; REPRODUCIBILITY OF RESULTS;

EID: 84865474262     PISSN: 16197070     EISSN: 16197089     Source Type: Journal    
DOI: 10.1007/s00259-012-2141-9     Document Type: Article

References (44)

1. Knowles S, Hoffbrand AV. Bone-marrow aspiration and trephine biopsy (1). Br Med J. 1980;281:204-5.
2. Agool A, Glaudemans AW, Boersma HH, Dierckx RA, Vellenga E, Slart RH. Radionuclide imaging of bone marrow disorders. Eur J Nucl Med Mol Imaging. 2011;38:166-78.
3. Desai AG, Thakur ML. Radiopharmaceuticals for spleen and bone marrow studies. Semin Nucl Med. 1985;15:229-38.
4. Datz FL, Taylor Jr A. The clinical use of radionuclide bone marrow imaging. Semin Nucl Med. 1985;15:239-59.
5. Wahren B, Gahrton G, Hammarstrom S. Nonspecific crossreacting antigen in normal and leukemic myeloid cells and serum of leukemic patients. Cancer Res. 1980;40:2039-44. (Pubitemid 10116134)
6. Mitchell DG, Burk DL, Vinitski S, Rifkin MD. The biophysical basis of tissue contrast in extracranial MR imaging. AJR Am J Roentgenol. 1987;149:831-7. (Pubitemid 17155330)
7. Duda SH, Laniado M, Schick F, Strayle M, Claussen CD. Normal bone marrow in the sacrum of young adults: differences between the sexes seen on chemical-shift MR imaging. Am J Roentgenol. 1995;164:935-40.
8. Kugel H, Jung C, Schulte O, Heindel W. Age-and sex-specific differences in the 1H-spectrum of vertebral bone marrow. J Magn Reson Imaging. 2001;13:263-8. (Pubitemid 32066664)
9. Basu S, Houseni M, Bural G, Chamroonat W, Udupa J, Mishra S, et al. Magnetic resonance imaging based bone marrow segmentation for quantitative calculation of pure red marrow metabolism using 2-deoxy-2-[F-18]fluoro-D- glucose-positron emission tomography: a novel application with significant implications for combined structure-function approach. Mol Imaging Biol. 2007;9:361-5.
10. Blebea JS, Houseni M, Torigian DA, Fan C, Mavi A, Zhuge Y, et al. Structural and functional imaging of normal bone marrow and evaluation ofits age-related changes. Semin Nucl Med. 2007;37:185-94. (Pubitemid 46517466)
11. Fan C, Hernandez-Pampaloni M, Houseni M, Chamroonrat W, Basu S, Kumar R, et al. Age-related changes in the metabolic activity and distribution of the red marrow as demonstrated by 2-deoxy-2-[F-18]fluoro-D-glucose-positron emission tomography. Mol Imaging Biol. 2007;9:300-7. (Pubitemid 47304780)
12. Shreeve WW. Use ofisotopes in the diagnosis of hematopoietic disorders. Exp Hematol. 2007;35:173-9. (Pubitemid 46427996)
13. Kumar R, Alavi A. Fluorodeoxyglucose-PET in the management of breast cancer. Radiol Clin North Am. 2004;42:1113-22. (Pubitemid 39361463)
14. Jhanwar YS, Straus DJ. The role of PET in lymphoma. J Nucl Med. 2006;47:1326-34. (Pubitemid 47544887)
15. Robinson JD, Lupkiewicz SM, Palenik L, Lopez LM, Ariet M. Determination ofideal body weight for drug dosage calculations. Am J Hosp Pharm. 1983;40:1016-9. (Pubitemid 13095552)
16. Chan TF, Vese LA. Active contour without edges. IEEE Trans Image Process. 2001;10:266-77.
17. Abramowitz M, Stegun IA. Handbook of mathematical functions. National Bureau of Standards. Applied Mathematics Series. Washington DC: Tenth Printing; 1972. p. 1020.
18. Dirac P. Principles of quantum mechanics. 4th ed. Oxford: Clarendon Press; 1958.
19. Courant R, Hilbert R. Method of mathematical physics, vol. I. New York: Interscience; 1953.
20. Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet. 1986;1:307-10. (Pubitemid 16134762)
21. Choplin RH, Farber JM, Buckwalter KA, Swan S. Threedimensional volume rendering of the tendons of the ankle and foot. Semin Musculoskelet Radiol. 2004;8:175-83. (Pubitemid 38702986)
22. Mechanik N. Untersuchungen ueber das Gewicht des knochenmark des Menschen. Z Gesamte Anat. 1926;79:58-99.
23. ICRP. Report of the task group on reference man. ICRP publication 23. Oxford: Pergamon Press; 1975.
24. Valentin J. Basic anatomical and physiological data for use in radiological protection: reference values. A report of age-and gender-related differences in the anatomical and physiological characteristics of reference individuals. ICRP Publication 89. Ann ICRP. 2002;32:5-265.
25. Bonner H. The blood and lymphoid organs. In: Rubin E, Farber JL, editors. Pathology. Philadelphia: Lippincott; 1988. p. 1014
26. Atkinson HR. Bone marrow distribution as a factor in estimating radiation to the blood-forming organs: a survey of present knowledge. J Coll Radiol Aust. 1962;6:149-54.
27. WoodardHQ, Holodny E.A summary of the data ofMechanik on the distribution of human bone marrow. Phys Med Biol. 1960;5:57-9.
28. Ellis RE. The distribution of active bone marrow in the adult. Phys Med Biol. 1961;5:255-8.
29. Cristy M. Active bone marrow distribution as a function of age in humans. Phys Med Biol. 1981;26:389-400. (Pubitemid 11096423)
30. Custer RP, Ahlfeldt FE. Studies on the structure and function of bone marrow. II. Variations in cellularity in various bones with advancing years of life and their relative response to stimuli. J Lab Clin Med. 1932;17:960-2.
31. Tavassoli M. Bone marrow: The seedbed of blood. In: Wintrobe MM, editor. Blood, pure and eloquent sh.5. New York: Mc.Graw-Hill Book Company; 1980.
32. Yankelevitz DF, Henschke CI, Davis SD. Percutaneous CT biopsy of chest lesions: an in vitro analysis of the effect of partial volume averaging on needle positioning. AJR Am J Roentgenol. 1993;161:273-8. (Pubitemid 23224785)
33. Aston JA, Cunningham VJ, Asselin MC, Hammers A, Evans AC, Gunn RN. Positron emission tomography partial volume correction: estimation and algorithms. J Cereb Blood Flow Metab. 2002;22:1019-34. (Pubitemid 34831609)
34. Schadendorf D, Dorn-Beineke A, Borelli S, Riethmuller G, Pantel K. Limitations of the immunocytochemical detection ofisolated tumor cells in frozen samples of bone marrow obtained from melanoma patients. Exp Dermatol. 2003;12:165-71. (Pubitemid 36934702)
35. Elder DE. Thin melanoma. Arch Pathol Lab Med. 2011;135:342-6.
36. Denninghoff VC, Falco J, Kahn AG, Trouchot V, Curutchet HP, Elsner B. Sentinel node in melanoma patients: triple negativity with routine techniques and PCR as positive prognostic factor for survival. Mod Pathol. 2008;21:438-44. (Pubitemid 351441032)
37. Thie JA. Clarification of a fractional uptake concept. J Nucl Med. 1995;36:711-2.
38. Thie JA. Understanding the standardized uptake value. Its methods and implications for usage. J Nucl Med. 2004;45:1431-4. (Pubitemid 47618494)
39. Chin BB, Green ED, Turkington TG, Hawk TC, Coleman RE. Increasing uptake time in FDG-PET: standardized uptake values in normal tissues at 1 versus 3 h. Mol Imaging Biol. 2009;11:118-22.
40. Czernin J, Satyamurthy N, Schiepers C. Molecular mechanisms of bone 18F-NaF deposition. J Nucl Med. 2010;51:1826-9.
41. Agool A, Schot BW, Jager PL, Vellenga E. 18F-FLT PET in hematologic disorders: a novel technique to analyze the bone marrow compartment. J Nucl Med. 2006;47:1592-8. (Pubitemid 47545023)
42. Balch CM, Gershenwald JE, Soong SJ, Thompson JF, Atkins MB, Byrd DR, et al. Final version of 2009 AJCC melanoma staging and classification. J Clin Oncol. 2009;27:6199-206.
43. Emery JL, Follett CF. Regression of bone marrow haemopoiesis from the terminal digits in the foetus and infant. Br J Haematol. 1964;10:485-9.
44. Vogler JB, Murphy WA. Bone marrow imaging. Radiology. 1988;168:679-93.