Polyneuropathy while on duodenal levodopa infusion in Parkinson's disease patients: We must be alert

Journal of Neurology

Volumn 259, Issue 8, 2012, Pages 1668-1672

  Santos García, Diego ^a   De La Fuente Fernández, Raúl ^a   Valldeoriola, Francesc ^b   Palasí, Antonio ^b   Carrillo, Fátima ^c   Grande, Mónica ^a   Mir, Pablo ^c,d   De Fabregues, Oriol ^b   Casanova, Jordi ^b  

^a Universidad de La Coruña   (Spain)

^b UNIVERSITY OF BARCELONA   (Spain)

^c Instituto de Biomedicina de Sevilla   (Spain)

^d CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED SOBRE ENFERMEDADES NEURODEGENERATIVAS CIBERNED   (Spain)

Author keywords

Cobalamin; Duodenal levodopa infusion; Guillain Barr syndrome; Homocysteine; Polyneuropathy

Indexed keywords

CYANOCOBALAMIN; FOLIC ACID; HOMOCYSTEINE; LEVODOPA;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTINUOUS INFUSION; CYANOCOBALAMIN DEFICIENCY; DRUG ABSORPTION; DRUG DOSE REDUCTION; DRUG METABOLISM; FEMALE; FOLIC ACID BLOOD LEVEL; GUILLAIN BARRE SYNDROME; HUMAN; MALE; PARKINSON DISEASE; PLASMAPHERESIS; POLYNEUROPATHY; PRIORITY JOURNAL; VITAMIN BLOOD LEVEL; VITAMIN SUPPLEMENTATION;

AGED; AGED, 80 AND OVER; DUODENUM; FEMALE; HUMANS; INFUSIONS, PARENTERAL; LEVODOPA; MALE; MIDDLE AGED; PARKINSON DISEASE; POLYNEUROPATHIES; VITAMIN B 12 DEFICIENCY;

EID: 84865474146     PISSN: 03405354     EISSN: 14321459     Source Type: Journal    
DOI: 10.1007/s00415-011-6396-z     Document Type: Article

References (16)

1. Onofrj M, Bonanni L, Cossu G, Manca D, Stocchi F, Thomas A (2009) Emergencies in parkinsonism: akinetic crisis, life-threatening dyskinesias, and polyneuropathy during L-Dopa gel treatment. Parkinsonism Relat Disord 15(Suppl 3):S233-S236
2. Santos-García D, Macías M, Llaneza M, Grande M, de la Fuente-Fernández R (2011) Serum vitamin B (12) and folate levels in Parkinson's disease patients treated with duodenal levodopa infusion. Mov Disord 26:558-559
3. Vallderiola F, Cámara A (2010) Intraduodenal infusion of levodopa. Rev Neurol 51:41-48
4. Palasí A, Fábregues O, Hernández-Vara J, Seoane JL, Gámez J, Álvarez-Sabín J (2010) Small fiber peripheral neuropathy presentation after starting treatment with continuous intraduodenal levodopa infusion in one patient with Parkinson disease. Poster presentation in 7th international congress on mental disfunction and other non-motor features in Parkinson's disease, Barcelona 2010
5. Antonini A, Isaias IU, Canesi M et al (2007) Duodenal levodopa infusion for advanced Parkinson's disease: 12-month treatment outcome. Mov Disord 22:1145-1149
6. Manca D, Cossu G, Murgia D et al (2009) Reversible encephalopathy and axonal neuropathy in Parkinson's disease during duodopa therapy. Mov Disord 24:2293-2294
7. Urban PP, Wellach I, Faiss S et al (2010) Subacute axonal neuropathy in Parkinson's disease with cobalamin and vitamin B6 deficiency under duodopa therapy. Mov Disord 25:1748-1752
8. Meppelink AM, Nyman R, van Laar T, Drent M, Prins T, Leenders KL (2011) Transcutaneous port for continuous duodenal levodopa/carbidopa administration in Parkinson's disease. Mov Disord 26:231-234
9. Klostermann F, Jugel C, Müller T, Marzinzik F (2011) Malnutritional polyneuropathy under intestinal levodopa infusion. J Neural Transm (epub ahead of print)
10. Toth C, Brown MS, Furtado S, Suchowersky O, Zochodne D (2008) Neuropathy as a potential complication of levodopa use in Parkinson's disease. Mov Disord 23:1850-1859
11. Schneider JS, Diamond SG, Markham CH (1987) Parkinson's disease: sensory and motor problems in arms and hands. Neurology 37:951-956
12. Westin J, Nyholm D, Pålhagen S et al (2011) A pharmacokineticpharmacodynamic model for duodenal levodopa infusion. Clin Neuropharmacol 34:61-65
13. Antonini A, Bondiolotti G, Natuzzi F, Bareggi SR (2010) Levodopa and 3-OMD levels in Parkinson patients treated with duodopa. Eur Neuropsychoparmacol 20:683-687
14. Savage DG, Lindenbaum J, Stabler SP, Allen RH (1994) Sensitivity of serum methylmalonic acid and total homocysteine determinations for diagnosing cobalamin and folate deficiencies. A J Med 96:239-246
15. Green R, Kinsella LJ (1995) Current concepts in the diagnosis of cobalamin deficiency. Neurology 45:1435-1440
16. Carrillo F (2010) This case was presented by Fátima Carrillo as brief talk in the "LVII Reunión Anual de la Sociedad Española de Neurología", Barcelona (Unpublished)