Serial correlation in optimal design for nonlinear mixed effects models

Journal of Pharmacokinetics and Pharmacodynamics

Volumn 39, Issue 3, 2012, Pages 239-249

  Nyberg, Joakim ^a   Höglund, Richard ^a,b   Bergstrand, Martin ^a   Karlsson, Mats O ^a   Hooker, Andrew C ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Autocorrelation; ED optimal designs; Population optimal design; Robust designs; Serial correlation

Indexed keywords

ANALYTICAL ERROR; ARTICLE; COMPUTER PROGRAM; CORRELATION ANALYSIS; EXPERIMENTAL DESIGN; MATHEMATICAL ANALYSIS; NONLINEAR MIXED EFFECTS MODEL; OPTIMAL EXPERIMENTAL DESIGN; POPULATION MODEL; PRIORITY JOURNAL; SAMPLING; SERIAL CORRELATION; SIGNAL NOISE RATIO; SIMULATION; STATISTICS; THEORY;

MODELS, BIOLOGICAL; NONLINEAR DYNAMICS;

EID: 84865453742     PISSN: 1567567X     EISSN: 15738744     Source Type: Journal    
DOI: 10.1007/s10928-012-9245-5     Document Type: Article

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