A genome-wide analysis of lentivector integration sites using targeted sequence capture and next generation sequencing technology

Infection, Genetics and Evolution

Volumn 12, Issue 7, 2012, Pages 1349-1354

  Ustek, Duran ^a   Sirma, Sema ^a   Gumus, Ergun ^a   Arikan, Muzaffer ^a   Cakiris, Aris ^a   Abaci, Neslihan ^a   Mathew, Jaicy ^a   Emrence, Zeliha ^a   Azakli, Hulya ^a   Cosan, Fulya ^a   Cakar, Atilla ^a   Parlak, Mahmut ^a   Kursun, Olcay ^a  

^a ISTANBUL UNIVERSITY   (Turkey)

Author keywords

Lentivector integration; Next generation sequencing; Targeted DNA capture; Virus

Indexed keywords

DNA FRAGMENT; LENTIVIRUS VECTOR; VIRUS RNA;

ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; CPG ISLAND; DNA DETERMINATION; DNA FLANKING REGION; DNA PROBE; DNA SEQUENCE; GENE TECHNOLOGY; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; INTRON; LENTIVIRINAE; LENTIVIRUS INFECTION; LONG TERMINAL REPEAT; NEXT GENERATION SEQUENCING TECHNOLOGY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; TARGETED DNA SEQUENCE CAPTURE TECHNOLOGY;

CELL SEPARATION; CHROMOSOMES, HUMAN; FLOW CYTOMETRY; GENES, NEOPLASM; GENOME, HUMAN; HEK293 CELLS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; LENTIVIRUS; MUTAGENESIS, INSERTIONAL; SEQUENCE ANALYSIS, DNA; TRANSFECTION; VIRUS INTEGRATION;

EID: 84865376801     PISSN: 15671348     EISSN: 15677257     Source Type: Journal    
DOI: 10.1016/j.meegid.2012.05.001     Document Type: Article

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