Impaired phagocytic capacity driven by downregulation of major phagocytosis-related cell surface molecules elicits an overall modulatory cytokine profile in neutrophils and monocytes from the indeterminate clinical form of Chagas disease

Immunobiology

Volumn 217, Issue 10, 2012, Pages 1005-1016

  Gomes, J A S ^a,b   Campi Azevedo, A C ^b   Teixeira Carvalho, A ^b   Silveira Lemos, D ^b,c   Vitelli Avelar, D ^b   Sathler Avelar, R ^b   Peruhype Magalhaes V ^b   Silvestre, K F ^a,b   Batista, M A ^b   Schachnik, N C C ^b   Correa Oliveira, R ^b,d   Eloi Santos, S ^b   Martins Filho, O A ^b  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

^c FEDERAL UNIVERSITY OF OURO PRETO   (Brazil)

^d Institute of Science and Technology of Tropical Diseases   (Brazil)

Author keywords

Cell surface molecules; Chagas disease; Cytokines; Monocytes; Neutrophils; Nitric oxide; Phagocytic capacity

Indexed keywords

BIOLOGICAL MARKER; CD86 ANTIGEN; COMPLEMENT COMPONENT C3B RECEPTOR; FC RECEPTOR; IMMUNOGLOBULIN G; INTERLEUKIN 10; INTERLEUKIN 12; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MONOKINE; NITRIC OXIDE; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; CELL PHAGOCYTOSIS; CHAGAS DISEASE; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; FEMALE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOMODULATION; IN VITRO STUDY; MALE; MONOCYTE; NEUTROPHIL; NONHUMAN; PARASITE IDENTIFICATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRYPANOSOMA CRUZI;

ANTIBODIES, PROTOZOAN; ANTIGEN-PRESENTING CELLS; ANTIGENS, CD86; ANTIGENS, PROTOZOAN; CELLS, CULTURED; CHAGAS DISEASE; CYTOKINES; HUMANS; IMMUNOGLOBULIN G; IMMUNOMODULATION; MONOCYTES; NEUTROPHILS; NITRIC OXIDE; PHAGOCYTOSIS; RECEPTORS, COMPLEMENT 3B; RECEPTORS, IGG; T-LYMPHOCYTES; TOLL-LIKE RECEPTORS; TRYPANOSOMA CRUZI;

EID: 84865369414     PISSN: 01712985     EISSN: 18783279     Source Type: Journal    
DOI: 10.1016/j.imbio.2012.01.014     Document Type: Article

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