Protective effect of NecroX, a novel necroptosis inhibitor, on gentamicin-induced ototoxicity

International Journal of Pediatric Otorhinolaryngology

Volumn 76, Issue 9, 2012, Pages 1265-1269

  Park, Moo Kyun ^a   Lee, Byung Don ^a   Chae, Sung Won ^b   Chi, Junhyuk ^c   Kwon, Seong Keun ^c   Song, Jae Jun ^c  

^a Soonchunhyang University   (South Korea)

^b Korea University College of Medicine   (South Korea)

^c Dongguk University Ilsan Hospital   (South Korea)

Author keywords

Gentamicin; Hair cells NecroX; Ototoxicity; Reactive oxygen species

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; ANTIOXIDANT; GENTAMICIN; NECROX; PROTECTIVE AGENT; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ANTIAPOPTOTIC ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL PROTECTION; COCHLEA; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG ACTIVITY; DRUG EFFECT; DRUG MECHANISM; HAIR CELL; HAIR CELL LOSS; IN VITRO STUDY; INNER EAR DISEASE; MOUSE; NEWBORN; NICK END LABELING; NONHUMAN; OTOTOXICITY; PRIORITY JOURNAL;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CELLS, CULTURED; COCHLEA; CYTOPROTECTION; GENTAMICINS; HAIR CELLS, AUDITORY; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; MICE; REACTIVE OXYGEN SPECIES; SULFONES;

EID: 84865361783     PISSN: 01655876     EISSN: 18728464     Source Type: Journal    
DOI: 10.1016/j.ijporl.2012.05.016     Document Type: Article

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