Prevalence of antibiotic-resistant bacteria in residents of nursing homes in a Swedish municipality: Healthcare staff knowledge of and adherence to principles of basic infection prevention

Scandinavian Journal of Infectious Diseases

Volumn 44, Issue 9, 2012, Pages 641-649

  Andersson, Helene ^a   Lindholm, Christina ^a   Iversen, Aina ^b   Giske, Christian G ^b   Örtqvist, Åke ^b,c   Kalin, Mats ^b   Fossum, Bjöörn ^a  

^a SOPHIAHEMMET UNIVERSITY COLLEGE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c Karolinska University Hospital ^*  (Sweden)

Author keywords

Antibiotic resistance; Infection prevention guidelines; Nursing homes; Resistant bacteria

Indexed keywords

ANTIBIOTIC AGENT;

ADULT; AGED; ANTIBIOTIC RESISTANCE; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL INFECTION; BACTERIAL TRANSMISSION; BACTERIUM ISOLATE; CONTROLLED STUDY; ESCHERICHIA COLI; EXTENDED SPECTRUM BETA LACTAMASE PRODUCING ENTEROBACTERIACEAE; FECES CULTURE; FEMALE; HUMAN; INFECTION CONTROL; INFECTION PREVENTION; MALE; MEDICAL STAFF; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; NURSING HOME; NURSING HOME PATIENT; PREVALENCE; PROFESSIONAL KNOWLEDGE; PUBLIC HOSPITAL; PULSED FIELD GEL ELECTROPHORESIS; RISK FACTOR; VANCOMYCIN RESISTANT ENTEROCOCCUS;

AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; BACTERIA; BACTERIAL INFECTIONS; CARRIER STATE; DRUG RESISTANCE, BACTERIAL; ELECTROPHORESIS, GEL, PULSED-FIELD; FECES; FEMALE; GUIDELINE ADHERENCE; HEALTH KNOWLEDGE, ATTITUDES, PRACTICE; HUMANS; INFECTION CONTROL; MALE; MIDDLE AGED; NURSING HOMES; NURSING STAFF; PREVALENCE; RISK FACTORS; SWEDEN;

EID: 84865346439     PISSN: 00365548     EISSN: 16511980     Source Type: Journal    
DOI: 10.3109/00365548.2012.671956     Document Type: Article

References (29)

1. Freire-Moran L, Aronsson B, Manz C, Gyssens IC, So AD, Monnet DL, et al. Critical shortage of new antibiotics in development against multidrug-resistant bacteria - time to react is now. Drug Resist Updat 2011;14:118-24.
2. Grundmann H, Livermore DM, Giske CG, Canton R, Rossolini GM, Campos J, et al. Carbapenem-non-susceptible Enterobacteriaceae in Europe: conclusions from a meeting of national experts. Euro Surveill 2010;15:46.
3. Schwaber MJ, Carmeli Y. Mortality and delay in effective therapy associated with extended-spectrum beta-lactamase production in Enterobacteriaceae bacteraemia: a systematic review and meta-analysis. J Antimicrob Chemother 2007; 60:913-20. (Pubitemid 47617735)
4. Swedres. A report on Swedish Antibiotic Utilization and Resistance in Human Medicine. http://www.strama.se/uploads/docs/Swedres%202010%20final.pdf (accessed 23 March 2012).
5. Paterson DL, Bonomo RA. Extended-spectrum betalactamases: a clinical update. Clin Microbiol Rev 2005;18: 657-86.
6. Mendelson G, Hait V, Ben-Israel J, Gronich D, Granot E, Raz R. Prevalence and risk factors of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae in an Israeli long-term care facility. Eur J Clin Microbiol Infect Dis 2005;24:17-22. (Pubitemid 40179127)
7. Rodriguez-Bano J, Navarro MD. Extended-spectrum betalactamases in ambulatory care: a clinical perspective. Clinical microbiology and infection: the officialpublication of the European Society of Clinical Microbiology and lnfectious Diseases 2008;14 Suppl 1:104-10. (Pubitemid 350284181)
8. Rooney PJ, O'Leary MC, Loughrey AC, McCalmont M, Smyth B, Donaghy P, et al. Nursing homes as a reservoir of extended-spectrum beta-lactamase (ESBL)-producing ciprofloxacin-resistant Escherichia coli. J Antimicrob Chemother 2009;64:635-41.
9. Safdar N, Maki DG. The commonality of risk factors for nosocomial colonization and infection with antimicrobialresistant Staphylococcus aureus, Enterococcus, Gramnegative bacilli, Clostridium difficile, and Candida. Ann Intern Med 2002;136:834-44. (Pubitemid 34568654)
10. Ben-Ami R, Rodriguez-Bano J, Arslan H, Pitout JD, Quentin C, Calbo ES, et al. A multinational survey of risk factors for infection with extended-spectrum beta-lactamase-producing Enterobacteriaceae in nonhospitalized patients. Clin Infect Dis 2009;49:682-90.
11. Pop-Vicas A, Mitchell SL, Kandel R, Schreiber R, D'Agata EM. Multidrug-resistant Gram-negative bacteria in a longterm care facility: prevalence and risk factors. J Am Geriatr Soc 2008;56:1276-80.
12. Pittet D, Allegranzi B, Sax H, Dharan S, Pessoa-Silva CL, Donaldson L, et al. Evidence-based model for hand transmission during patient care and the role of improved practices. Lancet Infect Dis 2006;6:641-52. (Pubitemid 44427733)
13. Pittet D, Allegranzi B, Boyce J; World Health Organization World Alliance for Patient Safety First Global Patient Safety Challenge Core Group of Experts. The World Health Organization Guidelines on Hand Hygiene in Health Care and their consensus recommendations. Infect Control Hosp Epidemiol 2009;30:611-22.
14. The National Board of Health and Welfare. The National Board of Health and Welfare ' s regulations on basic hygiene in the Swedish health service. Available at http://www.socialstyrelsen. se/Lists/Artikelkatalog/Attachments/ 8924/2007- 10-103.pdf (accessed 23 March 2012).
15. Ribot EM, Fair MA, Gautom R, Cameron DN, Hunter SB, Swaminathan B, et al. Standardization of pulsed-field gel electrophoresis protocols for the subtyping of Escherichia coli O157:H7, Salmonella, and Shigella for PulseNet. Foodborne Pathog Dis 2006;3:59-67.
16. Birkett CI, Ludlam HA, Woodford N, Brown DF, Brown NM, Roberts MT, et al. Real-time TaqMan PCR for rapid detection and typing of genes encoding CTX-M extended-spectrum beta-lactamases. J Med Microbiol 2007;56Pt1:52-5. (Pubitemid 46036275)
17. Cohen Stuart J, Dierikx C, Al Naiemi N, Karczmarek A, Van Hoek AH, Vos P, et al. Rapid detection of TEM, SHV and CTX-M extended-spectrum beta-lactamases in Enterobacteriaceae using ligation-mediated amplifi cation with microarray analysis. J Antimicrob Chemother 2010;65:1377-81.
18. Lindholm C, Westergren A, Holmström B, Axelsson C, Ulander K. Hygiene, wound management and wound microbiology - survey of fi ve hospitals, nine primary care clinics and homes for the elderly in six communities (in Swedish). Sweden: Kristianstad University, Sweden ISSN:1654-1421 (In Swedish). 2006.
19. Brolund A, Haeggman S, Edquist PJ, Gezelius L, Olsson-Liljequist B, Wisell KT, et al. The DiversiLab system versus pulsed-field gel electrophoresis: characterisation of extended spectrum beta-lactamase producing Escherichia coli and Klebsiella pneumoniae. Journal of microbiological methods 2010;83:224-30.
20. Titelman E, Iversen A, Kahlmeter G, Giske CG. Antimicrobial susceptibility to parenteral and oral agents in a largely polyclonal collection of CTX-M-14 and CTX-M-15- producing Escherichia coli and Klebsiella pneumoniae. APMIS: acta pathologica, microbiologica, et immunologica Scandinavica 2011;11:853-63.
21. Nilsson P, Alexandersson H, Ripa T. Use of broth enrichment and real-time PCR to exclude the presence of methicillinresistant Staphylococcus aureus in clinical samples: a sensitive screening approach. Clinical microbiology and infection: the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2005;11:1027-34. (Pubitemid 41748939)
22. Alsterlund R, Carlsson B, Gezelius L, Haeggman S, Olsson-Liljequist B. Multiresistant CTX-M-15 ESBL-producing Escherichia coli in southern Sweden: Description of an outbreak. Scand J Infect Dis 2009;41:410-5.
23. Alsterlund R, Axelsson C, Olsson-Liljequist B. Long-term carriage of extended-spectrum beta-lactamase-producing Escherichia coli. Scand J Infect Dis 2012;44:51-4.
24. van de Sande-Bruinsma N, Grundmann H, Verloo D, Tiemersma E, Monen J, Goossens H, et al. Antimicrobial drug use and resistance in Europe. Emerg Infect Dis 2008; 14:1722-30.
25. Stenhem M, Ortqvist A, Ringberg H, Larsson L, Olsson Liljequist B, Haeggman S, et al. Imported methicillinresistant Staphylococcus aureus, Sweden. Emerg Infect Dis 2010;16:189-96.
26. Albrich WC, Harbarth S. Health-care workers: source, vector, or victim of MRSA? Lancet Infect Dis 2008;8: 289-301. (Pubitemid 351615756)
27. Eveillard M, Pradelle MT, Lefrancq B, Guilloteau V, Rabjeau A, Kempf M, et al. Measurement of hand hygiene compliance and gloving practices in different settings for the elderly considering the location of hand hygiene opportunities during patient care. Am J Infect Control 2011;39:339-41.
28. Pan A, Domenighini F, Signorini L, Assini R, Catenazzi P, Lorenzotti S, et al. Adherence to hand hygiene in an Italian long-term care facility. Am J Infect Control 2008;36: 495-7.
29. Kampf G, Loffler H. Prevention of irritant contact dermatitis among health care workers by using evidence-based hand hygiene practices: a review. Ind Health 2007;45:645-52. (Pubitemid 350207334)