-
1
-
-
84863241921
-
Signaling network cross-talk in human pluripotent cells: A Smad2/3-regulated switch that controls the balance between self-renewal and differentiation
-
PMID:22385658
-
Singh AM, Reynolds D, Cliff T, Ohtsuka S, Mattheyses AL, Sun Y, et al. Signaling network cross-talk in human pluripotent cells: a Smad2/3-regulated switch that controls the balance between self-renewal and differentiation. Cell Stem Cell 2012; 10:312-26; PMID:22385658; http://dx.doi.org/10.1016/j.stem.2012. 01.014.
-
(2012)
Cell Stem Cell
, vol.10
, pp. 312-326
-
-
Singh, A.M.1
Reynolds, D.2
Cliff, T.3
Ohtsuka, S.4
Mattheyses, A.L.5
Sun, Y.6
-
2
-
-
33646549601
-
Activation of Akt signaling is sufficient to maintain pluripotency in mouse and primate embryonic stem cells
-
PMID:16407845
-
Watanabe S, Umehara H, Murayama K, Okabe M, Kimura T, Nakano T. Activation of Akt signaling is sufficient to maintain pluripotency in mouse and primate embryonic stem cells. Oncogene 2006; 25:2697-707; PMID:16407845; http://dx.doi.org/10.1038/sj.onc.1209307.
-
(2006)
Oncogene
, vol.25
, pp. 2697-2707
-
-
Watanabe, S.1
Umehara, H.2
Murayama, K.3
Okabe, M.4
Kimura, T.5
Nakano, T.6
-
3
-
-
0344845415
-
BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3
-
PMID:14636556
-
Ying QL, Nichols J, Chambers I, Smith A. BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. Cell 2003; 115:281-92; PMID:14636556; http://dx.doi.org/10.1016/S0092-8674(03)00847-X.
-
(2003)
Cell
, vol.115
, pp. 281-292
-
-
Ying, Q.L.1
Nichols, J.2
Chambers, I.3
Smith, A.4
-
4
-
-
44349170450
-
The ground state of embryonic stem cell self-renewal
-
PMID:18497825
-
Ying QL, Wray J, Nichols J, Batlle-Morera L, Doble B, Woodgett J, et al. The ground state of embryonic stem cell self-renewal. Nature 2008; 453:519-23; PMID:18497825; http://dx.doi.org/10.1038/nature06968.
-
(2008)
Nature
, vol.453
, pp. 519-523
-
-
Ying, Q.L.1
Wray, J.2
Nichols, J.3
Batlle-Morera, L.4
Doble, B.5
Woodgett, J.6
-
5
-
-
16844364151
-
LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism
-
PMID:15673569
-
Cartwright P, McLean C, Sheppard A, Rivett D, Jones K, Dalton S. LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism. Development 2005; 132:885-96; PMID:15673569; http://dx.doi.org/10. 1242/dev.01670.
-
(2005)
Development
, vol.132
, pp. 885-896
-
-
Cartwright, P.1
McLean, C.2
Sheppard, A.3
Rivett, D.4
Jones, K.5
Dalton, S.6
-
6
-
-
9144239955
-
Regulation of embryonic stem cell self-renewal by phosphoinositide 3-kinase-dependent signaling
-
PMID:15328362
-
Paling NR, Wheadon H, Bone HK, Welham MJ. Regulation of embryonic stem cell self-renewal by phosphoinositide 3-kinase-dependent signaling. J Biol Chem 2004; 279:48063-70; PMID:15328362; http://dx.doi.org/10.1074/jbc.M406467200.
-
(2004)
J Biol Chem
, vol.279
, pp. 48063-48070
-
-
Paling, N.R.1
Wheadon, H.2
Bone, H.K.3
Welham, M.J.4
-
7
-
-
34247154612
-
Regulation of Nanog expression by phosphoinositide 3-kinase-dependent signaling in murine embryonic stem cells
-
PMID:17204467
-
Storm MP, Bone HK, Beck CG, Bourillot PY, Schreiber V, Damiano T, et al. Regulation of Nanog expression by phosphoinositide 3-kinase-dependent signaling in murine embryonic stem cells. J Biol Chem 2007; 282:6265-73; PMID:17204467; http://dx.doi.org/10.1074/jbc.M610906200.
-
(2007)
J Biol Chem
, vol.282
, pp. 6265-6273
-
-
Storm, M.P.1
Bone, H.K.2
Beck, C.G.3
Bourillot, P.Y.4
Schreiber, V.5
Damiano, T.6
-
8
-
-
64649099533
-
Subcellular localization of glycogen synthase kinase 3beta controls embryonic stem cell self-renewal
-
PMID:19223464
-
Bechard M, Dalton S. Subcellular localization of glycogen synthase kinase 3beta controls embryonic stem cell self-renewal. Mol Cell Biol 2009; 29:2092-104; PMID:19223464; http://dx.doi.org/10.1128/MCB.01405-08.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 2092-2104
-
-
Bechard, M.1
Dalton, S.2
-
9
-
-
84863420854
-
Frat is a phosphatidylinositol 3-kinase/Akt-regulated determinant of glycogen synthase kinase 3β subcellular localization in pluripotent cells
-
PMID:22064483
-
Bechard M, Trost R, Singh AM, Dalton S. Frat is a phosphatidylinositol 3-kinase/Akt-regulated determinant of glycogen synthase kinase 3β subcellular localization in pluripotent cells. Mol Cell Biol 2012; 32:288-96; PMID:22064483; http://dx.doi.org/10.1128/MCB.05372-11.
-
(2012)
Mol Cell Biol
, vol.32
, pp. 288-296
-
-
Bechard, M.1
Trost, R.2
Singh, A.M.3
Dalton, S.4
-
10
-
-
33845996144
-
Activin a efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressed
-
PMID:17204604
-
McLean AB, D'Amour KA, Jones KL, Krishnamoorthy M, Kulik MJ, Reynolds DM, et al. Activin a efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressed. Stem Cells 2007; 25:29-38; PMID:17204604; http://dx.doi.org/10.1634/stemcells. 2006-0219.
-
(2007)
Stem Cells
, vol.25
, pp. 29-38
-
-
McLean, A.B.1
D'Amour, K.A.2
Jones, K.L.3
Krishnamoorthy, M.4
Kulik, M.J.5
Reynolds, D.M.6
-
11
-
-
1242267927
-
Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
-
PMID:14702635
-
Sato N, Meijer L, Skaltsounis L, Greengard P, Brivanlou AH. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nat Med 2004; 10:55-63; PMID:14702635; http://dx.doi.org/10.1038/nm979.
-
(2004)
Nat Med
, vol.10
, pp. 55-63
-
-
Sato, N.1
Meijer, L.2
Skaltsounis, L.3
Greengard, P.4
Brivanlou, A.H.5
-
12
-
-
80052475509
-
Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells
-
PMID:21841791
-
ten Berge D, Kurek D, Blauwkamp T, Koole W, Maas A, Eroglu E, et al. Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells. Nat Cell Biol 2011; 13:1070-5; PMID:21841791; http://dx.doi.org/10. 1038/ncb2314.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 1070-1075
-
-
Ten Berge, D.1
Kurek, D.2
Blauwkamp, T.3
Koole, W.4
Maas, A.5
Eroglu, E.6
-
13
-
-
67849092746
-
The cell cycle and Myc intersect with mechanisms that regulate pluripotency and reprogramming
-
PMID:19664987
-
Singh AM, Dalton S. The cell cycle and Myc intersect with mechanisms that regulate pluripotency and reprogramming. Cell Stem Cell 2009; 5:141-9; PMID:19664987; http://dx.doi.org/10.1016/j.stem.2009.07.003.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 141-149
-
-
Singh, A.M.1
Dalton, S.2
-
14
-
-
77956214711
-
Myc represses primitive endoderm differentiation in pluripotent stem cells
-
PMID:20804970
-
Smith KN, Singh AM, Dalton S. Myc represses primitive endoderm differentiation in pluripotent stem cells. Cell Stem Cell 2010; 7:343-54; PMID:20804970; http://dx.doi.org/10.1016/j.stem.2010.06.023.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 343-354
-
-
Smith, K.N.1
Singh, A.M.2
Dalton, S.3
-
15
-
-
79960030545
-
Indefinite self-renewal of ESCs through Myc/Max transcriptional complex-independent mechanisms
-
PMID:21726832
-
Hishida T, Nozaki Y, Nakachi Y, Mizuno Y, Okazaki Y, Ema M, et al. Indefinite self-renewal of ESCs through Myc/Max transcriptional complex-independent mechanisms. Cell Stem Cell 2011; 9:37-49; PMID:21726832; http://dx.doi.org/10.1016/j.stem.2011.04.020.
-
(2011)
Cell Stem Cell
, vol.9
, pp. 37-49
-
-
Hishida, T.1
Nozaki, Y.2
Nakachi, Y.3
Mizuno, Y.4
Okazaki, Y.5
Ema, M.6
-
16
-
-
77951920690
-
C-Myc regulates transcriptional pause release
-
PMID:20434984
-
Rahl PB, Lin CY, Seila AC, Flynn RA, McCuine S, Burge CB, et al. c-Myc regulates transcriptional pause release. Cell 2010; 141:432-45; PMID:20434984; http://dx.doi.org/10.1016/j.cell.2010.03.030.
-
(2010)
Cell
, vol.141
, pp. 432-445
-
-
Rahl, P.B.1
Lin, C.Y.2
Seila, A.C.3
Flynn, R.A.4
McCuine, S.5
Burge, C.B.6
-
17
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
PMID:16904174
-
Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006; 126:663-76; PMID:16904174; http://dx.doi.org/10.1016/j.cell.2006.07.024.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
18
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
PMID:18035408
-
Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007; 131:861-72; PMID:18035408; http://dx.doi.org/10.1016/j.cell. 2007.11.019.
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
Narita, M.4
Ichisaka, T.5
Tomoda, K.6
-
19
-
-
28644448149
-
Efficient differentiation of human embryonic stem cells to definitive endoderm
-
PMID:16258519
-
D'Amour KA, Agulnick AD, Eliazer S, Kelly OG, Kroon E, Baetge EE. Efficient differentiation of human embryonic stem cells to definitive endoderm. Nat Biotechnol 2005; 23:1534-41; PMID:16258519; http://dx.doi.org/10.1038/ nbt1163.
-
(2005)
Nat Biotechnol
, vol.23
, pp. 1534-1541
-
-
D'Amour, K.A.1
Agulnick, A.D.2
Eliazer, S.3
Kelly, O.G.4
Kroon, E.5
Baetge, E.E.6
-
20
-
-
34447528757
-
New cell lines from mouse epiblast share defining features with human embryonic stem cells
-
PMID:17597760
-
Tesar PJ, Chenoweth JG, Brook FA, Davies TJ, Evans EP, Mack DL, et al. New cell lines from mouse epiblast share defining features with human embryonic stem cells. Nature 2007; 448:196-9; PMID:17597760; http://dx.doi.org/10.1038/ nature05972.
-
(2007)
Nature
, vol.448
, pp. 196-199
-
-
Tesar, P.J.1
Chenoweth, J.G.2
Brook, F.A.3
Davies, T.J.4
Evans, E.P.5
Mack, D.L.6
-
21
-
-
34447527158
-
Derivation of pluripotent epiblast stem cells from mammalian embryos
-
PMID:17597762
-
Brons IG, Smithers LE, Trotter MW, Rugg-Gunn P, Sun B, Chuva de Sousa Lopes SM, et al. Derivation of pluripotent epiblast stem cells from mammalian embryos. Nature 2007; 448:191-5; PMID:17597762; http://dx.doi.org/10.1038/ nature05950.
-
(2007)
Nature
, vol.448
, pp. 191-195
-
-
Brons, I.G.1
Smithers, L.E.2
Trotter, M.W.3
Rugg-Gunn, P.4
Sun, B.5
Chuva De Sousa Lopes, S.M.6
-
22
-
-
33845351956
-
Beta-catenin destruction complex: Insights and questions from a structural perspective
-
PMID:17143292
-
Kimelman D, Xu W. beta-catenin destruction complex: insights and questions from a structural perspective. Oncogene 2006; 25:7482-91; PMID:17143292; http://dx.doi.org/10.1038/sj.onc.1210055.
-
(2006)
Oncogene
, vol.25
, pp. 7482-7491
-
-
Kimelman, D.1
Xu, W.2
-
23
-
-
79959999016
-
Differential requirement for the dual functions of β-catenin in embryonic stem cell self-renewal and germ layer formation
-
PMID:21685890
-
Lyashenko N, Winter M, Migliorini D, Biechele T, Moon RT, Hartmann C. Differential requirement for the dual functions of β-catenin in embryonic stem cell self-renewal and germ layer formation. Nat Cell Biol 2011; 13:753-61; PMID:21685890; http://dx.doi.org/10.1038/ncb2260.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 753-761
-
-
Lyashenko, N.1
Winter, M.2
Migliorini, D.3
Biechele, T.4
Moon, R.T.5
Hartmann, C.6
-
24
-
-
79959950773
-
Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation
-
PMID:21685889
-
Wray J, Kalkan T, Gomez-Lopez S, Eckardt D, Cook A, Kemler R, et al. Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation. Nat Cell Biol 2011; 13:838-45; PMID:21685889; http://dx.doi.org/10.1038/ncb2267.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 838-845
-
-
Wray, J.1
Kalkan, T.2
Gomez-Lopez, S.3
Eckardt, D.4
Cook, A.5
Kemler, R.6
-
25
-
-
79959963618
-
Opposing effects of Tcf3 and Tcf1 control Wnt stimulation of embryonic stem cell self-renewal
-
PMID:21685894
-
Yi F, Pereira L, Hoffman JA, Shy BR, Yuen CM, Liu DR, et al. Opposing effects of Tcf3 and Tcf1 control Wnt stimulation of embryonic stem cell self-renewal. Nat Cell Biol 2011; 13:762-70; PMID:21685894; http://dx.doi.org/ 10.1038/ncb2283.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 762-770
-
-
Yi, F.1
Pereira, L.2
Hoffman, J.A.3
Shy, B.R.4
Yuen, C.M.5
Liu, D.R.6
-
26
-
-
37049008721
-
Self-renewal of human embryonic stem cells requires insulin-like growth factor-1 receptor and ERBB2 receptor signaling
-
PMID:17761519
-
Wang L, Schulz TC, Sherrer ES, Dauphin DS, Shin S, Nelson AM, et al. Self-renewal of human embryonic stem cells requires insulin-like growth factor-1 receptor and ERBB2 receptor signaling. Blood 2007; 110:4111-9; PMID:17761519; http://dx.doi.org/10.1182/blood-2007-03-082586.
-
(2007)
Blood
, vol.110
, pp. 4111-4119
-
-
Wang, L.1
Schulz, T.C.2
Sherrer, E.S.3
Dauphin, D.S.4
Shin, S.5
Nelson, A.M.6
|