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Volumn 5, Issue , 2012, Pages

Structural, functional and molecular analysis of the effects of aging in the small intestine and colon of C57BL/6J mice

Author keywords

Aging; C57BL 6J mice; Colon; Diet; DNA methylation; Fat; Microbiota; Morphology; Small intestine; Transcriptomics

Indexed keywords

CUBILIN; DNA; RNA 16S;

EID: 84865328689     PISSN: None     EISSN: 17558794     Source Type: Journal    
DOI: 10.1186/1755-8794-5-38     Document Type: Article
Times cited : (48)

References (60)
  • 1
    • 77950353786 scopus 로고    scopus 로고
    • Homeostasis and inflammation in the intestine
    • 10.1016/j.cell.2010.01.023 20303876
    • Homeostasis and inflammation in the intestine. Garrett WS, Gordon JI, Glimcher LH, Cell 2010 140 6 859 870 10.1016/j.cell.2010.01.023 20303876
    • (2010) Cell , vol.140 , Issue.6 , pp. 859-870
    • Garrett, W.S.1    Gordon, J.I.2    Glimcher, L.H.3
  • 2
    • 79951675379 scopus 로고    scopus 로고
    • Innate immunity in the small intestine
    • 10.1097/MOG.0b013e3283438dea 21248635
    • Innate immunity in the small intestine. Santaolalla R, Fukata M, Abreu MT, Curr Opin Gastroenterol 2011 27 2 125 131 10.1097/MOG.0b013e3283438dea 21248635
    • (2011) Curr Opin Gastroenterol , vol.27 , Issue.2 , pp. 125-131
    • Santaolalla, R.1    Fukata, M.2    Abreu, M.T.3
  • 4
    • 70349899283 scopus 로고    scopus 로고
    • The intestinal epithelial barrier: Does it become impaired with age?
    • 10.1159/000228556 19786747
    • The intestinal epithelial barrier: does it become impaired with age? Meier J, Sturm A, Dig Dis 2009 27 3 240 245 10.1159/000228556 19786747
    • (2009) Dig Dis , vol.27 , Issue.3 , pp. 240-245
    • Meier, J.1    Sturm, A.2
  • 5
    • 79952117762 scopus 로고    scopus 로고
    • Host-bacteria interactions in the intestine: Homeostasis to chronic inflammation
    • 10.1002/wsbm.48 20836012
    • Host-bacteria interactions in the intestine: homeostasis to chronic inflammation. Barbosa T, Rescigno M, Wiley Interdiscip Rev Syst Biol Med 2010 2 1 80 97 10.1002/wsbm.48 20836012
    • (2010) Wiley Interdiscip Rev Syst Biol Med , vol.2 , Issue.1 , pp. 80-97
    • Barbosa, T.1    Rescigno, M.2
  • 6
    • 70349757681 scopus 로고    scopus 로고
    • Satiety and the anorexia of ageing
    • 19684553
    • Satiety and the anorexia of ageing. Benelam B, Br J Community Nurs 2009 14 8 332 335 19684553
    • (2009) Br J Community Nurs , vol.14 , Issue.8 , pp. 332-335
    • Benelam, B.1
  • 7
    • 55049123496 scopus 로고    scopus 로고
    • The clinical significance of gastrointestinal changes with aging
    • 10.1097/MCO.0b013e32830b5d37 18685464
    • The clinical significance of gastrointestinal changes with aging. Bhutto A, Morley JE, Curr Opin Clin Nutr Metab Care 2008 11 5 651 660 10.1097/MCO.0b013e32830b5d37 18685464
    • (2008) Curr Opin Clin Nutr Metab Care , vol.11 , Issue.5 , pp. 651-660
    • Bhutto, A.1    Morley, J.E.2
  • 9
    • 84925970592 scopus 로고    scopus 로고
    • Changes in food intake and its relationship to weight loss during advanced age
    • 20703055
    • Changes in food intake and its relationship to weight loss during advanced age. McDonald RB, Ruhe RC, Interdiscip Top Gerontol 2010 37 51 63 20703055
    • (2010) Interdiscip Top Gerontol , vol.37 , pp. 51-63
    • McDonald, R.B.1    Ruhe, R.C.2
  • 10
    • 34247534646 scopus 로고    scopus 로고
    • Basic mechanisms of the aging gastrointestinal tract
    • 10.1159/000099474 17468545
    • Basic mechanisms of the aging gastrointestinal tract. Salles N, Dig Dis 2007 25 2 112 117 10.1159/000099474 17468545
    • (2007) Dig Dis , vol.25 , Issue.2 , pp. 112-117
    • Salles, N.1
  • 11
    • 78449285662 scopus 로고    scopus 로고
    • Molecular basis for age-related changes in ileum: Involvement of Bax/caspase-dependent mitochondrial apoptotic signaling
    • 10.1016/j.exger.2010.08.019 20840861
    • Molecular basis for age-related changes in ileum: involvement of Bax/caspase-dependent mitochondrial apoptotic signaling. Lee EK, Jung KJ, Choi J, Kim HJ, Han YK, Jeong KS, Ji AR, Park JK, Yu BP, Chung HY, Exp Gerontol 2010 45 12 970 976 10.1016/j.exger.2010.08.019 20840861
    • (2010) Exp Gerontol , vol.45 , Issue.12 , pp. 970-976
    • Lee, E.K.1    Jung, K.J.2    Choi, J.3    Kim, H.J.4    Han, Y.K.5    Jeong, K.S.6    Ji, A.R.7    Park, J.K.8    Yu, B.P.9    Chung, H.Y.10
  • 12
    • 0032526476 scopus 로고    scopus 로고
    • Age changes in stem cells of murine small intestinal crypts
    • 10.1006/excr.1998.4001 9637773
    • Age changes in stem cells of murine small intestinal crypts. Martin K, Kirkwood TB, Potten CS, Exp Cell Res 1998 241 2 316 323 10.1006/excr.1998.4001 9637773
    • (1998) Exp Cell Res , vol.241 , Issue.2 , pp. 316-323
    • Martin, K.1    Kirkwood, T.B.2    Potten, C.S.3
  • 14
    • 0036481316 scopus 로고    scopus 로고
    • Nutrient absorption and intestinal adaptation with ageing
    • 10.1053/bega.2001.0262 11977925
    • Nutrient absorption and intestinal adaptation with ageing. Woudstra T, Thomson AB, Best Pract Res Clin Gastroenterol 2002 16 1 1 15 10.1053/bega.2001.0262 11977925
    • (2002) Best Pract Res Clin Gastroenterol , vol.16 , Issue.1 , pp. 1-15
    • Woudstra, T.1    Thomson, A.B.2
  • 15
    • 9644274090 scopus 로고    scopus 로고
    • Intrinsic ageing of gut epithelial stem cells
    • 10.1016/j.mad.2004.09.004 15563938
    • Intrinsic ageing of gut epithelial stem cells. Kirkwood TB, Mech Ageing Dev 2004 125 12 911 915 10.1016/j.mad.2004.09.004 15563938
    • (2004) Mech Ageing Dev , vol.125 , Issue.12 , pp. 911-915
    • Kirkwood, T.B.1
  • 16
    • 76449114803 scopus 로고    scopus 로고
    • Small intestinal bacterial overgrowth: Histopathologic features and clinical correlates in an underrecognized entity
    • 20121616
    • Small intestinal bacterial overgrowth: histopathologic features and clinical correlates in an underrecognized entity. Lappinga PJ, Abraham SC, Murray JA, Vetter EA, Patel R, Wu TT, Arch Pathol Lab Med 2010 134 2 264 270 20121616
    • (2010) Arch Pathol Lab Med , vol.134 , Issue.2 , pp. 264-270
    • Lappinga, P.J.1    Abraham, S.C.2    Murray, J.A.3    Vetter, E.A.4    Patel, R.5    Wu, T.T.6
  • 17
    • 49949104600 scopus 로고    scopus 로고
    • Small intestinal bacterial overgrowth
    • 10.1080/00365520801947074 18609165
    • Small intestinal bacterial overgrowth. Rana SV, Bhardwaj SB, Scand J Gastroenterol 2008 43 9 1030 1037 10.1080/00365520801947074 18609165
    • (2008) Scand J Gastroenterol , vol.43 , Issue.9 , pp. 1030-1037
    • Rana, S.V.1    Bhardwaj, S.B.2
  • 18
    • 77949285392 scopus 로고    scopus 로고
    • Human intestinal microbiota and healthy ageing
    • 10.1016/j.arr.2009.10.004 19874918
    • Human intestinal microbiota and healthy ageing. Tiihonen K, Ouwehand AC, Rautonen N, Ageing Res Rev 2010 9 2 107 116 10.1016/j.arr.2009.10.004 19874918
    • (2010) Ageing Res Rev , vol.9 , Issue.2 , pp. 107-116
    • Tiihonen, K.1    Ouwehand, A.C.2    Rautonen, N.3
  • 19
    • 77955602581 scopus 로고    scopus 로고
    • Through ageing, and beyond: Gut microbiota and inflammatory status in seniors and centenarians
    • 10.1371/journal.pone.0010667 20498852
    • Through ageing, and beyond: gut microbiota and inflammatory status in seniors and centenarians. Biagi E, Nylund L, Candela M, Ostan R, Bucci L, Pini E, Nikkila J, Monti D, Satokari R, Franceschi C, et al. PLoS One 2010 5 5 10667 10.1371/journal.pone.0010667 20498852
    • (2010) PLoS One , vol.5 , Issue.5 , pp. 510667
    • Biagi, E.1    Nylund, L.2    Candela, M.3    Ostan, R.4    Bucci, L.5    Pini, E.6    Nikkila, J.7    Monti, D.8    Satokari, R.9    Franceschi, C.10
  • 22
    • 33644554194 scopus 로고    scopus 로고
    • Gene expression changes reveal patterns of aging in the rat digestive tract
    • 10.1016/j.arr.2005.06.005 16260189
    • Gene expression changes reveal patterns of aging in the rat digestive tract. Englander EW, Ageing Res Rev 2005 4 4 564 578 10.1016/j.arr.2005.06.005 16260189
    • (2005) Ageing Res Rev , vol.4 , Issue.4 , pp. 564-578
    • Englander, E.W.1
  • 23
    • 0037316303 scopus 로고    scopus 로고
    • A comparison of normalization methods for high density oligonucleotide array data based on variance and bias
    • 10.1093/bioinformatics/19.2.185 12538238
    • A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bolstad BM, Irizarry RA, Astrand M, Speed TP, Bioinformatics 2003 19 2 185 193 10.1093/bioinformatics/19.2.185 12538238
    • (2003) Bioinformatics , vol.19 , Issue.2 , pp. 185-193
    • Bolstad, B.M.1    Irizarry, R.A.2    Astrand, M.3    Speed, T.P.4
  • 26
    • 85074914953 scopus 로고    scopus 로고
    • A PCR primer bank for quantitative gene expression analysis
    • 10.1093/nar/gng154 14654707
    • A PCR primer bank for quantitative gene expression analysis. Wang X, Seed B, Nucleic Acids Res 2003 31 24 154 10.1093/nar/gng154 14654707
    • (2003) Nucleic Acids Res , vol.31 , Issue.24 , pp. 5154
    • Wang, X.1    Seed, B.2
  • 27
    • 0033990048 scopus 로고    scopus 로고
    • Primer3 on the WWW for general users and for biologist programmers
    • 10547847
    • Primer3 on the WWW for general users and for biologist programmers. Rozen S, Skaletsky H, Methods Mol Biol 2000 132 365 386 10547847
    • (2000) Methods Mol Biol , vol.132 , pp. 365-386
    • Rozen, S.1    Skaletsky, H.2
  • 28
    • 77951977802 scopus 로고    scopus 로고
    • Comparative analysis of fecal DNA extraction methods with phylogenetic microarray: Effective recovery of bacterial and archaeal DNA using mechanical cell lysis
    • In Press, Corrected Proof
    • Comparative analysis of fecal DNA extraction methods with phylogenetic microarray: effective recovery of bacterial and archaeal DNA using mechanical cell lysis. Salonen A, Nikkilä J, Jalanka-Tuovinen J, Immonen O, Rajilic-Stojanovic M, Kekkonen RA, Palva A, de Vos WM, J Microbiol Methods 2010 In Press, Corrected Proof
    • (2010) J Microbiol Methods
    • Salonen, A.1    Nikkilä, J.2    Jalanka-Tuovinen, J.3    Immonen, O.4    Rajilic-Stojanovic, M.5    Kekkonen, R.A.6    Palva, A.7    De Vos, W.M.8
  • 29
    • 77950199929 scopus 로고    scopus 로고
    • Age-related inflammation: The contribution of different organs, tissues and systems. How to face it for therapeutic approaches
    • 10.2174/138161210790883840 20388071
    • Age-related inflammation: the contribution of different organs, tissues and systems. How to face it for therapeutic approaches. Cevenini E, Caruso C, Candore G, Capri M, Nuzzo D, Duro G, Rizzo C, Colonna-Romano G, Lio D, Di Carlo D, et al. Curr Pharm Des 2010 16 6 609 618 10.2174/138161210790883840 20388071
    • (2010) Curr Pharm des , vol.16 , Issue.6 , pp. 609-618
    • Cevenini, E.1    Caruso, C.2    Candore, G.3    Capri, M.4    Nuzzo, D.5    Duro, G.6    Rizzo, C.7    Colonna-Romano, G.8    Lio, D.9    Di Carlo, D.10
  • 30
    • 84884453781 scopus 로고    scopus 로고
    • The mouse in aging research
    • Elsevier Inc Fox JG, Davisson MT, Quimby FW, Barthold SW, Newcomer CE, Smith AL 2
    • The Mouse in Aging Research. Flurkey K, Currer JM, Harrison DE, The Mouse in Biomedical Research Elsevier Inc, Fox JG, Davisson MT, Quimby FW, Barthold SW, Newcomer CE, Smith AL, 2 2007 637 672
    • (2007) The Mouse in Biomedical Research , pp. 637-672
    • Flurkey, K.1    Currer, J.M.2    Harrison, D.E.3
  • 31
    • 84871739875 scopus 로고    scopus 로고
    • http://research.jax.org/faculty/harrison/ger1vLifespan1.html
  • 32
    • 0035872002 scopus 로고    scopus 로고
    • Age-associated changes in gene expression patterns in the duodenum and colon of rats
    • 10.1016/S0047-6374(00)00254-2 11240159
    • Age-associated changes in gene expression patterns in the duodenum and colon of rats. Lee HM, Greeley GH Jr, Englander EW, Mech Ageing Dev 2001 122 4 355 371 10.1016/S0047-6374(00)00254-2 11240159
    • (2001) Mech Ageing Dev , vol.122 , Issue.4 , pp. 355-371
    • Lee, H.M.1    Greeley Jr., G.H.2    Englander, E.W.3
  • 33
    • 0035031562 scopus 로고    scopus 로고
    • Cubilin, a multifunctional epithelial receptor: An overview
    • 10.1007/s001090100193 11409706
    • Cubilin, a multifunctional epithelial receptor: an overview. Kozyraki R, J Mol Med 2001 79 4 161 167 10.1007/s001090100193 11409706
    • (2001) J Mol Med , vol.79 , Issue.4 , pp. 161-167
    • Kozyraki, R.1
  • 34
    • 0032588494 scopus 로고    scopus 로고
    • Vitamin B12 deficiency in the elderly
    • 10.1146/annurev.nutr.19.1.357 10448529
    • Vitamin B12 deficiency in the elderly. Baik HW, Russell RM, Annu Rev Nutr 1999 19 357 377 10.1146/annurev.nutr.19.1.357 10448529
    • (1999) Annu Rev Nutr , vol.19 , pp. 357-377
    • Baik, H.W.1    Russell, R.M.2
  • 35
    • 8344223045 scopus 로고    scopus 로고
    • Cobalamin: A critical vitamin in the elderly
    • 10.1016/j.ypmed.2004.04.047 15539065
    • Cobalamin: a critical vitamin in the elderly. Wolters M, Strohle A, Hahn A, Prev Med 2004 39 6 1256 1266 10.1016/j.ypmed.2004.04.047 15539065
    • (2004) Prev Med , vol.39 , Issue.6 , pp. 1256-1266
    • Wolters, M.1    Strohle, A.2    Hahn, A.3
  • 36
    • 78649409678 scopus 로고    scopus 로고
    • B vitamins and the aging brain
    • 21091944
    • B vitamins and the aging brain. Selhub J, Troen A, Rosenberg IH, Nutr Rev 2010 68 Suppl 2 112 S118 21091944
    • (2010) Nutr Rev , vol.68 , Issue.SUPPL. 2
    • Selhub, J.1    Troen, A.2    Rosenberg, I.H.3
  • 37
    • 0037297716 scopus 로고    scopus 로고
    • The methionine-homocysteine cycle and its effects on cognitive diseases
    • 12611557
    • The methionine-homocysteine cycle and its effects on cognitive diseases. Miller AL, Altern Med Rev 2003 8 1 7 19 12611557
    • (2003) Altern Med Rev , vol.8 , Issue.1 , pp. 7-19
    • Miller, A.L.1
  • 38
    • 36248955119 scopus 로고    scopus 로고
    • Homocysteine, vitamins, and vascular disease prevention
    • 17991676
    • Homocysteine, vitamins, and vascular disease prevention. McCully KS, Am J Clin Nutr 2007 86 5 1563S 1568S 17991676
    • (2007) Am J Clin Nutr , vol.86 , Issue.5
    • McCully, K.S.1
  • 39
    • 14544303158 scopus 로고    scopus 로고
    • Low plasma vitamin B12 is associated with lower BMD: The Framingham Osteoporosis Study
    • 10.1359/jbmr.2005.20.1.152 15619681
    • Low plasma vitamin B12 is associated with lower BMD: the Framingham Osteoporosis Study. Tucker KL, Hannan MT, Qiao N, Jacques PF, Selhub J, Cupples LA, Kiel DP, J Bone Miner Res 2005 20 1 152 158 10.1359/jbmr.2005.20.1.152 15619681
    • (2005) J Bone Miner Res , vol.20 , Issue.1 , pp. 152-158
    • Tucker, K.L.1    Hannan, M.T.2    Qiao, N.3    Jacques, P.F.4    Selhub, J.5    Cupples, L.A.6    Kiel, D.P.7
  • 41
    • 0022559689 scopus 로고
    • Ageing and small-bowel mucosa: A morphometric study
    • 3732818
    • Ageing and small-bowel mucosa: a morphometric study. Corazza GR, Frazzoni M, Gatto MR, Gasbarrini G, Gerontology 1986 32 1 60 65 3732818
    • (1986) Gerontology , vol.32 , Issue.1 , pp. 60-65
    • Corazza, G.R.1    Frazzoni, M.2    Gatto, M.R.3    Gasbarrini, G.4
  • 42
    • 0021682710 scopus 로고
    • Effect of aging upon small intestinal structure in the Fischer rat
    • 10.1093/geronj/39.6.642 6491177
    • Effect of aging upon small intestinal structure in the Fischer rat. Holt PR, Pascal RR, Kotler DP, J Gerontol 1984 39 6 642 647 10.1093/geronj/39.6.642 6491177
    • (1984) J Gerontol , vol.39 , Issue.6 , pp. 642-647
    • Holt, P.R.1    Pascal, R.R.2    Kotler, D.P.3
  • 43
    • 0026606927 scopus 로고
    • Ageing and duodenal morphometry
    • 10.1136/jcp.45.5.450 1597527
    • Ageing and duodenal morphometry. Lipski PS, Bennett MK, Kelly PJ, James OF, J Clin Pathol 1992 45 5 450 452 10.1136/jcp.45.5.450 1597527
    • (1992) J Clin Pathol , vol.45 , Issue.5 , pp. 450-452
    • Lipski, P.S.1    Bennett, M.K.2    Kelly, P.J.3    James, O.F.4
  • 44
    • 0018076768 scopus 로고
    • Age changes in small-intestinal mucosa
    • 81408
    • Age changes in small-intestinal mucosa. Warren PM, Pepperman MA, Montgomery RD, Lancet 1978 2 8094 849 850 81408
    • (1978) Lancet , vol.2 , Issue.8094 , pp. 849-850
    • Warren, P.M.1    Pepperman, M.A.2    Montgomery, R.D.3
  • 45
    • 79953039730 scopus 로고    scopus 로고
    • Immunosenescence: Implications for vaccination programmes in adults
    • 10.1016/j.maturitas.2011.01.011 21316879
    • Immunosenescence: Implications for vaccination programmes in adults. Lang PO, Govind S, Michel JP, Aspinall R, Mitchell WA, Maturitas 2011 68 4 322 330 10.1016/j.maturitas.2011.01.011 21316879
    • (2011) Maturitas , vol.68 , Issue.4 , pp. 322-330
    • Lang, P.O.1    Govind, S.2    Michel, J.P.3    Aspinall, R.4    Mitchell, W.A.5
  • 48
    • 73749083928 scopus 로고    scopus 로고
    • Gene variants as determinants of longevity: Focus on the inflammatory factors
    • 10.1007/s00424-009-0726-3 19763607
    • Gene variants as determinants of longevity: focus on the inflammatory factors. Jylhava J, Hurme M, Pflugers Arch 2010 459 2 239 246 10.1007/s00424-009-0726-3 19763607
    • (2010) Pflugers Arch , vol.459 , Issue.2 , pp. 239-246
    • Jylhava, J.1    Hurme, M.2
  • 49
    • 80052594971 scopus 로고    scopus 로고
    • Inflammation and genetics: An insight in the centenarian model
    • 10.3378/027.083.0407 21846209
    • Inflammation and genetics: an insight in the centenarian model. Iannitti T, Palmieri B, Hum Biol 2011 83 4 531 559 10.3378/027.083.0407 21846209
    • (2011) Hum Biol , vol.83 , Issue.4 , pp. 531-559
    • Iannitti, T.1    Palmieri, B.2
  • 50
    • 77958462497 scopus 로고    scopus 로고
    • Innate and adaptive immune connections in inflammatory bowel diseases
    • 10.1097/MOG.0b013e32833f126d 20871398
    • Innate and adaptive immune connections in inflammatory bowel diseases. Rakoff-Nahoum S, Bousvaros A, Curr Opin Gastroenterol 2010 26 6 572 577 10.1097/MOG.0b013e32833f126d 20871398
    • (2010) Curr Opin Gastroenterol , vol.26 , Issue.6 , pp. 572-577
    • Rakoff-Nahoum, S.1    Bousvaros, A.2
  • 51
    • 34247384151 scopus 로고    scopus 로고
    • Intestinal bacteria and ageing
    • 10.1111/j.1365-2672.2007.03400.x 17448153
    • Intestinal bacteria and ageing. Woodmansey EJ, J Appl Microbiol 2007 102 5 1178 1186 10.1111/j.1365-2672.2007.03400.x 17448153
    • (2007) J Appl Microbiol , vol.102 , Issue.5 , pp. 1178-1186
    • Woodmansey, E.J.1
  • 52
    • 80052307460 scopus 로고    scopus 로고
    • The aging gut microbiota: New perspectives
    • 10.1016/j.arr.2011.03.004 21402177
    • The aging gut microbiota: new perspectives. Biagi E, Candela M, Franceschi C, Brigidi P, Ageing Res Rev 2011 10 4 428 429 10.1016/j.arr.2011.03. 004 21402177
    • (2011) Ageing Res Rev , vol.10 , Issue.4 , pp. 428-429
    • Biagi, E.1    Candela, M.2    Franceschi, C.3    Brigidi, P.4
  • 53
    • 67649479395 scopus 로고    scopus 로고
    • Protein expression analysis of inflammation-related colon carcinogenesis
    • 10.4103/1477-3163.51851 19491504
    • Protein expression analysis of inflammation-related colon carcinogenesis. Yasui Y, Tanaka T, J Carcinog 2009 8 10 10.4103/1477-3163.51851 19491504
    • (2009) J Carcinog , vol.8 , pp. 10
    • Yasui, Y.1    Tanaka, T.2
  • 54
    • 0038352053 scopus 로고    scopus 로고
    • Radical causes of cancer
    • 10.1038/nrc1046 12671666
    • Radical causes of cancer. Hussain SP, Hofseth LJ, Harris CC, Nat Rev Cancer 2003 3 4 276 285 10.1038/nrc1046 12671666
    • (2003) Nat Rev Cancer , vol.3 , Issue.4 , pp. 276-285
    • Hussain, S.P.1    Hofseth, L.J.2    Harris, C.C.3
  • 55
    • 0028925075 scopus 로고
    • Worsening risk for the development of dysplasia or cancer in patients with chronic ulcerative colitis
    • 7872273
    • Worsening risk for the development of dysplasia or cancer in patients with chronic ulcerative colitis. Lashner BA, Provencher KS, Bozdech JM, Brzezinski A, Am J Gastroenterol 1995 90 3 377 380 7872273
    • (1995) Am J Gastroenterol , vol.90 , Issue.3 , pp. 377-380
    • Lashner, B.A.1    Provencher, K.S.2    Bozdech, J.M.3    Brzezinski, A.4
  • 56
    • 79751489596 scopus 로고    scopus 로고
    • Molecular genetics of colorectal cancer
    • 10.1146/annurev-pathol-011110-130235 21090969
    • Molecular genetics of colorectal cancer. Fearon ER, Annu Rev Pathol 2011 6 479 507 10.1146/annurev-pathol-011110-130235 21090969
    • (2011) Annu Rev Pathol , vol.6 , pp. 479-507
    • Fearon, E.R.1
  • 57
    • 46749111024 scopus 로고    scopus 로고
    • Apc mice: Models, modifiers and mutants
    • 10.1016/j.prp.2008.03.004 18538487
    • Apc mice: models, modifiers and mutants. McCart AE, Vickaryous NK, Silver A, Pathol Res Pract 2008 204 7 479 490 10.1016/j.prp.2008.03.004 18538487
    • (2008) Pathol Res Pract , vol.204 , Issue.7 , pp. 479-490
    • McCart, A.E.1    Vickaryous, N.K.2    Silver, A.3
  • 58
    • 34548379030 scopus 로고    scopus 로고
    • Dextran sulfate sodium-induced colitis-associated neoplasia: A promising model for the development of chemopreventive interventions
    • 10.1111/j.1745-7254.2007.00695.x 17723178
    • Dextran sulfate sodium-induced colitis-associated neoplasia: a promising model for the development of chemopreventive interventions. Clapper ML, Cooper HS, Chang WC, Acta Pharmacol Sin 2007 28 9 1450 1459 10.1111/j.1745-7254.2007. 00695.x 17723178
    • (2007) Acta Pharmacol Sin , vol.28 , Issue.9 , pp. 1450-1459
    • Clapper, M.L.1    Cooper, H.S.2    Chang, W.C.3
  • 60
    • 78049443505 scopus 로고    scopus 로고
    • Epigenomics of human colon cancer
    • 20691710
    • Epigenomics of human colon cancer. Carmona FJ, Esteller M, Mutat Res 2010 693 1-2 53 60 20691710
    • (2010) Mutat Res , vol.693 , Issue.1-2 , pp. 53-60
    • Carmona, F.J.1    Esteller, M.2


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