Neonatal benzodiazepines exposure during breastfeeding

Journal of Pediatrics

Volumn 161, Issue 3, 2012, Pages 448-451

  Kelly, Lauren E ^a,b,c   Poon, Shirley ^a   Madadi, Parvaz ^d,e   Koren, Gideon ^b,d,e  

^a WESTERN UNIVERSITY   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

^c LONDON HEALTH SCIENCES CENTRE   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

^e HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALPRAZOLAM; AMFEBUTAMONE; BENZODIAZEPINE DERIVATIVE; CITALOPRAM; CLOBAZAM; CLONAZEPAM; CODEINE; DESVENLAFAXINE; DOMPERIDONE; FENTANYL; FLURAZEPAM; FLUVOXAMINE; LORAZEPAM; MIDAZOLAM; MORPHINE; OXYCODONE; PAROXETINE; PHENYTOIN; QUETIAPINE; RISPERIDONE; SERTRALINE; TRAZODONE; VENLAFAXINE; ZOPICLONE;

ARTICLE; BREAST FEEDING; BREAST MILK; CENTRAL NERVOUS SYSTEM DEPRESSION; COHORT ANALYSIS; CONFUSION; DEMOGRAPHY; DRUG SAFETY; FEMALE; FOLLOW UP; HEADACHE; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROSPECTIVE STUDY; SEDATION; SIDE EFFECT;

ADULT; ANXIETY; BENZODIAZEPINES; BREAST FEEDING; CONSCIOUSNESS DISORDERS; FEMALE; HUMANS; INFANT, NEWBORN; MILK, HUMAN; PUERPERAL DISORDERS; TRANQUILIZING AGENTS;

EID: 84865323996     PISSN: 00223476     EISSN: 10976833     Source Type: Journal    
DOI: 10.1016/j.jpeds.2012.03.003     Document Type: Article

References (21)

1. V.K. Burt, R. Suri, L. Altshuler, Z. Stowe, V.C. Hendrick, and E. Muntean The use of psychotropic medication during breast-feeding Am J Psychiatry 158 2001 1001 1009
2. American Academy of Pediatrics (AAP) Breastfeeding and the use of human milk Pediatrics 115 2005 496 506
3. M. Boland Exclusive breastfeeding should continue to six months Paediatr Child Health 10 2005 148 (Pubitemid 40559131)
4. A. Buist, T.R. Norman, and L. Dennerstein Breastfeeding and the use of psychotropic medication: a review J Affect Disord 19 1990 197 206 (Pubitemid 20209136)
5. A. Einarson, P. Selby, and G. Koren Abrupt discontinuation of psychotropic drugs during pregnancy: fear of teratogenic risk and impact of counselling J Psychiatry Neurosci 26 2001 44 48 (Pubitemid 32185179)
6. M.M. Iqbal, T. Sobhan, and T. Ryals Effects of commonly used benzodiazepines on the fetus, the neonate, and the nursing infant Psychiatric Serv 53 2002 39 49 (Pubitemid 34038614)
7. C.S. Birnbaum, L.S. Cohen, J.W. Bailey, L.R. Grush, L.M. Robertson, and Z.N. Stowe Serum concentrations of antidepressants and benzodiazepines in nursing infants: a case series Am Acad Pediatr 104 1999 1 6
8. T.W. Hale Medications and mothers' milk 2004 Pharasoft Publishing Amarillo (TX)
9. K. Ito, Y. Yamada, K. Nakamura, Y. Sawada, and T. Iga Classification of benzodiazepine hypnotics in humans based on receptor occupancy theory J Pharmacokinet Biopharm 21 1993 31 41 (Pubitemid 23261729)
10. G. Ciarimboli Role of organic cation transporters in drug-induced toxicity Expert Opin Drug Metab Toxicol 7 2011 159 174
11. J.W. Jonker, G. Merino, S. Musters, A.E. van Herwaarden, E. Bolscher, and E. Wagenaar Psychotropic medication and breast-feeding Adv Psychiatric Treat 11 2005 376
12. E.T. Rubin, A. Lee, and S. Ito When breastfeeding mothers need CNS-acting drugs Can J Clin Pharmacol 11 2004 257 266
13. G. Koren Maternal-fetal toxicology, a clinician's guide 3rd ed. 2001 Marcel Dekker New York
14. American College of Obstetricians and Gynecologists (ACOG) Practice bulletin No. 92: Clinical management guidelines for obstetrician-gynecologists: use of psychiatric medications during pregnancy and lactation Obstet Gynecol 111 2008 1001 1020
15. M.J. Gardner, B.A. Baris, K.D. Wilner, and S.H. Preskorn Effect of sertraline on the pharmacokinestics and protein binding of diazepam and protein binding of diazepam in healthy volunteers Clin Pharmacokinet 32 1997 43 49 (Pubitemid 27107719)
16. P.C. Hassan, B.A. Sproule, C.A. Naranjo, and N. Herrmann Dose-response evaluation of the interaction between sertraline and alprazolam in vivo J Clin Psychopharmacol 20 2000 150 158 (Pubitemid 30202356)
17. R.J. Summerfield, and M.S. Nielsen Excretion of lorazepam into breast milk Br J Anaesth 57 1985 1042 1043 (Pubitemid 16236255)
18. M. Wretlind Excretion of oxazepam in breast milk Eur J Clin Pharmacol 33 1987 209 210 (Pubitemid 17149238)
19. J. Lam, L. Kelly, C. Ciszkowski, B. Carleton, M. Hayden, and P. Madadi The incidence of central nervous system depression of neonates breastfed by mothers receiving oxycodone for postpartum analgesia J Pediatr 160 2012 33 37
20. E. Spina, V. Santoro, and C. D'Arrigo Clinically relevant pharmacokinetic drug interactions with second-generation antidepressants: an update Clin Therap 30 2008 1206 1227
21. T. Fukasawa, A. Suzuki, and K. Otani Effects of genetic polymorphism of cytochrome P450 enzymes on the pharmacokinetics of benzodiazepines J Clin Pharmacol Ther 32 2007 333 341 (Pubitemid 47063159)